Patterns of molecular evolution in pathogenesis-related proteins

Detalhes bibliográficos
Autor(a) principal: Scherer, Nicole de Miranda
Data de Publicação: 2005
Outros Autores: Thompson, Claudia Elizabeth, Freitas, Loreta Brandão de, Bonatto, Sandro Luis
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/23385
Resumo: The genes encoding 13 classes of pathogenesis-related (PR) proteins were examined for positive selection using maximum-likelihood (ML) models of codon substitution. The study involved 194 sequences from 54 species belonging to 37 genera. Although the sizes of the sequences examined varied from 237 bp for PR12 to 1,110 bp for PR7, most classes (9 out of 13) contained sequences made up of more than 400 nucleotides. Signs of positive selection were obtained for sites in PR proteins 4, 6, 8, 9 and 15 using an ML-based Bayesian method and likelihood ratio tests. These results confirm the importance of positive selection in proteins related to defense mechanisms already observed in a wide array of organisms.
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spelling Scherer, Nicole de MirandaThompson, Claudia ElizabethFreitas, Loreta Brandão deBonatto, Sandro Luis2010-06-05T04:17:24Z20051415-4757http://hdl.handle.net/10183/23385000527148The genes encoding 13 classes of pathogenesis-related (PR) proteins were examined for positive selection using maximum-likelihood (ML) models of codon substitution. The study involved 194 sequences from 54 species belonging to 37 genera. Although the sizes of the sequences examined varied from 237 bp for PR12 to 1,110 bp for PR7, most classes (9 out of 13) contained sequences made up of more than 400 nucleotides. Signs of positive selection were obtained for sites in PR proteins 4, 6, 8, 9 and 15 using an ML-based Bayesian method and likelihood ratio tests. These results confirm the importance of positive selection in proteins related to defense mechanisms already observed in a wide array of organisms.application/pdfengGenetics and molecular biology. Ribeirão Preto. Vol. 28, no. 4 (Dec. 2005), p. 645-653Evolução molecularPatogenicidadePathogenesis-related proteinsPRsMolecular variabilityPositive selectionMaximum-likelihood methodsPatterns of molecular evolution in pathogenesis-related proteinsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000527148.pdf000527148.pdfTexto completo (inglês)application/pdf257459http://www.lume.ufrgs.br/bitstream/10183/23385/1/000527148.pdfe386dbfdd398e1b5418aac793f9511e2MD51TEXT000527148.pdf.txt000527148.pdf.txtExtracted Texttext/plain33994http://www.lume.ufrgs.br/bitstream/10183/23385/2/000527148.pdf.txt3097c2a0af51fb542276b865d11b0471MD52THUMBNAIL000527148.pdf.jpg000527148.pdf.jpgGenerated Thumbnailimage/jpeg1663http://www.lume.ufrgs.br/bitstream/10183/23385/3/000527148.pdf.jpg310280928e82ad6a7c1aed419b07c17cMD5310183/233852019-06-20 02:35:41.710015oai:www.lume.ufrgs.br:10183/23385Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-06-20T05:35:41Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Patterns of molecular evolution in pathogenesis-related proteins
title Patterns of molecular evolution in pathogenesis-related proteins
spellingShingle Patterns of molecular evolution in pathogenesis-related proteins
Scherer, Nicole de Miranda
Evolução molecular
Patogenicidade
Pathogenesis-related proteins
PRs
Molecular variability
Positive selection
Maximum-likelihood methods
title_short Patterns of molecular evolution in pathogenesis-related proteins
title_full Patterns of molecular evolution in pathogenesis-related proteins
title_fullStr Patterns of molecular evolution in pathogenesis-related proteins
title_full_unstemmed Patterns of molecular evolution in pathogenesis-related proteins
title_sort Patterns of molecular evolution in pathogenesis-related proteins
author Scherer, Nicole de Miranda
author_facet Scherer, Nicole de Miranda
Thompson, Claudia Elizabeth
Freitas, Loreta Brandão de
Bonatto, Sandro Luis
author_role author
author2 Thompson, Claudia Elizabeth
Freitas, Loreta Brandão de
Bonatto, Sandro Luis
author2_role author
author
author
dc.contributor.author.fl_str_mv Scherer, Nicole de Miranda
Thompson, Claudia Elizabeth
Freitas, Loreta Brandão de
Bonatto, Sandro Luis
dc.subject.por.fl_str_mv Evolução molecular
Patogenicidade
topic Evolução molecular
Patogenicidade
Pathogenesis-related proteins
PRs
Molecular variability
Positive selection
Maximum-likelihood methods
dc.subject.eng.fl_str_mv Pathogenesis-related proteins
PRs
Molecular variability
Positive selection
Maximum-likelihood methods
description The genes encoding 13 classes of pathogenesis-related (PR) proteins were examined for positive selection using maximum-likelihood (ML) models of codon substitution. The study involved 194 sequences from 54 species belonging to 37 genera. Although the sizes of the sequences examined varied from 237 bp for PR12 to 1,110 bp for PR7, most classes (9 out of 13) contained sequences made up of more than 400 nucleotides. Signs of positive selection were obtained for sites in PR proteins 4, 6, 8, 9 and 15 using an ML-based Bayesian method and likelihood ratio tests. These results confirm the importance of positive selection in proteins related to defense mechanisms already observed in a wide array of organisms.
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2010-06-05T04:17:24Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/23385
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dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.pt_BR.fl_str_mv Genetics and molecular biology. Ribeirão Preto. Vol. 28, no. 4 (Dec. 2005), p. 645-653
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