Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista Brasileira de Geriatria e Gerontologia |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-98232015000200285 |
Resumo: | INTRODUCTION: Sarcopenia has been associated with increased morbidity and mortality in older people. However, there is still no consensus about the best diagnostic criteria for it. OBJECTIVE: This study aimed to evaluate different diagnostic criteria of sarcopenia and their relationship with muscle strength and functional capacity. METHODS: A cross-sectional study was carried out in Santa Maria-RS, Brazil. Body composition was measured by dual-energy X-ray absorptiometry (DXA). Physical performance was evaluated by the Timed-get-up-and-go test (TGUG). Muscle strength was measured with a handgrip dynamometer. The proposed criteria of sarcopenia were evaluated as follows: A) appendicular lean mass index (aLM/ht2), cutoffs 5.5 kg/m2, 2SD, 10th percentile, and 20th percentile of young reference; B) a linear regression model was used to adjust appendicular lean mass (aLM) for both height and fat mass, cutoff 20th percentile of elderly. RESULTS: In total, 104 women agreed to participate in the research, 39 young (20 to 40 years) and 65 elderly (over 60 years). The prevalence of sarcopenia varied from 0% to 17.2% according to the diagnostic criteria. Regarding muscle strength, the aLM/ht2 cutoff 10th percentile was the criterion with greater area under the ROC curve. However, there were no criteria with an area under the ROC curve greater than 0.5 when TGUG was the outcome. The reclassification showed that the criterion B reclassified 66.7% with normal grip strength as sarcopenic. CONCLUSION: Of these criteria, aLM/ht2 cutoff 10th percentile had stronger correlation with muscle strength. |
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Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacitySarcopeniaPostmenopauseMuscle StrengthCalibrationDiscrimination INTRODUCTION: Sarcopenia has been associated with increased morbidity and mortality in older people. However, there is still no consensus about the best diagnostic criteria for it. OBJECTIVE: This study aimed to evaluate different diagnostic criteria of sarcopenia and their relationship with muscle strength and functional capacity. METHODS: A cross-sectional study was carried out in Santa Maria-RS, Brazil. Body composition was measured by dual-energy X-ray absorptiometry (DXA). Physical performance was evaluated by the Timed-get-up-and-go test (TGUG). Muscle strength was measured with a handgrip dynamometer. The proposed criteria of sarcopenia were evaluated as follows: A) appendicular lean mass index (aLM/ht2), cutoffs 5.5 kg/m2, 2SD, 10th percentile, and 20th percentile of young reference; B) a linear regression model was used to adjust appendicular lean mass (aLM) for both height and fat mass, cutoff 20th percentile of elderly. RESULTS: In total, 104 women agreed to participate in the research, 39 young (20 to 40 years) and 65 elderly (over 60 years). The prevalence of sarcopenia varied from 0% to 17.2% according to the diagnostic criteria. Regarding muscle strength, the aLM/ht2 cutoff 10th percentile was the criterion with greater area under the ROC curve. However, there were no criteria with an area under the ROC curve greater than 0.5 when TGUG was the outcome. The reclassification showed that the criterion B reclassified 66.7% with normal grip strength as sarcopenic. CONCLUSION: Of these criteria, aLM/ht2 cutoff 10th percentile had stronger correlation with muscle strength. Universidade do Estado do Rio Janeiro2015-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-98232015000200285Revista Brasileira de Geriatria e Gerontologia v.18 n.2 2015reponame:Revista Brasileira de Geriatria e Gerontologiainstname:Universidade do Estado do Rio de Janeiro (UERJ)instacron:UFRJ10.1590/1809-9823.2015.14025info:eu-repo/semantics/openAccessSalame,MarceloCosta,Karen Koff daZottele,Lucas VenturiniMuradás,Raquel RodriguesTierno,Sibelle de AlmeidaSchettinger,Maria Rosa ChitolinaPremaor,MelissaBeck,Maristela de Oliveiraeng2015-07-28T00:00:00Zoai:scielo:S1809-98232015000200285Revistahttp://revista.unati.uerj.br/scielo.php?script=sci_serial&pid=1809-9823&lng=pt&nrm=isohttps://old.scielo.br/oai/scielo-oai.php||revistabgg@gmail.com1981-22561809-9823opendoar:2015-07-28T00:00Revista Brasileira de Geriatria e Gerontologia - Universidade do Estado do Rio de Janeiro (UERJ)false |
dc.title.none.fl_str_mv |
Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity |
title |
Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity |
spellingShingle |
Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity Salame,Marcelo Sarcopenia Postmenopause Muscle Strength Calibration Discrimination |
title_short |
Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity |
title_full |
Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity |
title_fullStr |
Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity |
title_full_unstemmed |
Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity |
title_sort |
Sarcopenia: evaluation of different diagnostic criteria and its association with muscle strength and functional capacity |
author |
Salame,Marcelo |
author_facet |
Salame,Marcelo Costa,Karen Koff da Zottele,Lucas Venturini Muradás,Raquel Rodrigues Tierno,Sibelle de Almeida Schettinger,Maria Rosa Chitolina Premaor,Melissa Beck,Maristela de Oliveira |
author_role |
author |
author2 |
Costa,Karen Koff da Zottele,Lucas Venturini Muradás,Raquel Rodrigues Tierno,Sibelle de Almeida Schettinger,Maria Rosa Chitolina Premaor,Melissa Beck,Maristela de Oliveira |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Salame,Marcelo Costa,Karen Koff da Zottele,Lucas Venturini Muradás,Raquel Rodrigues Tierno,Sibelle de Almeida Schettinger,Maria Rosa Chitolina Premaor,Melissa Beck,Maristela de Oliveira |
dc.subject.por.fl_str_mv |
Sarcopenia Postmenopause Muscle Strength Calibration Discrimination |
topic |
Sarcopenia Postmenopause Muscle Strength Calibration Discrimination |
description |
INTRODUCTION: Sarcopenia has been associated with increased morbidity and mortality in older people. However, there is still no consensus about the best diagnostic criteria for it. OBJECTIVE: This study aimed to evaluate different diagnostic criteria of sarcopenia and their relationship with muscle strength and functional capacity. METHODS: A cross-sectional study was carried out in Santa Maria-RS, Brazil. Body composition was measured by dual-energy X-ray absorptiometry (DXA). Physical performance was evaluated by the Timed-get-up-and-go test (TGUG). Muscle strength was measured with a handgrip dynamometer. The proposed criteria of sarcopenia were evaluated as follows: A) appendicular lean mass index (aLM/ht2), cutoffs 5.5 kg/m2, 2SD, 10th percentile, and 20th percentile of young reference; B) a linear regression model was used to adjust appendicular lean mass (aLM) for both height and fat mass, cutoff 20th percentile of elderly. RESULTS: In total, 104 women agreed to participate in the research, 39 young (20 to 40 years) and 65 elderly (over 60 years). The prevalence of sarcopenia varied from 0% to 17.2% according to the diagnostic criteria. Regarding muscle strength, the aLM/ht2 cutoff 10th percentile was the criterion with greater area under the ROC curve. However, there were no criteria with an area under the ROC curve greater than 0.5 when TGUG was the outcome. The reclassification showed that the criterion B reclassified 66.7% with normal grip strength as sarcopenic. CONCLUSION: Of these criteria, aLM/ht2 cutoff 10th percentile had stronger correlation with muscle strength. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-98232015000200285 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-98232015000200285 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1809-9823.2015.14025 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade do Estado do Rio Janeiro |
publisher.none.fl_str_mv |
Universidade do Estado do Rio Janeiro |
dc.source.none.fl_str_mv |
Revista Brasileira de Geriatria e Gerontologia v.18 n.2 2015 reponame:Revista Brasileira de Geriatria e Gerontologia instname:Universidade do Estado do Rio de Janeiro (UERJ) instacron:UFRJ |
instname_str |
Universidade do Estado do Rio de Janeiro (UERJ) |
instacron_str |
UFRJ |
institution |
UFRJ |
reponame_str |
Revista Brasileira de Geriatria e Gerontologia |
collection |
Revista Brasileira de Geriatria e Gerontologia |
repository.name.fl_str_mv |
Revista Brasileira de Geriatria e Gerontologia - Universidade do Estado do Rio de Janeiro (UERJ) |
repository.mail.fl_str_mv |
||revistabgg@gmail.com |
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1750128435450085376 |