The impact of depression on survival of Parkinson's disease patients: a five-year study
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal Brasileiro de Psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852013000100002 |
Resumo: | OBJECTIVE: The aim of this study is to evaluate the survival rate in a cohort of Parkinson's disease patients with and without depression. METHODS: A total of 53 Parkinson's disease subjects were followed up from 2003-2008 and 21 were diagnosed as depressed. Mean time of follow up was 3.8 (SD 95% = 1.5) years for all the sample and there was no significant difference in mean time of follow up between depressed and nondepressed Parkinson's disease patients. Survival curves rates were fitted using the Kaplan-Meier method. In order to compare survival probabilities according to the selected covariables the Log-Rank test was used. Multivariate analysis with Cox regression was performed aiming at estimating the effect of predictive covariables on the survival. RESULTS: The cumulative global survival of this sample was 83% with nine deaths at the end of the study - five in the depressed and four in the nondepressed group, and 55.6% died in the first year of observation, and none died at the fourth and fifth year of follow up. CONCLUSION: Our finding point toward incremental death risk in depressed Parkinson's disease patients. |
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Jornal Brasileiro de Psiquiatria (Online) |
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The impact of depression on survival of Parkinson's disease patients: a five-year studyParkinson's diseasedepressionmortalityOBJECTIVE: The aim of this study is to evaluate the survival rate in a cohort of Parkinson's disease patients with and without depression. METHODS: A total of 53 Parkinson's disease subjects were followed up from 2003-2008 and 21 were diagnosed as depressed. Mean time of follow up was 3.8 (SD 95% = 1.5) years for all the sample and there was no significant difference in mean time of follow up between depressed and nondepressed Parkinson's disease patients. Survival curves rates were fitted using the Kaplan-Meier method. In order to compare survival probabilities according to the selected covariables the Log-Rank test was used. Multivariate analysis with Cox regression was performed aiming at estimating the effect of predictive covariables on the survival. RESULTS: The cumulative global survival of this sample was 83% with nine deaths at the end of the study - five in the depressed and four in the nondepressed group, and 55.6% died in the first year of observation, and none died at the fourth and fifth year of follow up. CONCLUSION: Our finding point toward incremental death risk in depressed Parkinson's disease patients.Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro2013-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852013000100002Jornal Brasileiro de Psiquiatria v.62 n.1 2013reponame:Jornal Brasileiro de Psiquiatria (Online)instname:Universidade Federal do Rio de Janeiro (UFRJ)instacron:UFRJ10.1590/S0047-20852013000100002info:eu-repo/semantics/openAccessSilberman,Cláudia DéboraRodrigues,Cláudia SoaresEngelhardt,EliaszLaks,Jersoneng2013-05-07T00:00:00Zoai:scielo:S0047-20852013000100002Revistahttp://portalrev.enfermagem.bvs.br/index.php?issn=0047-2085&lang=ptONGhttps://old.scielo.br/oai/scielo-oai.php||editora@ipub.ufrj.br1982-02080047-2085opendoar:2013-05-07T00:00Jornal Brasileiro de Psiquiatria (Online) - Universidade Federal do Rio de Janeiro (UFRJ)false |
dc.title.none.fl_str_mv |
The impact of depression on survival of Parkinson's disease patients: a five-year study |
title |
The impact of depression on survival of Parkinson's disease patients: a five-year study |
spellingShingle |
The impact of depression on survival of Parkinson's disease patients: a five-year study Silberman,Cláudia Débora Parkinson's disease depression mortality |
title_short |
The impact of depression on survival of Parkinson's disease patients: a five-year study |
title_full |
The impact of depression on survival of Parkinson's disease patients: a five-year study |
title_fullStr |
The impact of depression on survival of Parkinson's disease patients: a five-year study |
title_full_unstemmed |
The impact of depression on survival of Parkinson's disease patients: a five-year study |
title_sort |
The impact of depression on survival of Parkinson's disease patients: a five-year study |
author |
Silberman,Cláudia Débora |
author_facet |
Silberman,Cláudia Débora Rodrigues,Cláudia Soares Engelhardt,Eliasz Laks,Jerson |
author_role |
author |
author2 |
Rodrigues,Cláudia Soares Engelhardt,Eliasz Laks,Jerson |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Silberman,Cláudia Débora Rodrigues,Cláudia Soares Engelhardt,Eliasz Laks,Jerson |
dc.subject.por.fl_str_mv |
Parkinson's disease depression mortality |
topic |
Parkinson's disease depression mortality |
description |
OBJECTIVE: The aim of this study is to evaluate the survival rate in a cohort of Parkinson's disease patients with and without depression. METHODS: A total of 53 Parkinson's disease subjects were followed up from 2003-2008 and 21 were diagnosed as depressed. Mean time of follow up was 3.8 (SD 95% = 1.5) years for all the sample and there was no significant difference in mean time of follow up between depressed and nondepressed Parkinson's disease patients. Survival curves rates were fitted using the Kaplan-Meier method. In order to compare survival probabilities according to the selected covariables the Log-Rank test was used. Multivariate analysis with Cox regression was performed aiming at estimating the effect of predictive covariables on the survival. RESULTS: The cumulative global survival of this sample was 83% with nine deaths at the end of the study - five in the depressed and four in the nondepressed group, and 55.6% died in the first year of observation, and none died at the fourth and fifth year of follow up. CONCLUSION: Our finding point toward incremental death risk in depressed Parkinson's disease patients. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852013000100002 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852013000100002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0047-20852013000100002 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro |
publisher.none.fl_str_mv |
Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro |
dc.source.none.fl_str_mv |
Jornal Brasileiro de Psiquiatria v.62 n.1 2013 reponame:Jornal Brasileiro de Psiquiatria (Online) instname:Universidade Federal do Rio de Janeiro (UFRJ) instacron:UFRJ |
instname_str |
Universidade Federal do Rio de Janeiro (UFRJ) |
instacron_str |
UFRJ |
institution |
UFRJ |
reponame_str |
Jornal Brasileiro de Psiquiatria (Online) |
collection |
Jornal Brasileiro de Psiquiatria (Online) |
repository.name.fl_str_mv |
Jornal Brasileiro de Psiquiatria (Online) - Universidade Federal do Rio de Janeiro (UFRJ) |
repository.mail.fl_str_mv |
||editora@ipub.ufrj.br |
_version_ |
1750128246138077184 |