A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria

Detalhes bibliográficos
Autor(a) principal: de Uzeda, Milton
Data de Publicação: 2015
Outros Autores: Magalhães, Fernando Antonio da Cunha, Colombo, Ana Paula Vieira, Lima, Kenio Costa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Ciência Plural
Texto Completo: https://periodicos.ufrn.br/rcp/article/view/7319
Resumo: Introduction: Mouthwashes solutions can play an important role in the chemical control of dental biofilm. However, quality control procedures related to antimicrobial activity of these solutions against oral bacteria are not well known. Objective: To evaluate in vivo antimicrobial activity of six mouthwashes solutions available in the Brazilian market against anaerobic salivary bacteria. Material and methods: An in vivo study was developed in human volunteers (8 male and 7 female, ranging from 18 to 63 years old), despite their oral health status. The following commercial products were tested after 2 hours of a single mouthwash procedure: 1) Plax®, 2) Listerine®, 3) Periogard®, 4) Cepacol®, 5) Sanifill Premium® and 6)Oral B®. Data were analyzed by ANOVA to repeated measures and ANOVA one-way with a significance level of 5%. Results: Statistically significant difference (p<0.05) was observed in the decrease of microbial counts to Plax® between baseline (before mouthwash) and immediately after mouthwash (T0); to Periogard® between baseline and T60 (60 minutes after mouthwash), baseline and T120 (120 minutes after mouthwash) and to Oral B® between baseline and T-30 (30 minutes after mouthwash). Periogard® showed the highest and delayed reduction of salivary microbial counts. Conclusion: Out of six tested mouthwashes, Plax®, Oral B® and Periogard ® showed immediate antibacterial activity. Periogard® was the oral anti-septic that showed the best delayed activity against salivary anaerobic bacteria.
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spelling A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteriaESTUDO COMPARATIVO DA ATIVIDADE ANTIMICROBIANA “IN VIVO” DE SEIS ANTISSÉPTICOS BUCAIS SOBRE A MICROBIOTA DA SALIVAMouthwashesSalivaBacteriaAntissépticos BucaisSalivaBactérias.Introduction: Mouthwashes solutions can play an important role in the chemical control of dental biofilm. However, quality control procedures related to antimicrobial activity of these solutions against oral bacteria are not well known. Objective: To evaluate in vivo antimicrobial activity of six mouthwashes solutions available in the Brazilian market against anaerobic salivary bacteria. Material and methods: An in vivo study was developed in human volunteers (8 male and 7 female, ranging from 18 to 63 years old), despite their oral health status. The following commercial products were tested after 2 hours of a single mouthwash procedure: 1) Plax®, 2) Listerine®, 3) Periogard®, 4) Cepacol®, 5) Sanifill Premium® and 6)Oral B®. Data were analyzed by ANOVA to repeated measures and ANOVA one-way with a significance level of 5%. Results: Statistically significant difference (p<0.05) was observed in the decrease of microbial counts to Plax® between baseline (before mouthwash) and immediately after mouthwash (T0); to Periogard® between baseline and T60 (60 minutes after mouthwash), baseline and T120 (120 minutes after mouthwash) and to Oral B® between baseline and T-30 (30 minutes after mouthwash). Periogard® showed the highest and delayed reduction of salivary microbial counts. Conclusion: Out of six tested mouthwashes, Plax®, Oral B® and Periogard ® showed immediate antibacterial activity. Periogard® was the oral anti-septic that showed the best delayed activity against salivary anaerobic bacteria.Introdução: Soluções de antissépticos bucais podem desempenhar importante papel no controle químico do biofilme dentário. No entanto, os procedimentos de controle de qualidade relacionados com a atividade antimicrobiana destes enxaguatórios contra bactérias da cavidade oral não são bem divulgados. Objetivo: Avaliar a atividade antimicrobiana in vivo de seis soluções de antissépticos bucais disponíveis no mercado brasileiro, empregadas como enxaguatórios contra bactérias da saliva humana. Material e métodos: Um estudo in vivo foi desenvolvido com indivíduos voluntários (8 do sexo masculino e 7 do sexo feminino, variando de 18 a 63 anos de idade ), independente do estado de saúde bucal. Os seguintes produtos comerciais foram testados durante 2 horas após um único procedimento de bochecho: 1) Plax®, 2) Listerine®, 3) Periogard®, 4) Cepacol®, 5) Sanifill Premium® e 6) Oral B®.Os resultados foram analisados pelo teste de ANOVA de medidas repetidas e ANOVA one-way com um nível de significância de 5%. Resultados: Houve diferença significativa (p <0,05) observada na diminuição da carga microbiana para Plax® entre o início (antes anti-séptico bucal) e imediatamente após o bochecho (T0); para Periogard® entre os valores iniciais e T60 (60 minutos após o bochecho), na linha de base e16Revista Ciência Plural, 2015; 1(1): 15-21.T120 (120 minutos após o bochecho) e B® Oral entre os valores iniciais e T-30 (30 minutos após o bochecho). Periogard® apresentou a maior redução da carga microbiana salivares. Conclusão: Dos seis bochechos testados, Plax®, Oral B® e Periogard ® apresentou atividade antibacteriana imediata. Periogard® foi o anti-séptico bucal que mostrou a atividade mais prolongada contra bactérias anaeróbias salivares.Portal de Periódicos Eletrônicos da UFRN2015-04-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArtigo avaliado pelos Paresapplication/pdfhttps://periodicos.ufrn.br/rcp/article/view/7319Revista Ciência Plural; v. 1 n. 1 (2015); 15-212446-7286reponame:Revista Ciência Pluralinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNporhttps://periodicos.ufrn.br/rcp/article/view/7319/5496Copyright (c) 2015 Revista Ciência Pluralinfo:eu-repo/semantics/openAccessde Uzeda, MiltonMagalhães, Fernando Antonio da CunhaColombo, Ana Paula VieiraLima, Kenio Costa2015-08-13T19:05:09Zoai:periodicos.ufrn.br:article/7319Revistahttps://periodicos.ufrn.br/rcpPUBhttps://periodicos.ufrn.br/rcp/oai||irisdoceu.ufrn@gmail.com2446-72862446-7286opendoar:2015-08-13T19:05:09Revista Ciência Plural - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.none.fl_str_mv A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria
ESTUDO COMPARATIVO DA ATIVIDADE ANTIMICROBIANA “IN VIVO” DE SEIS ANTISSÉPTICOS BUCAIS SOBRE A MICROBIOTA DA SALIVA
title A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria
spellingShingle A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria
de Uzeda, Milton
Mouthwashes
Saliva
Bacteria
Antissépticos Bucais
Saliva
Bactérias.
title_short A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria
title_full A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria
title_fullStr A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria
title_full_unstemmed A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria
title_sort A comparative in vivo study of antimicrobial activity of six commercial mouthwashes against salivary bacteria
author de Uzeda, Milton
author_facet de Uzeda, Milton
Magalhães, Fernando Antonio da Cunha
Colombo, Ana Paula Vieira
Lima, Kenio Costa
author_role author
author2 Magalhães, Fernando Antonio da Cunha
Colombo, Ana Paula Vieira
Lima, Kenio Costa
author2_role author
author
author
dc.contributor.author.fl_str_mv de Uzeda, Milton
Magalhães, Fernando Antonio da Cunha
Colombo, Ana Paula Vieira
Lima, Kenio Costa
dc.subject.por.fl_str_mv Mouthwashes
Saliva
Bacteria
Antissépticos Bucais
Saliva
Bactérias.
topic Mouthwashes
Saliva
Bacteria
Antissépticos Bucais
Saliva
Bactérias.
description Introduction: Mouthwashes solutions can play an important role in the chemical control of dental biofilm. However, quality control procedures related to antimicrobial activity of these solutions against oral bacteria are not well known. Objective: To evaluate in vivo antimicrobial activity of six mouthwashes solutions available in the Brazilian market against anaerobic salivary bacteria. Material and methods: An in vivo study was developed in human volunteers (8 male and 7 female, ranging from 18 to 63 years old), despite their oral health status. The following commercial products were tested after 2 hours of a single mouthwash procedure: 1) Plax®, 2) Listerine®, 3) Periogard®, 4) Cepacol®, 5) Sanifill Premium® and 6)Oral B®. Data were analyzed by ANOVA to repeated measures and ANOVA one-way with a significance level of 5%. Results: Statistically significant difference (p<0.05) was observed in the decrease of microbial counts to Plax® between baseline (before mouthwash) and immediately after mouthwash (T0); to Periogard® between baseline and T60 (60 minutes after mouthwash), baseline and T120 (120 minutes after mouthwash) and to Oral B® between baseline and T-30 (30 minutes after mouthwash). Periogard® showed the highest and delayed reduction of salivary microbial counts. Conclusion: Out of six tested mouthwashes, Plax®, Oral B® and Periogard ® showed immediate antibacterial activity. Periogard® was the oral anti-septic that showed the best delayed activity against salivary anaerobic bacteria.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-23
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Artigo avaliado pelos Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.ufrn.br/rcp/article/view/7319
url https://periodicos.ufrn.br/rcp/article/view/7319
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufrn.br/rcp/article/view/7319/5496
dc.rights.driver.fl_str_mv Copyright (c) 2015 Revista Ciência Plural
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2015 Revista Ciência Plural
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Portal de Periódicos Eletrônicos da UFRN
publisher.none.fl_str_mv Portal de Periódicos Eletrônicos da UFRN
dc.source.none.fl_str_mv Revista Ciência Plural; v. 1 n. 1 (2015); 15-21
2446-7286
reponame:Revista Ciência Plural
instname:Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
instname_str Universidade Federal do Rio Grande do Norte (UFRN)
instacron_str UFRN
institution UFRN
reponame_str Revista Ciência Plural
collection Revista Ciência Plural
repository.name.fl_str_mv Revista Ciência Plural - Universidade Federal do Rio Grande do Norte (UFRN)
repository.mail.fl_str_mv ||irisdoceu.ufrn@gmail.com
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