Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics

Detalhes bibliográficos
Autor(a) principal: Dias Rodrigues Araújo, Rebeca
Data de Publicação: 2022
Outros Autores: Porto de Melo, Rodolfo, Nunes Alves de Sousa, Milena
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Ciência Plural
Texto Completo: https://periodicos.ufrn.br/rcp/article/view/27697
Resumo: Introduction: Anorexia nervosa is characterized by an eating disorder with a typical clinical of food restriction and malnutrition. Objective: to verify the effectiveness of the use of the antipsychotic drugs olanzapine, quetiapine, risperidone in the weight gain of patients with this pathology. Methodology: 9 Randomized Clinical Trials (RCT) were used attached to the Medical Literature Analysis and Retrieval System Online/PubMed (MEDLINE) platform, all of which were analyzed based on inclusion and exclusion criteria made in pairs to carry out a Systematic Literature Review. Results: articles were evaluated through the Grading of Recommendatons Assessment Development and Evaluaton (GRADE) system. Discussion: Thus, among the main findings, the antipsychotic olanzapine appears as the most promising among risperidone and quetiapine. It has a positive effect on increasing the Body Mass Index (BMI) for a shorter period of time according to the Randomized Clinical Trials (RCT). Conclusions:  further studies it is still needed to expand the field of treatment of eating disorders. Keywords: Eating disorder. Anorexia nervosa. Antipsychotics.
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spelling Anorexia nervosa and the effect on the clinical framework with the use of antipsychoticsAnorexia nervosa y el efecto sobre el marco clínico con el uso de antipsicóticosANOREXIA NERVOSA E O EFEITO NO QUADRO CLÍNICO COM O USO DOS ANTIPSICÓTICOS Introduction: Anorexia nervosa is characterized by an eating disorder with a typical clinical of food restriction and malnutrition. Objective: to verify the effectiveness of the use of the antipsychotic drugs olanzapine, quetiapine, risperidone in the weight gain of patients with this pathology. Methodology: 9 Randomized Clinical Trials (RCT) were used attached to the Medical Literature Analysis and Retrieval System Online/PubMed (MEDLINE) platform, all of which were analyzed based on inclusion and exclusion criteria made in pairs to carry out a Systematic Literature Review. Results: articles were evaluated through the Grading of Recommendatons Assessment Development and Evaluaton (GRADE) system. Discussion: Thus, among the main findings, the antipsychotic olanzapine appears as the most promising among risperidone and quetiapine. It has a positive effect on increasing the Body Mass Index (BMI) for a shorter period of time according to the Randomized Clinical Trials (RCT). Conclusions:  further studies it is still needed to expand the field of treatment of eating disorders. Keywords: Eating disorder. Anorexia nervosa. Antipsychotics.Introducción: La anorexia nerviosa se caracteriza por un trastorno alimentario con un cuadro clínico típico de restricción alimentaria y desnutrición. Objetivo: verificar la efectividad del uso de los medicamentos antipsicóticos olanzapina, quetiapina, risperidona em el aumento de peso de pacientes con esta patología. Metodología: Se utilizaron 9 Ensayos Clínicos Aleatorizados (RCT) adjuntos a la plataforma Medical Literature Analysis and Retrieval System Online / PubMed (MEDLINE), todos fueron analizados en base a criterios de inclusión y exclusión realizados en pares para realizar una Revisión Sistemática de la Literatura. Resultados: Los artículos fueron evaluados mediante el sistema Grading of Recommendatons Assessment Development and Evaluaton (GRADE). Discusión: Así, entre los principales hallazgos, el antipsicótico olanzapina aparece como el más prometedor entre la risperidona y la quetiapina. Tiene un efecto positivo en el aumento del índice de masa corporal (IMC) durante un período de tiempo más corto de acuerdo con los ensayos clínicos aleatorizados (RCT). Conclusiones: aun es necesario más estudios para ampliar el campo del tratamiento de los trastornos alimentarios. Palabras clave: Desorden alimenticio. Anorexia nerviosa. Antipsicóticos.Introdução: a anorexia nervosa caracteriza-se por um transtorno alimentar com quadro clínico típico de restrição dietética e desnutrição. Objetivo: verificar a eficácia do uso dos fármacos antipsicóticos olanzapina, quetiapina, risperidona no aumento ponderal de pacientes com tal patologia. Metodologia: utilizou-se de 9 Ensaios Clínicos Randomizados (ECR) anexados na plataforma Medical Literature Analysis and Retrieval System Online/PubMed (MEDLINE), sendo todos analisados a partir de critérios de inclusão e exclusão feitos aos pares para a realização de uma Revisão Sistemática de Literatura. Resultados: os artigos foram avaliados através do sistema Grading of Recommendatons Assessment Development and Evaluaton (GRADE). Discussão: desse modo, dentre os principais achados, o antipsicótico olanzapina aparece como o mais promissor entre a risperidona e a quetiapina. O mesmo apresenta efeito positivo no aumento do Índice de Massa Corpórea (IMC) durante um menor intervalo de tempo de acordo com os Ensaios Clínicos Randomizados (ECR). Conclusões: ainda se faz necessários novos estudos para ampliar o campo de tratamento dos transtornos alimentares. Palavras-Chave: Transtorno alimentar. Anorexia nervosa. Antipsicóticos.Portal de Periódicos Eletrônicos da UFRN2022-03-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.ufrn.br/rcp/article/view/2769710.21680/2446-7286.2022v8n2ID27697Revista Ciência Plural; v. 8 n. 2 (2022): Revista Ciência Plural; 1-122446-728610.21680/2446-7286.2022v8n2reponame:Revista Ciência Pluralinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNporhttps://periodicos.ufrn.br/rcp/article/view/27697/15422Copyright (c) 2022 Revista Ciência Pluralinfo:eu-repo/semantics/openAccessDias Rodrigues Araújo, RebecaPorto de Melo, RodolfoNunes Alves de Sousa, Milena2022-03-25T03:18:45Zoai:periodicos.ufrn.br:article/27697Revistahttps://periodicos.ufrn.br/rcpPUBhttps://periodicos.ufrn.br/rcp/oai||irisdoceu.ufrn@gmail.com2446-72862446-7286opendoar:2022-03-25T03:18:45Revista Ciência Plural - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.none.fl_str_mv Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics
Anorexia nervosa y el efecto sobre el marco clínico con el uso de antipsicóticos
ANOREXIA NERVOSA E O EFEITO NO QUADRO CLÍNICO COM O USO DOS ANTIPSICÓTICOS
title Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics
spellingShingle Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics
Dias Rodrigues Araújo, Rebeca
title_short Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics
title_full Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics
title_fullStr Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics
title_full_unstemmed Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics
title_sort Anorexia nervosa and the effect on the clinical framework with the use of antipsychotics
author Dias Rodrigues Araújo, Rebeca
author_facet Dias Rodrigues Araújo, Rebeca
Porto de Melo, Rodolfo
Nunes Alves de Sousa, Milena
author_role author
author2 Porto de Melo, Rodolfo
Nunes Alves de Sousa, Milena
author2_role author
author
dc.contributor.author.fl_str_mv Dias Rodrigues Araújo, Rebeca
Porto de Melo, Rodolfo
Nunes Alves de Sousa, Milena
description Introduction: Anorexia nervosa is characterized by an eating disorder with a typical clinical of food restriction and malnutrition. Objective: to verify the effectiveness of the use of the antipsychotic drugs olanzapine, quetiapine, risperidone in the weight gain of patients with this pathology. Methodology: 9 Randomized Clinical Trials (RCT) were used attached to the Medical Literature Analysis and Retrieval System Online/PubMed (MEDLINE) platform, all of which were analyzed based on inclusion and exclusion criteria made in pairs to carry out a Systematic Literature Review. Results: articles were evaluated through the Grading of Recommendatons Assessment Development and Evaluaton (GRADE) system. Discussion: Thus, among the main findings, the antipsychotic olanzapine appears as the most promising among risperidone and quetiapine. It has a positive effect on increasing the Body Mass Index (BMI) for a shorter period of time according to the Randomized Clinical Trials (RCT). Conclusions:  further studies it is still needed to expand the field of treatment of eating disorders. Keywords: Eating disorder. Anorexia nervosa. Antipsychotics.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-08
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.ufrn.br/rcp/article/view/27697
10.21680/2446-7286.2022v8n2ID27697
url https://periodicos.ufrn.br/rcp/article/view/27697
identifier_str_mv 10.21680/2446-7286.2022v8n2ID27697
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufrn.br/rcp/article/view/27697/15422
dc.rights.driver.fl_str_mv Copyright (c) 2022 Revista Ciência Plural
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Revista Ciência Plural
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Portal de Periódicos Eletrônicos da UFRN
publisher.none.fl_str_mv Portal de Periódicos Eletrônicos da UFRN
dc.source.none.fl_str_mv Revista Ciência Plural; v. 8 n. 2 (2022): Revista Ciência Plural; 1-12
2446-7286
10.21680/2446-7286.2022v8n2
reponame:Revista Ciência Plural
instname:Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
instname_str Universidade Federal do Rio Grande do Norte (UFRN)
instacron_str UFRN
institution UFRN
reponame_str Revista Ciência Plural
collection Revista Ciência Plural
repository.name.fl_str_mv Revista Ciência Plural - Universidade Federal do Rio Grande do Norte (UFRN)
repository.mail.fl_str_mv ||irisdoceu.ufrn@gmail.com
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