CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Ciência Plural |
Texto Completo: | https://periodicos.ufrn.br/rcp/article/view/27811 |
Resumo: | Introduction: Childhood cancer corresponds to a group of several diseases that have in common the uncontrolled proliferation of abnormal cells and that can occur anywhere in the body. Neoplasms that affect children and adolescents should be studied separately, as they differ from tumors that affect adults. Objective: Identify the most frequent types of neoplasms in childhood and adolescence and analyze the clinical-epidemiological profile of patients. Methodology: Exploratory cross-sectional study, applied in nature with document analysis, carried out at the Pediatric Oncohematology Center of the Oswaldo Cruz University Hospital (CEONHPE-HUOC). Children and adolescents diagnosed with neoplasia and treated with antineoplastic therapy were included. Exclusion criteria were normoreactive children and adolescents and/or with systemic diseases; illegible medical records or lacking clinical information. Results: It was identified that 54.21% of the patients were female, followed by 44.86% male and only 0.93% did not respond or were not identified. The prevalent age group in the study was children from 5 to 14 years old (54.21%), still regarding the profile of the patients, it was identified that the population self-declared as black was the most prevalent, representing 44.86% of the total, followed by of whites with 43.93%. The diagnosis that prevailed was Acute Lymphoid Leukemia (ALL) (23.36%), followed by Retinoblastoma (7.48%) and Embryonic Rhabdomyosarcoma (6.54%), and consequently the site of the primary neoplasm that prevailed was Bone marrow (27.10%) followed by the eye (10.28%), of this total it is noted that the most used anticancer treatment was chemotherapy (40.19%) followed by chemotherapy associated with radiotherapy (12.15% ) and chemotherapy associated with surgery (10.28%). Conclusions: Acute lymphoblastic leukemia was the most frequent neoplasm in childhood and adolescence, with a prevalence between 5 and 14 years of age, in females and in black ethnicity. The most used antineoplastic therapy was chemotherapy, followed by the association between chemotherapy and radiotherapy. |
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CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCOPERFIL CLÍNICO-EPIDEMIOLÓGICO DE PACIENTES ONCOLÓGICOS PEDIÁTRICOS EN UN CENTRO DE ONCOHEMATOLOGÍA DE PERNAMBUCOPERFIL CLÍNICO-EPIDEMIOLÓGICO DE PACIENTES PEDIÁTRICOS DE UM CENTRO DE ONCOHEMATOLOGIA DE PERNAMBUCOIntroduction: Childhood cancer corresponds to a group of several diseases that have in common the uncontrolled proliferation of abnormal cells and that can occur anywhere in the body. Neoplasms that affect children and adolescents should be studied separately, as they differ from tumors that affect adults. Objective: Identify the most frequent types of neoplasms in childhood and adolescence and analyze the clinical-epidemiological profile of patients. Methodology: Exploratory cross-sectional study, applied in nature with document analysis, carried out at the Pediatric Oncohematology Center of the Oswaldo Cruz University Hospital (CEONHPE-HUOC). Children and adolescents diagnosed with neoplasia and treated with antineoplastic therapy were included. Exclusion criteria were normoreactive children and adolescents and/or with systemic diseases; illegible medical records or lacking clinical information. Results: It was identified that 54.21% of the patients were female, followed by 44.86% male and only 0.93% did not respond or were not identified. The prevalent age group in the study was children from 5 to 14 years old (54.21%), still regarding the profile of the patients, it was identified that the population self-declared as black was the most prevalent, representing 44.86% of the total, followed by of whites with 43.93%. The diagnosis that prevailed was Acute Lymphoid Leukemia (ALL) (23.36%), followed by Retinoblastoma (7.48%) and Embryonic Rhabdomyosarcoma (6.54%), and consequently the site of the primary neoplasm that prevailed was Bone marrow (27.10%) followed by the eye (10.28%), of this total it is noted that the most used anticancer treatment was chemotherapy (40.19%) followed by chemotherapy associated with radiotherapy (12.15% ) and chemotherapy associated with surgery (10.28%). Conclusions: Acute lymphoblastic leukemia was the most frequent neoplasm in childhood and adolescence, with a prevalence between 5 and 14 years of age, in females and in black ethnicity. The most used antineoplastic therapy was chemotherapy, followed by the association between chemotherapy and radiotherapy.Introducción: El cáncer infantil corresponde a un grupo de varias enfermedades que tienen en común la proliferación descontrolada de células anormales y que pueden presentarse en cualquier parte del cuerpo. Las neoplasias que afectan a niños y adolescentes deben estudiarse por separado, ya que difieren de los tumores que afectan a los adultos. Objetivo: Identificar los tipos de neoplasias más frecuentes en la infancia y la adolescencia y analizar el perfil clínico-epidemiológico de los pacientes. Metodología: Estudio transversal exploratorio, aplicado en la naturaleza con análisis de documentos, realizado en el Centro de Oncohematología Pediátrica del Hospital Universitario Oswaldo Cruz (CEONHPE-HUOC). Se incluyeron niños y adolescentes con diagnóstico de neoplasia y tratados con terapia antineoplásica. Los criterios de exclusión fueron niños y adolescentes normorreactivos y/o con enfermedades sistémicas; registros médicos ilegibles o carentes de información clínica. Resultados: Se identificó que el 54,21% de los pacientes eran del sexo femenino, seguido del 44,86% del masculino y solo el 0,93% no respondieron o no fueron identificados. El grupo etario prevalente en el estudio fueron los niños de 5 a 14 años (54,21%), aún en cuanto al perfil de los pacientes, se identificó que la población autodeclarada negra fue la más prevalente, representando el 44,86% del total , seguido de los blancos con un 43,93%. El diagnóstico que predominó fue Leucemia Linfoide Aguda (LLA) (23,36%), seguido de Retinoblastoma (7,48%) y Rabdomiosarcoma Embrionario (6,54%), y en consecuencia el sitio de la neoplasia primaria que predominó fue Médula Ósea (27,10%) seguido de ocular (10,28 %), de este total se destaca que el tratamiento anticancerígeno más utilizado fue la quimioterapia (40,19 %) seguida de la quimioterapia asociada a radioterapia (12,15 %) y la quimioterapia asociada a cirugía (10,28 %). Conclusiones: La leucemia linfoblástica aguda fue la neoplasia más frecuente en la infancia y la adolescencia, con prevalencia entre los 5 y los 14 años, en el sexo femenino y en la etnia negra. La terapia antineoplásica más utilizada fue la quimioterapia, seguida de la asociación entre quimioterapia y radioterapia.Introdução: O câncer infantojuvenil corresponde a um grupo de várias doenças que têm em comum a proliferação descontrolada de células anormais e que pode ocorrer em qualquer local do organismo. As neoplasias que acometem crianças e adolescentes devem ser estudadas separadamente, pois estas diferem dos tumores que acometem os adultos. Objetivo: Identificar os tipos de neoplasias mais frequentes na infância e adolescência e analisar o perfil clínico-epidemiológico dos pacientes. Metodologia: Estudo de transversal exploratório, de natureza aplicada com análise documental, realizado no Centro de Oncohematologia Pediátrica do Hospital Universitário Oswaldo Cruz (CEONHPE-HUOC). Foram incluídos crianças e adolescentes diagnosticados com neoplasia e tratados por terapia antineoplásica. Os critérios de exclusão foram crianças e adolescentes normorreativas e/ou com doenças sistêmicas; prontuários ilegíveis ou com falta de informações clínicas. Resultados: Identificou-se que 54,21% dos pacientes eram do sexo feminino, seguido por 44,86% do sexo masculino e apenas 0,93% não responderam ou não tiveram o sexo identificado. A faixa etária prevalente no estudo foi o de crianças de 5 a 14 anos (54,21%), ainda sobre o perfil dos pacientes, identificou-se que população autodeclarada como negra foi a mais prevalente representando 44,86% do total, seguido dos brancos com 43,93%. O diagnóstico que prevaleceu foi o de Leucemia Linfoide Aguda (LLA) (23,36%), seguido pela Retinoblastoma (7,48%) e pela Rabdomiossarcoma embrionário (6,54%), e consequentemente o local da neoplasia primária que prevaleceu foi a Medula óssea (27,10%) seguido do olho (10,28%), deste total nota-se que o tratamento antineoplásico mais utilizado foi a quimioterapia (40,19%) seguido da quimioterapia associada à radioterapia (12,15%) e pela quimioterapia associada a cirurgia (10,28%). Conclusões: A leucemia linfoide aguda foi a neoplasia mais frequente na infância e adolescência, com prevalência na idade entre 5 e 14 anos, no sexo feminino e na etnia negra. A terapia antineoplásica mais utilizada foi a quimioterapia, seguida da associação entre quimioterapia e radioterapia.Portal de Periódicos Eletrônicos da UFRN2023-04-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.ufrn.br/rcp/article/view/2781110.21680/2446-7286.2023v9n1ID27811Revista Ciência Plural; v. 9 n. 1 (2023): Revista Ciência Plural; 1-132446-728610.21680/2446-7286.2023v9n1reponame:Revista Ciência Pluralinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNporhttps://periodicos.ufrn.br/rcp/article/view/27811/16828Copyright (c) 2023 Revista Ciência Pluralhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessLaiza Candido da Silva, GabrielaCarlos Rodrigues de Almeida, HíttaloFonseca da Silveira, Márcia MariaVeras Sobral, Ana Paula2023-04-28T01:38:11Zoai:periodicos.ufrn.br:article/27811Revistahttps://periodicos.ufrn.br/rcpPUBhttps://periodicos.ufrn.br/rcp/oai||irisdoceu.ufrn@gmail.com2446-72862446-7286opendoar:2023-04-28T01:38:11Revista Ciência Plural - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.none.fl_str_mv |
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO PERFIL CLÍNICO-EPIDEMIOLÓGICO DE PACIENTES ONCOLÓGICOS PEDIÁTRICOS EN UN CENTRO DE ONCOHEMATOLOGÍA DE PERNAMBUCO PERFIL CLÍNICO-EPIDEMIOLÓGICO DE PACIENTES PEDIÁTRICOS DE UM CENTRO DE ONCOHEMATOLOGIA DE PERNAMBUCO |
title |
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO |
spellingShingle |
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO Laiza Candido da Silva, Gabriela |
title_short |
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO |
title_full |
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO |
title_fullStr |
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO |
title_full_unstemmed |
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO |
title_sort |
CLINICAL-EPIDEMIOLOGICAL PROFILE OF PEDIATRIC ONCOLOGICAL PATIENTS AT A CENTER OF ONCOHEMATOLOGY IN PERNAMBUCO |
author |
Laiza Candido da Silva, Gabriela |
author_facet |
Laiza Candido da Silva, Gabriela Carlos Rodrigues de Almeida, Híttalo Fonseca da Silveira, Márcia Maria Veras Sobral, Ana Paula |
author_role |
author |
author2 |
Carlos Rodrigues de Almeida, Híttalo Fonseca da Silveira, Márcia Maria Veras Sobral, Ana Paula |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Laiza Candido da Silva, Gabriela Carlos Rodrigues de Almeida, Híttalo Fonseca da Silveira, Márcia Maria Veras Sobral, Ana Paula |
description |
Introduction: Childhood cancer corresponds to a group of several diseases that have in common the uncontrolled proliferation of abnormal cells and that can occur anywhere in the body. Neoplasms that affect children and adolescents should be studied separately, as they differ from tumors that affect adults. Objective: Identify the most frequent types of neoplasms in childhood and adolescence and analyze the clinical-epidemiological profile of patients. Methodology: Exploratory cross-sectional study, applied in nature with document analysis, carried out at the Pediatric Oncohematology Center of the Oswaldo Cruz University Hospital (CEONHPE-HUOC). Children and adolescents diagnosed with neoplasia and treated with antineoplastic therapy were included. Exclusion criteria were normoreactive children and adolescents and/or with systemic diseases; illegible medical records or lacking clinical information. Results: It was identified that 54.21% of the patients were female, followed by 44.86% male and only 0.93% did not respond or were not identified. The prevalent age group in the study was children from 5 to 14 years old (54.21%), still regarding the profile of the patients, it was identified that the population self-declared as black was the most prevalent, representing 44.86% of the total, followed by of whites with 43.93%. The diagnosis that prevailed was Acute Lymphoid Leukemia (ALL) (23.36%), followed by Retinoblastoma (7.48%) and Embryonic Rhabdomyosarcoma (6.54%), and consequently the site of the primary neoplasm that prevailed was Bone marrow (27.10%) followed by the eye (10.28%), of this total it is noted that the most used anticancer treatment was chemotherapy (40.19%) followed by chemotherapy associated with radiotherapy (12.15% ) and chemotherapy associated with surgery (10.28%). Conclusions: Acute lymphoblastic leukemia was the most frequent neoplasm in childhood and adolescence, with a prevalence between 5 and 14 years of age, in females and in black ethnicity. The most used antineoplastic therapy was chemotherapy, followed by the association between chemotherapy and radiotherapy. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-04-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufrn.br/rcp/article/view/27811 10.21680/2446-7286.2023v9n1ID27811 |
url |
https://periodicos.ufrn.br/rcp/article/view/27811 |
identifier_str_mv |
10.21680/2446-7286.2023v9n1ID27811 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.ufrn.br/rcp/article/view/27811/16828 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Revista Ciência Plural https://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Revista Ciência Plural https://creativecommons.org/licenses/by-nc-sa/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Portal de Periódicos Eletrônicos da UFRN |
publisher.none.fl_str_mv |
Portal de Periódicos Eletrônicos da UFRN |
dc.source.none.fl_str_mv |
Revista Ciência Plural; v. 9 n. 1 (2023): Revista Ciência Plural; 1-13 2446-7286 10.21680/2446-7286.2023v9n1 reponame:Revista Ciência Plural instname:Universidade Federal do Rio Grande do Norte (UFRN) instacron:UFRN |
instname_str |
Universidade Federal do Rio Grande do Norte (UFRN) |
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UFRN |
institution |
UFRN |
reponame_str |
Revista Ciência Plural |
collection |
Revista Ciência Plural |
repository.name.fl_str_mv |
Revista Ciência Plural - Universidade Federal do Rio Grande do Norte (UFRN) |
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||irisdoceu.ufrn@gmail.com |
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