Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study

Detalhes bibliográficos
Autor(a) principal: Souza, Dyego Leandro Bezerra de
Data de Publicação: 2023
Outros Autores: Salvans, Anna Escribà, Fochs, Sandra Rierola, Godayol, Pau Farrés, Tuneu, Miriam Molas, Skelton, Dawn A., Roura, Ester Goutan, Molina, Eduard Minobes, Roig, Javier Jerez
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRN
Texto Completo: https://repositorio.ufrn.br/handle/123456789/54655
Resumo: Objectives: To identify which risk factors were associated with developing Coronavirus Disease-19 (COVID-19) infection, with symptoms, in institutionalized older people. Methods: A 1-year longitudinal multi-center study was conducted in 5 nursing homes (NHs) over the period December 2019 to March 2021. Inclusion criteria included being a permanent resident in the NH, aged 65 years or older, and a positive diagnosis of COVID-19 objectively confirmed by a diagnostic test. A descriptive and bivariate analysis was performed, calculating relative risk (RR) with 95% confidence intervals and statistical significance at p<0.05. Results: Of the total sample of 78 individuals who tested positive for COVID-19, the mean age was 84.6 years (SD=±7.8), 62 (79.5%) were female; 40 (51.3%) participants presented with COVID-19 symptoms. Living in a private NH (RR=3.6, 95% CI [1.2-11.0], p=0.023) and having suffered a stroke (RR=4.1, 95% CI [1.1-14.7], p=0.033) were positively associated with developing COVID-19 infection with symptoms. Conclusions: Having suffered a stroke and living permanently in a private NH were positively associated with symptomatic COVID-19 in this sample of institutionalized older people. Clinical Trials ID: NCT04297904
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spelling Souza, Dyego Leandro Bezerra deSalvans, Anna EscribàFochs, Sandra RierolaGodayol, Pau FarrésTuneu, Miriam MolasSkelton, Dawn A.Roura, Ester GoutanMolina, Eduard MinobesRoig, Javier Jerez2023-09-01T15:38:47Z2023-09-01T15:38:47Z2023SOUZA, Dyego Leandro Bezerra de; ESCRIBÀ-SALVANS, Anna; RIEROLA-FOCHS, Sandra; FARRÉS-GODAYOL, Pau; MOLAS-TUNEU, Miriam; SKELTON, Dawn A.; GOUTAN-ROURA, Ester; MINOBES-MOLINA, Eduard; JEREZ-ROIG, Javier. Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesis-generating observational study. Journal Of Frailty, Sarcopenia And Falls, [S.L.], v. 8, n. 2, p. 74-82, 1 jun. 2023. Hylonome Publications. http://dx.doi.org/10.22540/jfsf-08-074. Disponível em: https://www.jfsf.eu/Article.php?AID=v08i02_074. Acesso em: 30 ago. 2023.e2459-4148https://repositorio.ufrn.br/handle/123456789/5465510.22540/JFSF-08-074Journal Of Frailty, Sarcopenia And FallsAttribution-NonCommercial-ShareAlike 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-sa/3.0/br/info:eu-repo/semantics/openAccessCOVID-19geriatric medicineinfectious diseasenursing careRisk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleObjectives: To identify which risk factors were associated with developing Coronavirus Disease-19 (COVID-19) infection, with symptoms, in institutionalized older people. Methods: A 1-year longitudinal multi-center study was conducted in 5 nursing homes (NHs) over the period December 2019 to March 2021. Inclusion criteria included being a permanent resident in the NH, aged 65 years or older, and a positive diagnosis of COVID-19 objectively confirmed by a diagnostic test. A descriptive and bivariate analysis was performed, calculating relative risk (RR) with 95% confidence intervals and statistical significance at p<0.05. Results: Of the total sample of 78 individuals who tested positive for COVID-19, the mean age was 84.6 years (SD=±7.8), 62 (79.5%) were female; 40 (51.3%) participants presented with COVID-19 symptoms. Living in a private NH (RR=3.6, 95% CI [1.2-11.0], p=0.023) and having suffered a stroke (RR=4.1, 95% CI [1.1-14.7], p=0.033) were positively associated with developing COVID-19 infection with symptoms. Conclusions: Having suffered a stroke and living permanently in a private NH were positively associated with symptomatic COVID-19 in this sample of institutionalized older people. Clinical Trials ID: NCT04297904engreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALRiskFactorsDeveloping_Souza_2023.pdfRiskFactorsDeveloping_Souza_2023.pdfapplication/pdf316677https://repositorio.ufrn.br/bitstream/123456789/54655/1/RiskFactorsDeveloping_Souza_2023.pdfdc9a0c498082d7c9cdbf0eb378cf3bc6MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81037https://repositorio.ufrn.br/bitstream/123456789/54655/2/license_rdf996f8b5afe3136b76594f43bfda24c5eMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/54655/3/license.txte9597aa2854d128fd968be5edc8a28d9MD53123456789/546552023-09-01 12:38:48.451oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2023-09-01T15:38:48Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.pt_BR.fl_str_mv Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study
title Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study
spellingShingle Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study
Souza, Dyego Leandro Bezerra de
COVID-19
geriatric medicine
infectious disease
nursing care
title_short Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study
title_full Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study
title_fullStr Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study
title_full_unstemmed Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study
title_sort Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesisgenerating observational study
author Souza, Dyego Leandro Bezerra de
author_facet Souza, Dyego Leandro Bezerra de
Salvans, Anna Escribà
Fochs, Sandra Rierola
Godayol, Pau Farrés
Tuneu, Miriam Molas
Skelton, Dawn A.
Roura, Ester Goutan
Molina, Eduard Minobes
Roig, Javier Jerez
author_role author
author2 Salvans, Anna Escribà
Fochs, Sandra Rierola
Godayol, Pau Farrés
Tuneu, Miriam Molas
Skelton, Dawn A.
Roura, Ester Goutan
Molina, Eduard Minobes
Roig, Javier Jerez
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Souza, Dyego Leandro Bezerra de
Salvans, Anna Escribà
Fochs, Sandra Rierola
Godayol, Pau Farrés
Tuneu, Miriam Molas
Skelton, Dawn A.
Roura, Ester Goutan
Molina, Eduard Minobes
Roig, Javier Jerez
dc.subject.por.fl_str_mv COVID-19
geriatric medicine
infectious disease
nursing care
topic COVID-19
geriatric medicine
infectious disease
nursing care
description Objectives: To identify which risk factors were associated with developing Coronavirus Disease-19 (COVID-19) infection, with symptoms, in institutionalized older people. Methods: A 1-year longitudinal multi-center study was conducted in 5 nursing homes (NHs) over the period December 2019 to March 2021. Inclusion criteria included being a permanent resident in the NH, aged 65 years or older, and a positive diagnosis of COVID-19 objectively confirmed by a diagnostic test. A descriptive and bivariate analysis was performed, calculating relative risk (RR) with 95% confidence intervals and statistical significance at p<0.05. Results: Of the total sample of 78 individuals who tested positive for COVID-19, the mean age was 84.6 years (SD=±7.8), 62 (79.5%) were female; 40 (51.3%) participants presented with COVID-19 symptoms. Living in a private NH (RR=3.6, 95% CI [1.2-11.0], p=0.023) and having suffered a stroke (RR=4.1, 95% CI [1.1-14.7], p=0.033) were positively associated with developing COVID-19 infection with symptoms. Conclusions: Having suffered a stroke and living permanently in a private NH were positively associated with symptomatic COVID-19 in this sample of institutionalized older people. Clinical Trials ID: NCT04297904
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-09-01T15:38:47Z
dc.date.available.fl_str_mv 2023-09-01T15:38:47Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv SOUZA, Dyego Leandro Bezerra de; ESCRIBÀ-SALVANS, Anna; RIEROLA-FOCHS, Sandra; FARRÉS-GODAYOL, Pau; MOLAS-TUNEU, Miriam; SKELTON, Dawn A.; GOUTAN-ROURA, Ester; MINOBES-MOLINA, Eduard; JEREZ-ROIG, Javier. Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesis-generating observational study. Journal Of Frailty, Sarcopenia And Falls, [S.L.], v. 8, n. 2, p. 74-82, 1 jun. 2023. Hylonome Publications. http://dx.doi.org/10.22540/jfsf-08-074. Disponível em: https://www.jfsf.eu/Article.php?AID=v08i02_074. Acesso em: 30 ago. 2023.
dc.identifier.uri.fl_str_mv https://repositorio.ufrn.br/handle/123456789/54655
dc.identifier.issn.none.fl_str_mv e2459-4148
dc.identifier.doi.none.fl_str_mv 10.22540/JFSF-08-074
identifier_str_mv SOUZA, Dyego Leandro Bezerra de; ESCRIBÀ-SALVANS, Anna; RIEROLA-FOCHS, Sandra; FARRÉS-GODAYOL, Pau; MOLAS-TUNEU, Miriam; SKELTON, Dawn A.; GOUTAN-ROURA, Ester; MINOBES-MOLINA, Eduard; JEREZ-ROIG, Javier. Risk factors for developing symptomatic COVID-19 in older residents of nursing homes: a hypothesis-generating observational study. Journal Of Frailty, Sarcopenia And Falls, [S.L.], v. 8, n. 2, p. 74-82, 1 jun. 2023. Hylonome Publications. http://dx.doi.org/10.22540/jfsf-08-074. Disponível em: https://www.jfsf.eu/Article.php?AID=v08i02_074. Acesso em: 30 ago. 2023.
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publisher.none.fl_str_mv Journal Of Frailty, Sarcopenia And Falls
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