Susceptibility vessel sign on T2* magnetic resonance imaging and recanalization results of mechanical thrombectomy with stent retrievers: a multicentre cohort study

• Autor(a) principal: Soize, S.
• Data de Publicação: 2015
• Outros Autores: Batista, André Lima, Regent, C. Rodriguez, Trystram, D., Tisserand, M., Turc, G., Serre, I., Hassen, W. Ben, Zuber, M., Calvet, D., Mas, J.-L., Meder, J.-F., Raymond, J., Pierot, L., Oppenheim, C., Naggara, O.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRN
• Texto Completo: https://repositorio.ufrn.br/handle/123456789/52480
• topic: ischaemic stroke; magnetic resonance imaging; thrombectomy; thrombus

Background and purpose: The susceptibility vessel sign (SVS) on T2*-weighted magnetic resonance imaging has been reported in several studies as a negative predictor of early recanalization after intravenous thrombolysis. The meaning of SVS regarding the results of mechanical thrombectomy with stent retrievers was investigated. Methods: Susceptibility vessel sign presence and length were studied in 153 acute ischaemic stroke patients (82 men; mean SD age 59 17 years, base line National Institutes of Health Stroke Scale score 17.2 6.5) from three stroke centres, treated with either mechanical thrombectomy alone (n = 84) or bridging therapy (n = 69). Variables were compared between recanalizers, defined as thrombolysis in cerebral infarction (TICI) scores ≥2b, and non-reca nalizers (TICI<2b). Results: The SVS was present in 113 (73.8%) patients. There was no associa tion between the presence of SVS and recanalization, obtained in 86 (56.2%) patients, in the whole population [odds ratio (OR) 1.24, 95% confidence inter val (CI) 0.53–2.92, P = 0.84) and in treatment subgroups (bridging: OR = 0.91, 95% CI 0.29–2.87, P = 1.0; thrombectomy alone: OR = 1.85, 95% CI 0.48–7.16, P = 0.54). However, in SVS+ patients, recanalization decreased with SVS length (OR 0.94 for each additional mm, 95% CI 0.89–0.99; P = 0.02). Conclusions: The success of recanalization in acute stroke patients treated with stent retrievers was related to thrombus length but not to the presence of SVS.