Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women

Detalhes bibliográficos
Autor(a) principal: Monteiro, Michelly Nóbrega
Data de Publicação: 2017
Outros Autores: Cobucci, Ricardo Ney Oliveira, Queiroz, Janice, Lucena, Eudes Euler de Souza, Vital, Ana Luísa Fernandes, Palitot, Tatyane Ribeiro de Castro, Eleutério Junior, José, Giraldo, Paulo César, Oliveira, Ana Katherine da Silveira Gonçalves de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRN
Texto Completo: https://repositorio.ufrn.br/handle/123456789/32067
Resumo: Introduction:Vaginal infections and modifications in the vaginal flora are very prevalent during pregnancy and have been associated with adverse obstetric outcomes, such as preterm labor, preterm premature rupture of membranes and low birth weight. Objective: To evaluate the prevalence and associations of bacterial vaginosis (BV) and pregnancy outcomes among Brazilian pregnant women in the third trimester. Methods:A prospective observational study was conducted assessing vaginal microbiota on bacterioscopy (wet mount and Gram stain), using vaginal swabs obtained from pregnant women between 26 and 32 weeks’ gestation. The women were monitored until delivery, and their pregnancy outcome and demographic data were collected using an interviewer-administered questionnaire. Results: BV was assessed using both Amsel’s criteria and Nugent’s score in 77 of 190 women, resulting in the prevalence of 42.5%. BV was significantly associated with preterm labor (risk ratio [RR], 2.89; 95% confidence interval [CI], 2.35–3.56) and low birth weight (RR, 2.17; 95%CI, 1.61–2.92). Premature rupture of membranes was not associated with BV. Conclusion: BV was found to be very frequent among Brazilian pregnant women in the third trimester and correlated to unfortunate pregnancy outcomes. Regular screening of pregnant women may allow for early treatment and prevention of some obstetric complications
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spelling Monteiro, Michelly NóbregaCobucci, Ricardo Ney OliveiraQueiroz, JaniceLucena, Eudes Euler de SouzaVital, Ana Luísa FernandesPalitot, Tatyane Ribeiro de CastroEleutério Junior, JoséGiraldo, Paulo CésarOliveira, Ana Katherine da Silveira Gonçalves de2021-04-07T11:34:52Z2021-04-07T11:34:52Z2017MONTEIRO, Michelly Nóbrega; COBUCCI, Ricardo Ney Oliveira; QUEIROZ, Janice; LUCENA, Eudes Euler de Souza; VITAL, Ana Luísa Fernandes; PALITOT, Tatyane Ribeiro de Castro; ELEUTÉRIO JUNIOR, José; GIRALDO, Paulo César; GONÇALVES, Ana Katherine. Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women. Jornal Brasileiro de Doencas Sexualmente Transmissiveis, [s. l.], v. 3, n. 29, p. 101-105, 2017. Disponível em: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-879137?lang=en. Acesso em: 21 jul. 2020.0103-4065 (print)2177-8264 (online)https://repositorio.ufrn.br/handle/123456789/32067Introduction:Vaginal infections and modifications in the vaginal flora are very prevalent during pregnancy and have been associated with adverse obstetric outcomes, such as preterm labor, preterm premature rupture of membranes and low birth weight. Objective: To evaluate the prevalence and associations of bacterial vaginosis (BV) and pregnancy outcomes among Brazilian pregnant women in the third trimester. Methods:A prospective observational study was conducted assessing vaginal microbiota on bacterioscopy (wet mount and Gram stain), using vaginal swabs obtained from pregnant women between 26 and 32 weeks’ gestation. The women were monitored until delivery, and their pregnancy outcome and demographic data were collected using an interviewer-administered questionnaire. Results: BV was assessed using both Amsel’s criteria and Nugent’s score in 77 of 190 women, resulting in the prevalence of 42.5%. BV was significantly associated with preterm labor (risk ratio [RR], 2.89; 95% confidence interval [CI], 2.35–3.56) and low birth weight (RR, 2.17; 95%CI, 1.61–2.92). Premature rupture of membranes was not associated with BV. Conclusion: BV was found to be very frequent among Brazilian pregnant women in the third trimester and correlated to unfortunate pregnancy outcomes. Regular screening of pregnant women may allow for early treatment and prevention of some obstetric complicationsIntrodução: Infecções vaginais e mudanças na flora vaginal são prevalentes durante a gravidez e têm sido associadas com desfechos obstétricos adversos, tais como trabalho de parto prematuro, amniorrexe prematura e baixo peso ao nascer. Objetivos: Correlacionar a presença de vaginose bacteriana (VB) com desfecho obstétrico desfavorável em mulheres brasileiras com gravidez no terceiro trimestre. Métodos: O estudo prospectivo observacional foi conduzido avaliando microbiota vaginal por bacterioscopia (a fresco e Gram) usando swab vaginal obtido de mulheres grávidas entre a 26 e a 32a semanas de gestação. As mulheres foram monitoradas até o parto, e os dados de seu seguimento e os demográficos foram coletados por meio de um questionário autoaplicável. Resultados: Foi diagnosticada VB, com base nos critérios de Amsel e de Nugent, em 77 mulheres entre as 190, demonstrando prevalência de 42.5%. VB foi significativamente associada com maior risco de parto prematuro (risk ratio [RR], 2.89; 95% intervalo de confiança [IC], 2.35–3.56) e de baixo peso ao nascer (RR, 2.17; 95%IC, 1.61–2.92). A rotura prematura das membranas não foi associada com VB. Conclusão: Foi constatada alta frequência de VB entre as mulheres brasileiras grávidas no terceiro trimestre, e a BV correlacionou-se com piores prognósticos da gravidez. O rastreio rotineiro de mulheres grávidas pode permitir um tratamento precoce e a prevenção de algumas complicações obstétricasUniversidade Federal FluminenseVaginosis, bacterialPregnancyPregnancy complicationsPremature birthInfant, low birth weightVaginose bacterianaGravidezComplicações na gravidezTrabalho de parto prematuroRecém-nascido de baixo pesoCorrelation between bacterial vaginosis and adverse obstetric outcomes in Brazilian womenCorrelação entre vaginose bacteriana e desfechos obstétricos desfavoráveis em mulheres brasileirasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNinfo:eu-repo/semantics/openAccessORIGINALVaginoseBacterianaDesfechos_Lucena_2017.pdfVaginoseBacterianaDesfechos_Lucena_2017.pdfapplication/pdf448020https://repositorio.ufrn.br/bitstream/123456789/32067/1/VaginoseBacterianaDesfechos_Lucena_2017.pdf7c4377185c3a201a03d0bfd7a767760dMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/32067/2/license.txte9597aa2854d128fd968be5edc8a28d9MD52TEXTVaginoseBacterianaDesfechos_Lucena_2017.pdf.txtVaginoseBacterianaDesfechos_Lucena_2017.pdf.txtExtracted texttext/plain26183https://repositorio.ufrn.br/bitstream/123456789/32067/3/VaginoseBacterianaDesfechos_Lucena_2017.pdf.txt74c60848654708b5b0684050a44b00faMD53THUMBNAILVaginoseBacterianaDesfechos_Lucena_2017.pdf.jpgVaginoseBacterianaDesfechos_Lucena_2017.pdf.jpgGenerated Thumbnailimage/jpeg1663https://repositorio.ufrn.br/bitstream/123456789/32067/4/VaginoseBacterianaDesfechos_Lucena_2017.pdf.jpge1f51e0b38cc917b87630dd32be7c2feMD54123456789/320672021-04-11 06:06:26.831oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-04-11T09:06:26Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.pt_BR.fl_str_mv Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women
dc.title.alternative.pt_BR.fl_str_mv Correlação entre vaginose bacteriana e desfechos obstétricos desfavoráveis em mulheres brasileiras
title Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women
spellingShingle Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women
Monteiro, Michelly Nóbrega
Vaginosis, bacterial
Pregnancy
Pregnancy complications
Premature birth
Infant, low birth weight
Vaginose bacteriana
Gravidez
Complicações na gravidez
Trabalho de parto prematuro
Recém-nascido de baixo peso
title_short Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women
title_full Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women
title_fullStr Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women
title_full_unstemmed Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women
title_sort Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women
author Monteiro, Michelly Nóbrega
author_facet Monteiro, Michelly Nóbrega
Cobucci, Ricardo Ney Oliveira
Queiroz, Janice
Lucena, Eudes Euler de Souza
Vital, Ana Luísa Fernandes
Palitot, Tatyane Ribeiro de Castro
Eleutério Junior, José
Giraldo, Paulo César
Oliveira, Ana Katherine da Silveira Gonçalves de
author_role author
author2 Cobucci, Ricardo Ney Oliveira
Queiroz, Janice
Lucena, Eudes Euler de Souza
Vital, Ana Luísa Fernandes
Palitot, Tatyane Ribeiro de Castro
Eleutério Junior, José
Giraldo, Paulo César
Oliveira, Ana Katherine da Silveira Gonçalves de
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Monteiro, Michelly Nóbrega
Cobucci, Ricardo Ney Oliveira
Queiroz, Janice
Lucena, Eudes Euler de Souza
Vital, Ana Luísa Fernandes
Palitot, Tatyane Ribeiro de Castro
Eleutério Junior, José
Giraldo, Paulo César
Oliveira, Ana Katherine da Silveira Gonçalves de
dc.subject.por.fl_str_mv Vaginosis, bacterial
Pregnancy
Pregnancy complications
Premature birth
Infant, low birth weight
Vaginose bacteriana
Gravidez
Complicações na gravidez
Trabalho de parto prematuro
Recém-nascido de baixo peso
topic Vaginosis, bacterial
Pregnancy
Pregnancy complications
Premature birth
Infant, low birth weight
Vaginose bacteriana
Gravidez
Complicações na gravidez
Trabalho de parto prematuro
Recém-nascido de baixo peso
description Introduction:Vaginal infections and modifications in the vaginal flora are very prevalent during pregnancy and have been associated with adverse obstetric outcomes, such as preterm labor, preterm premature rupture of membranes and low birth weight. Objective: To evaluate the prevalence and associations of bacterial vaginosis (BV) and pregnancy outcomes among Brazilian pregnant women in the third trimester. Methods:A prospective observational study was conducted assessing vaginal microbiota on bacterioscopy (wet mount and Gram stain), using vaginal swabs obtained from pregnant women between 26 and 32 weeks’ gestation. The women were monitored until delivery, and their pregnancy outcome and demographic data were collected using an interviewer-administered questionnaire. Results: BV was assessed using both Amsel’s criteria and Nugent’s score in 77 of 190 women, resulting in the prevalence of 42.5%. BV was significantly associated with preterm labor (risk ratio [RR], 2.89; 95% confidence interval [CI], 2.35–3.56) and low birth weight (RR, 2.17; 95%CI, 1.61–2.92). Premature rupture of membranes was not associated with BV. Conclusion: BV was found to be very frequent among Brazilian pregnant women in the third trimester and correlated to unfortunate pregnancy outcomes. Regular screening of pregnant women may allow for early treatment and prevention of some obstetric complications
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2021-04-07T11:34:52Z
dc.date.available.fl_str_mv 2021-04-07T11:34:52Z
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dc.identifier.citation.fl_str_mv MONTEIRO, Michelly Nóbrega; COBUCCI, Ricardo Ney Oliveira; QUEIROZ, Janice; LUCENA, Eudes Euler de Souza; VITAL, Ana Luísa Fernandes; PALITOT, Tatyane Ribeiro de Castro; ELEUTÉRIO JUNIOR, José; GIRALDO, Paulo César; GONÇALVES, Ana Katherine. Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women. Jornal Brasileiro de Doencas Sexualmente Transmissiveis, [s. l.], v. 3, n. 29, p. 101-105, 2017. Disponível em: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-879137?lang=en. Acesso em: 21 jul. 2020.
dc.identifier.uri.fl_str_mv https://repositorio.ufrn.br/handle/123456789/32067
dc.identifier.issn.none.fl_str_mv 0103-4065 (print)
2177-8264 (online)
identifier_str_mv MONTEIRO, Michelly Nóbrega; COBUCCI, Ricardo Ney Oliveira; QUEIROZ, Janice; LUCENA, Eudes Euler de Souza; VITAL, Ana Luísa Fernandes; PALITOT, Tatyane Ribeiro de Castro; ELEUTÉRIO JUNIOR, José; GIRALDO, Paulo César; GONÇALVES, Ana Katherine. Correlation between bacterial vaginosis and adverse obstetric outcomes in Brazilian women. Jornal Brasileiro de Doencas Sexualmente Transmissiveis, [s. l.], v. 3, n. 29, p. 101-105, 2017. Disponível em: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-879137?lang=en. Acesso em: 21 jul. 2020.
0103-4065 (print)
2177-8264 (online)
url https://repositorio.ufrn.br/handle/123456789/32067
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dc.publisher.none.fl_str_mv Universidade Federal Fluminense
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