Caracterização das oscilações gama e teta hipocampais na sincronização ao alimento em ratos wistar

• Autor(a) principal: Dias, Halan Dyego Batista
• Data de Publicação: 2016
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UFRN
• Texto Completo: https://repositorio.ufrn.br/handle/123456789/43254
• topic: Sincronização ao alimento; Food entrainment; Oscilador circadiano; Circadian oscillator; Hipocampo; Hippocampus; CNPQ::CIENCIAS BIOLOGICAS::FISIOLOGIA

Studies show that nocturnal rodents in a restricted feeding schedule exhibit food anticipatory activity (FAA). This behavior is modulated by a food entrained oscillator (FEO), which is proposed to be a network of interconnected brain structures. The hippocampus which shows genes and protein expression entrained to food availability is a candidate area to participate of this network. The aim of this study was to evaluate the participation of hippocampus on food entrainment as a possible structure belonging to network of oscillators which integrate the FEO. We used 5 male Wistar rats submitted to neuronal register of hippocampus in two experimental conditions: free available feeding and restricted feeding schedule. For each condition, the power of oscillations gamma and theta were calculated. Our results show an increase in hippocampus electric activity of gamma oscillations and a decrease of tetha oscillations three hours preceding food delivery in restricted feeding schedule rats. The gamma oscillations are related to process of facilitation of communication between cerebral areas. Therefore, the hippocampus can be a stronger candidate to participate of the network of interconnected brain structures that integrates the FEO.