Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/handle/123456789/55896 http://dx.doi.org/10.1016/j.clnesp.2021.12.018 |
Resumo: | Background & aims: Cancer influences body composition, including a loss of muscle mass (MM), associated with worse outcomes. The study aimed to evaluate the agreement between MM estimated by calf circumference (CC) and computed tomography (CT) image as a reference method. Methods: A cross-sectional study including patients (>20 years) diagnosed with cancer attending a reference center of oncology. Spearman's correlation was performed to verify the correlation between CC and MM by CT, including skeletal muscle area - SMA and skeletal muscle index - SMI. ROC curves, Kappa coefficient, sensitivity, specificity, positive and negative predictive values were obtained. Results: The study included 219 patients, age 62.9 ± 13.1 years (mean ± standard deviation). Low CC was observed in 43.8% of the patients, and 29.2% had low SMI. CC positively correlated with SMA (rho ¼ 0.333) and SMI (rho ¼ 0.329), and fair agreements (K ¼ 0.268) were observed between CC and SMI, with higher and significant values for males (K ¼ 0.332) and patients below 60 years (K ¼ 0.419). The area under the curve (AUC) for low CC to identifying low SMI was equal to 0.685 (CI 95% 0.606 e0.765). Low CC presented fair agreement to identify low SMI in the sample; however, the negative predictive value was almost 80% for all analyses. Conclusions: Low CC is not a surrogate for low SMI in patients with cancer, but it could be an alternative, non-invasive, easy-to-perform method to pre-screen patients with cancer with adequate SMI |
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Fayh, Ana Paula TrussardiSousa, Iasmin MatiasGonzalez, Maria CristinaBielemann, Renata MoraesRocha, Ilanna Marques GomesBarbalho, Erica RobertaCarvalho, Ana Lúcia MirandaMedeiros, Galtieri Otávio CunhaSilva, Flávia Moraes2023-12-13T22:15:04Z2023-12-13T22:15:04Z2022-02SOUSA, Iasmin Matias; GONZALEZ, Maria Cristina; BIELEMANN, Renata Moraes; ROCHA, Ilanna Marques Gomes; BARBALHO, Erica Roberta; CARVALHO, Ana Lúcia Miranda; MEDEIROS, Galtieri Otávio Cunha; SILVA, Flávia Moraes; FAYH, Ana Paula Trussardi. Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study. Clinical Nutrition Espen, [S.l.] v. 47, p. 183-188, fev. 2022. DOI: 10.1016/j.clnesp.2021.12.018. Disponível em: https://www.sciencedirect.com/science/article/pii/S2405457721011645?via%3Dihub. Acesso em: 12 dez. 2023.https://repositorio.ufrn.br/handle/123456789/55896http://dx.doi.org/10.1016/j.clnesp.2021.12.018Clinical Nutrition EspenNutritional statussolid tumoranthropometryskeletal muscle indexAgreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBackground & aims: Cancer influences body composition, including a loss of muscle mass (MM), associated with worse outcomes. The study aimed to evaluate the agreement between MM estimated by calf circumference (CC) and computed tomography (CT) image as a reference method. Methods: A cross-sectional study including patients (>20 years) diagnosed with cancer attending a reference center of oncology. Spearman's correlation was performed to verify the correlation between CC and MM by CT, including skeletal muscle area - SMA and skeletal muscle index - SMI. ROC curves, Kappa coefficient, sensitivity, specificity, positive and negative predictive values were obtained. Results: The study included 219 patients, age 62.9 ± 13.1 years (mean ± standard deviation). Low CC was observed in 43.8% of the patients, and 29.2% had low SMI. CC positively correlated with SMA (rho ¼ 0.333) and SMI (rho ¼ 0.329), and fair agreements (K ¼ 0.268) were observed between CC and SMI, with higher and significant values for males (K ¼ 0.332) and patients below 60 years (K ¼ 0.419). The area under the curve (AUC) for low CC to identifying low SMI was equal to 0.685 (CI 95% 0.606 e0.765). Low CC presented fair agreement to identify low SMI in the sample; however, the negative predictive value was almost 80% for all analyses. Conclusions: Low CC is not a surrogate for low SMI in patients with cancer, but it could be an alternative, non-invasive, easy-to-perform method to pre-screen patients with cancer with adequate SMIengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/55896/2/license.txte9597aa2854d128fd968be5edc8a28d9MD52123456789/558962023-12-13 19:15:16.862oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2023-12-13T22:15:16Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study |
title |
Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study |
spellingShingle |
Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study Fayh, Ana Paula Trussardi Nutritional status solid tumor anthropometry skeletal muscle index |
title_short |
Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study |
title_full |
Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study |
title_fullStr |
Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study |
title_full_unstemmed |
Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study |
title_sort |
Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study |
author |
Fayh, Ana Paula Trussardi |
author_facet |
Fayh, Ana Paula Trussardi Sousa, Iasmin Matias Gonzalez, Maria Cristina Bielemann, Renata Moraes Rocha, Ilanna Marques Gomes Barbalho, Erica Roberta Carvalho, Ana Lúcia Miranda Medeiros, Galtieri Otávio Cunha Silva, Flávia Moraes |
author_role |
author |
author2 |
Sousa, Iasmin Matias Gonzalez, Maria Cristina Bielemann, Renata Moraes Rocha, Ilanna Marques Gomes Barbalho, Erica Roberta Carvalho, Ana Lúcia Miranda Medeiros, Galtieri Otávio Cunha Silva, Flávia Moraes |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Fayh, Ana Paula Trussardi Sousa, Iasmin Matias Gonzalez, Maria Cristina Bielemann, Renata Moraes Rocha, Ilanna Marques Gomes Barbalho, Erica Roberta Carvalho, Ana Lúcia Miranda Medeiros, Galtieri Otávio Cunha Silva, Flávia Moraes |
dc.subject.por.fl_str_mv |
Nutritional status solid tumor anthropometry skeletal muscle index |
topic |
Nutritional status solid tumor anthropometry skeletal muscle index |
description |
Background & aims: Cancer influences body composition, including a loss of muscle mass (MM), associated with worse outcomes. The study aimed to evaluate the agreement between MM estimated by calf circumference (CC) and computed tomography (CT) image as a reference method. Methods: A cross-sectional study including patients (>20 years) diagnosed with cancer attending a reference center of oncology. Spearman's correlation was performed to verify the correlation between CC and MM by CT, including skeletal muscle area - SMA and skeletal muscle index - SMI. ROC curves, Kappa coefficient, sensitivity, specificity, positive and negative predictive values were obtained. Results: The study included 219 patients, age 62.9 ± 13.1 years (mean ± standard deviation). Low CC was observed in 43.8% of the patients, and 29.2% had low SMI. CC positively correlated with SMA (rho ¼ 0.333) and SMI (rho ¼ 0.329), and fair agreements (K ¼ 0.268) were observed between CC and SMI, with higher and significant values for males (K ¼ 0.332) and patients below 60 years (K ¼ 0.419). The area under the curve (AUC) for low CC to identifying low SMI was equal to 0.685 (CI 95% 0.606 e0.765). Low CC presented fair agreement to identify low SMI in the sample; however, the negative predictive value was almost 80% for all analyses. Conclusions: Low CC is not a surrogate for low SMI in patients with cancer, but it could be an alternative, non-invasive, easy-to-perform method to pre-screen patients with cancer with adequate SMI |
publishDate |
2022 |
dc.date.issued.fl_str_mv |
2022-02 |
dc.date.accessioned.fl_str_mv |
2023-12-13T22:15:04Z |
dc.date.available.fl_str_mv |
2023-12-13T22:15:04Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SOUSA, Iasmin Matias; GONZALEZ, Maria Cristina; BIELEMANN, Renata Moraes; ROCHA, Ilanna Marques Gomes; BARBALHO, Erica Roberta; CARVALHO, Ana Lúcia Miranda; MEDEIROS, Galtieri Otávio Cunha; SILVA, Flávia Moraes; FAYH, Ana Paula Trussardi. Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study. Clinical Nutrition Espen, [S.l.] v. 47, p. 183-188, fev. 2022. DOI: 10.1016/j.clnesp.2021.12.018. Disponível em: https://www.sciencedirect.com/science/article/pii/S2405457721011645?via%3Dihub. Acesso em: 12 dez. 2023. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/handle/123456789/55896 |
dc.identifier.doi.none.fl_str_mv |
http://dx.doi.org/10.1016/j.clnesp.2021.12.018 |
identifier_str_mv |
SOUSA, Iasmin Matias; GONZALEZ, Maria Cristina; BIELEMANN, Renata Moraes; ROCHA, Ilanna Marques Gomes; BARBALHO, Erica Roberta; CARVALHO, Ana Lúcia Miranda; MEDEIROS, Galtieri Otávio Cunha; SILVA, Flávia Moraes; FAYH, Ana Paula Trussardi. Agreement between muscle mass assessments by computed tomography and calf circumference in patients with cancer: a cross-sectional study. Clinical Nutrition Espen, [S.l.] v. 47, p. 183-188, fev. 2022. DOI: 10.1016/j.clnesp.2021.12.018. Disponível em: https://www.sciencedirect.com/science/article/pii/S2405457721011645?via%3Dihub. Acesso em: 12 dez. 2023. |
url |
https://repositorio.ufrn.br/handle/123456789/55896 http://dx.doi.org/10.1016/j.clnesp.2021.12.018 |
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eng |
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eng |
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Clinical Nutrition Espen |
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Clinical Nutrition Espen |
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