On the involvement of BDNF signaling in memory reconsolidation

Detalhes bibliográficos
Autor(a) principal: Gonzalez, Maria Carolina
Data de Publicação: 2019
Outros Autores: Radiske, Andressa, Cammarota, Martín Pablo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRN
Texto Completo: https://repositorio.ufrn.br/jspui/handle/123456789/27643
https://doi.org/10.3389/fncel.2019.00383
Resumo: When retrieval occurs concomitantly with novelty detection, mismatch perception or reactivation of conflicting information, consolidated memories can enter into a labile state, and to persist, must be restabilized through a protein synthesis-dependent reconsolidation process during which their strength and content can be modified. Extensive literature implicates brain-derived neurotrophic factor (BDNF), a key regulator of synaptogenesis and synaptic plasticity, in the acquisition, consolidation and extinction of several memory types. However, the participation of BDNF in memory reconsolidation has been less studied. In this review, we discuss recent reports supporting the involvement of BDNF signaling in reactivation-induced memory updating.
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spelling Gonzalez, Maria CarolinaRadiske, AndressaCammarota, Martín Pablo2019-09-05T13:48:08Z2019-09-05T13:48:08Z2019-08GONZALEZ, M. C.; RADISKE, A.; CAMMAROTA, M. On the involvement of BDNF signaling in memory reconsolidation. Front. Cell. Neurosci., [s. l.], v. 13, p. 383, ago. 2019. DOI: https://doi.org/10.3389/fncel.2019.00383. Disponível em: https://www.frontiersin.org/articles/10.3389/fncel.2019.00383/full. Acesso em: 05 set. 2019.https://repositorio.ufrn.br/jspui/handle/123456789/27643https://doi.org/10.3389/fncel.2019.00383Neurotrophinmemory reconsolidationTrkBBDNFretrievalOn the involvement of BDNF signaling in memory reconsolidationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleWhen retrieval occurs concomitantly with novelty detection, mismatch perception or reactivation of conflicting information, consolidated memories can enter into a labile state, and to persist, must be restabilized through a protein synthesis-dependent reconsolidation process during which their strength and content can be modified. Extensive literature implicates brain-derived neurotrophic factor (BDNF), a key regulator of synaptogenesis and synaptic plasticity, in the acquisition, consolidation and extinction of several memory types. However, the participation of BDNF in memory reconsolidation has been less studied. In this review, we discuss recent reports supporting the involvement of BDNF signaling in reactivation-induced memory updating.engreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNinfo:eu-repo/semantics/openAccessORIGINALMartinCammarota_ICe_2019_On the Involvement.pdfMartinCammarota_ICe_2019_On the Involvement.pdfMartinCammarota_ICe_2019_On the Involvementapplication/pdf533978https://repositorio.ufrn.br/bitstream/123456789/27643/1/MartinCammarota_ICe_2019_On%20the%20Involvement.pdfee21ab8b162ce3d9d08d6d5cb9b83d20MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/27643/2/license.txte9597aa2854d128fd968be5edc8a28d9MD52TEXTMartinCammarota_ICe_2019_On the Involvement.pdf.txtMartinCammarota_ICe_2019_On the Involvement.pdf.txtExtracted texttext/plain43955https://repositorio.ufrn.br/bitstream/123456789/27643/3/MartinCammarota_ICe_2019_On%20the%20Involvement.pdf.txtbcc3e0f3ba1c267bedfe8c18945a1439MD53THUMBNAILMartinCammarota_ICe_2019_On the Involvement.pdf.jpgMartinCammarota_ICe_2019_On the Involvement.pdf.jpgGenerated Thumbnailimage/jpeg1658https://repositorio.ufrn.br/bitstream/123456789/27643/4/MartinCammarota_ICe_2019_On%20the%20Involvement.pdf.jpgb548235a9174f2df7083d8d3efda406aMD54123456789/276432021-07-09 18:06:13.333oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-07-09T21:06:13Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.pt_BR.fl_str_mv On the involvement of BDNF signaling in memory reconsolidation
title On the involvement of BDNF signaling in memory reconsolidation
spellingShingle On the involvement of BDNF signaling in memory reconsolidation
Gonzalez, Maria Carolina
Neurotrophin
memory reconsolidation
TrkB
BDNF
retrieval
title_short On the involvement of BDNF signaling in memory reconsolidation
title_full On the involvement of BDNF signaling in memory reconsolidation
title_fullStr On the involvement of BDNF signaling in memory reconsolidation
title_full_unstemmed On the involvement of BDNF signaling in memory reconsolidation
title_sort On the involvement of BDNF signaling in memory reconsolidation
author Gonzalez, Maria Carolina
author_facet Gonzalez, Maria Carolina
Radiske, Andressa
Cammarota, Martín Pablo
author_role author
author2 Radiske, Andressa
Cammarota, Martín Pablo
author2_role author
author
dc.contributor.author.fl_str_mv Gonzalez, Maria Carolina
Radiske, Andressa
Cammarota, Martín Pablo
dc.subject.por.fl_str_mv Neurotrophin
memory reconsolidation
TrkB
BDNF
retrieval
topic Neurotrophin
memory reconsolidation
TrkB
BDNF
retrieval
description When retrieval occurs concomitantly with novelty detection, mismatch perception or reactivation of conflicting information, consolidated memories can enter into a labile state, and to persist, must be restabilized through a protein synthesis-dependent reconsolidation process during which their strength and content can be modified. Extensive literature implicates brain-derived neurotrophic factor (BDNF), a key regulator of synaptogenesis and synaptic plasticity, in the acquisition, consolidation and extinction of several memory types. However, the participation of BDNF in memory reconsolidation has been less studied. In this review, we discuss recent reports supporting the involvement of BDNF signaling in reactivation-induced memory updating.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-09-05T13:48:08Z
dc.date.available.fl_str_mv 2019-09-05T13:48:08Z
dc.date.issued.fl_str_mv 2019-08
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GONZALEZ, M. C.; RADISKE, A.; CAMMAROTA, M. On the involvement of BDNF signaling in memory reconsolidation. Front. Cell. Neurosci., [s. l.], v. 13, p. 383, ago. 2019. DOI: https://doi.org/10.3389/fncel.2019.00383. Disponível em: https://www.frontiersin.org/articles/10.3389/fncel.2019.00383/full. Acesso em: 05 set. 2019.
dc.identifier.uri.fl_str_mv https://repositorio.ufrn.br/jspui/handle/123456789/27643
dc.identifier.doi.none.fl_str_mv https://doi.org/10.3389/fncel.2019.00383
identifier_str_mv GONZALEZ, M. C.; RADISKE, A.; CAMMAROTA, M. On the involvement of BDNF signaling in memory reconsolidation. Front. Cell. Neurosci., [s. l.], v. 13, p. 383, ago. 2019. DOI: https://doi.org/10.3389/fncel.2019.00383. Disponível em: https://www.frontiersin.org/articles/10.3389/fncel.2019.00383/full. Acesso em: 05 set. 2019.
url https://repositorio.ufrn.br/jspui/handle/123456789/27643
https://doi.org/10.3389/fncel.2019.00383
dc.language.iso.fl_str_mv eng
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