Eosinofilia associada às Geohelmintoses: uma revisão literária

• Autor(a) principal: Marcelino, Brenna Marceliane de Melo
• Data de Publicação: 2017
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UFRN
• Texto Completo: https://repositorio.ufrn.br/handle/123456789/43160
• topic: Eosinofilia; Doenças Tropicais Negligenciadas; Helmintíase; Eosinophilia; Helminthiasis; Neglected Tropical Diseases; CNPQ::CIENCIAS BIOLOGICAS::PARASITOLOGIA::HELMINTOLOGIA DE PARASITOS::HELMINTOLOGIA HUMANA

The helminths are part of a call group of diseases: Neglected Tropical Diseases (NTDs) are a group of diseases that affect the poorest populations often living in atmosphere of remote regions hot and humid, with high levels of malnutrition, lack of clean water and low hygiene levels. Within the group of NTDs is the geohelminths comprising: Ascaris lumbricoides, Trichuris trichiura, Strongyloides stercoralis, and hookworms: Ancylostoma duodenale and Necator americanus. The helminth infections usually occur in children and young adults, which may cause reduction the nutritional status, growth retardation and low educational attainment beyond the emergence of iron deficiency anemia. Chronic helminth infections, such as those caused by geohelminths, exhibit a TH2 type immune response, where there is a superposition of regulatory mechanisms exerted on the basic pattern of the immune response. The humoral immune response to helminths is controlled by the IgE antibody. The allergenic immune response to intestinal parasites are variable and can be either acute or chronic. In parasitic infections, eosinophilia is usually constant and proportional to infection. Different degrees of eosinophilia may occur, depending on the etiologic agent, the level of infection, and the stage of the disease. The question of intestinal parasitosis in our country becomes even more pronounced, since there is no effective policy to control these parasites, such as: improvements in socioeconomic conditions, basic sanitation, and sanitary education. The administration of broad-spectrum anthelmintics as a form of treatment, such as Albendazole, reduces both the prevalence of the disease and the intensity of infection in the individual or the treated locality. Treatment of carriers is an effective form of control, since it reduces the circulation of worms in the environment and although they present low mortality rates, intestinal helminthiases still continue to represent a significant public health problem throughout the world.