Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/handle/123456789/54310 https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.034 |
Resumo: | Fluid-attenuated inversion recovery (FLAIR) vascular hyperintensities (FVHs) are common in patients with acute ischemic stroke, possibly representing impaired hemodynamics in the ischemic territory due to intracranial stenoocclusive disease. There are few reports on FVHs in patients with transient ischemic attack (TIA). Aims: We investigated the prevalence of FVHs and its clinical correlations in patients with TIA. Methods: We evaluated consecutive patients admitted with TIA from February 2009 to June 2012 who had undergone magnetic resonance imaging within 30 hours of symptoms onset and intracranial and extracranial vascular imaging. Two independent neuroradiologists determined the presence of FVHs. We assessed the relationship between FVHs, clinical presentation, vascular risk factors, neuroimaging characteristics, and the presence of large artery stenosis or occlusion. Results: Seventy-two patients with TIA were evaluated. FVHs were present in 12 (16.7%) patients. The overall agreement between examiners was good (κ = .67). There were no differences in the frequency of intracranial or cervical arterial stenosis in patients with and without FVH. In a multivariate logistic regression analysis including atrial fibrillation (AF), congestive heart failure, and diabetes, only AF remained in the final model. Conclusions: FVH signals on FLAIR images occur in patients with TIA and might correlate with clinical variables like AF and not only with large vessel occlusion. The presence of FVH in patients with TIA and AF might be a surrogate marker for a large vessel occlusion spontaneously recanalized or for impaired autoregulation in a previously ischemic vascular territory. |
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Figueiredo, Marcelo Marinho deAmaro Júnior, EdsonAlves, Maramélia Araújo de MirandaVazzoler, MarcelaMiranda, Renata Carolina Acre NunesSilva2023-07-31T19:53:28Z2023-07-31T19:53:28Z2017FIGUEIREDO, Marcelo Marinho de; AMARO JÚNIOR, Edson; ALVES, Maramélia Araújo de Miranda; VAZZOLER, Marcela; MIRANDA, Renata Carolina Acre Nunes; SILVA, Gisele Sampaio. Fluid-Attenuated Inversion Recovery Vascular Hyperintensities in Patients with Transient Ischemic Attack. Journal Of Stroke And Cerebrovascular Diseases, [S.L.], v. 26, n. 10, p. 2412-2415, out. 2017. Elsevier BV. http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.034. Disponível em: https://www.sciencedirect.com/science/article/pii/S1052305717302641. Acesso em: 25 jul. 2023.https://repositorio.ufrn.br/handle/123456789/54310https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.034Elseviertransient ischemic attackmagnetic resonance imagingfluid-attenuated inversion recoveryischemic strokeFluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attackinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFluid-attenuated inversion recovery (FLAIR) vascular hyperintensities (FVHs) are common in patients with acute ischemic stroke, possibly representing impaired hemodynamics in the ischemic territory due to intracranial stenoocclusive disease. There are few reports on FVHs in patients with transient ischemic attack (TIA). Aims: We investigated the prevalence of FVHs and its clinical correlations in patients with TIA. Methods: We evaluated consecutive patients admitted with TIA from February 2009 to June 2012 who had undergone magnetic resonance imaging within 30 hours of symptoms onset and intracranial and extracranial vascular imaging. Two independent neuroradiologists determined the presence of FVHs. We assessed the relationship between FVHs, clinical presentation, vascular risk factors, neuroimaging characteristics, and the presence of large artery stenosis or occlusion. Results: Seventy-two patients with TIA were evaluated. FVHs were present in 12 (16.7%) patients. The overall agreement between examiners was good (κ = .67). There were no differences in the frequency of intracranial or cervical arterial stenosis in patients with and without FVH. In a multivariate logistic regression analysis including atrial fibrillation (AF), congestive heart failure, and diabetes, only AF remained in the final model. Conclusions: FVH signals on FLAIR images occur in patients with TIA and might correlate with clinical variables like AF and not only with large vessel occlusion. The presence of FVH in patients with TIA and AF might be a surrogate marker for a large vessel occlusion spontaneously recanalized or for impaired autoregulation in a previously ischemic vascular territory.engreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/54310/2/license.txte9597aa2854d128fd968be5edc8a28d9MD52123456789/543102023-07-31 16:53:42.177oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2023-07-31T19:53:42Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack |
title |
Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack |
spellingShingle |
Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack Figueiredo, Marcelo Marinho de transient ischemic attack magnetic resonance imaging fluid-attenuated inversion recovery ischemic stroke |
title_short |
Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack |
title_full |
Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack |
title_fullStr |
Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack |
title_full_unstemmed |
Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack |
title_sort |
Fluid-attenuated inversion recovery vascular hyperintensities in patients with transient ischemic attack |
author |
Figueiredo, Marcelo Marinho de |
author_facet |
Figueiredo, Marcelo Marinho de Amaro Júnior, Edson Alves, Maramélia Araújo de Miranda Vazzoler, Marcela Miranda, Renata Carolina Acre Nunes Silva |
author_role |
author |
author2 |
Amaro Júnior, Edson Alves, Maramélia Araújo de Miranda Vazzoler, Marcela Miranda, Renata Carolina Acre Nunes Silva |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Figueiredo, Marcelo Marinho de Amaro Júnior, Edson Alves, Maramélia Araújo de Miranda Vazzoler, Marcela Miranda, Renata Carolina Acre Nunes Silva |
dc.subject.por.fl_str_mv |
transient ischemic attack magnetic resonance imaging fluid-attenuated inversion recovery ischemic stroke |
topic |
transient ischemic attack magnetic resonance imaging fluid-attenuated inversion recovery ischemic stroke |
description |
Fluid-attenuated inversion recovery (FLAIR) vascular hyperintensities (FVHs) are common in patients with acute ischemic stroke, possibly representing impaired hemodynamics in the ischemic territory due to intracranial stenoocclusive disease. There are few reports on FVHs in patients with transient ischemic attack (TIA). Aims: We investigated the prevalence of FVHs and its clinical correlations in patients with TIA. Methods: We evaluated consecutive patients admitted with TIA from February 2009 to June 2012 who had undergone magnetic resonance imaging within 30 hours of symptoms onset and intracranial and extracranial vascular imaging. Two independent neuroradiologists determined the presence of FVHs. We assessed the relationship between FVHs, clinical presentation, vascular risk factors, neuroimaging characteristics, and the presence of large artery stenosis or occlusion. Results: Seventy-two patients with TIA were evaluated. FVHs were present in 12 (16.7%) patients. The overall agreement between examiners was good (κ = .67). There were no differences in the frequency of intracranial or cervical arterial stenosis in patients with and without FVH. In a multivariate logistic regression analysis including atrial fibrillation (AF), congestive heart failure, and diabetes, only AF remained in the final model. Conclusions: FVH signals on FLAIR images occur in patients with TIA and might correlate with clinical variables like AF and not only with large vessel occlusion. The presence of FVH in patients with TIA and AF might be a surrogate marker for a large vessel occlusion spontaneously recanalized or for impaired autoregulation in a previously ischemic vascular territory. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2023-07-31T19:53:28Z |
dc.date.available.fl_str_mv |
2023-07-31T19:53:28Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
FIGUEIREDO, Marcelo Marinho de; AMARO JÚNIOR, Edson; ALVES, Maramélia Araújo de Miranda; VAZZOLER, Marcela; MIRANDA, Renata Carolina Acre Nunes; SILVA, Gisele Sampaio. Fluid-Attenuated Inversion Recovery Vascular Hyperintensities in Patients with Transient Ischemic Attack. Journal Of Stroke And Cerebrovascular Diseases, [S.L.], v. 26, n. 10, p. 2412-2415, out. 2017. Elsevier BV. http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.034. Disponível em: https://www.sciencedirect.com/science/article/pii/S1052305717302641. Acesso em: 25 jul. 2023. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/handle/123456789/54310 |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.034 |
identifier_str_mv |
FIGUEIREDO, Marcelo Marinho de; AMARO JÚNIOR, Edson; ALVES, Maramélia Araújo de Miranda; VAZZOLER, Marcela; MIRANDA, Renata Carolina Acre Nunes; SILVA, Gisele Sampaio. Fluid-Attenuated Inversion Recovery Vascular Hyperintensities in Patients with Transient Ischemic Attack. Journal Of Stroke And Cerebrovascular Diseases, [S.L.], v. 26, n. 10, p. 2412-2415, out. 2017. Elsevier BV. http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.034. Disponível em: https://www.sciencedirect.com/science/article/pii/S1052305717302641. Acesso em: 25 jul. 2023. |
url |
https://repositorio.ufrn.br/handle/123456789/54310 https://doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.034 |
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