Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings

Detalhes bibliográficos
Autor(a) principal: Moreira, Thaís de Almeida
Data de Publicação: 2017
Outros Autores: Lopes, Marcelo Coelho, Santos, Leilane Sousa, de Souza, Rafael Rocha, dos Reis, Júnior Artur, da Rocha Júnior, José Maurício, Bandarra, Márcio de Barros
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Medicina Veterinária (Recife. Online)
Texto Completo: https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794
Resumo: Leiomyosarcoma is a malignant neoplasm with origin in smooth muscles. It can originate in the vessel wall and interstitium of the spleen smooth muscle, which is considered rare. The objective of this study was to describe clinical and anatomopathological findings of a splenic leiomyosarcoma in an eight-year-old bitch of the Fila breed. This splenic leiomyosarcoma weighed 9.2 kg, and had 30×27×14 cm in dimension, rounded shape, irregular outline, reddish color alternating with pale areas, friable and hemorrhagic tissues, and necrotic center. After conventional histopathological examination, the suspected diagnosis (leiomyosarcoma) was confirmed by histochemical analysis using Masson's trichrome staining (which showed the reactivity of the muscle tissue) and by immunohistochemical analysis, showed positivity for smooth muscle actin, vimentin, and desmin. This study emphasizes the importance of associating histopathological evaluation with histochemical and immunohistochemical techniques for a diagnosis of this neoplasm. The occurrence of leiomyosarcoma reported here denotes the importance of considering it for a differential diagnosis in cases of splenic tumors.
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spelling Occurrence of splenic leiomyosarcoma in dog: anatomopathological findingscaninespleenneoplasmhistochemical.Leiomyosarcoma is a malignant neoplasm with origin in smooth muscles. It can originate in the vessel wall and interstitium of the spleen smooth muscle, which is considered rare. The objective of this study was to describe clinical and anatomopathological findings of a splenic leiomyosarcoma in an eight-year-old bitch of the Fila breed. This splenic leiomyosarcoma weighed 9.2 kg, and had 30×27×14 cm in dimension, rounded shape, irregular outline, reddish color alternating with pale areas, friable and hemorrhagic tissues, and necrotic center. After conventional histopathological examination, the suspected diagnosis (leiomyosarcoma) was confirmed by histochemical analysis using Masson's trichrome staining (which showed the reactivity of the muscle tissue) and by immunohistochemical analysis, showed positivity for smooth muscle actin, vimentin, and desmin. This study emphasizes the importance of associating histopathological evaluation with histochemical and immunohistochemical techniques for a diagnosis of this neoplasm. The occurrence of leiomyosarcoma reported here denotes the importance of considering it for a differential diagnosis in cases of splenic tumors.MEDICINA VETERINÁRIA2017-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/179410.26605/medvet-n3-1794Medicina Veterinária; v. 11 n. 3 (2017); 197-2022675-66171809-4678reponame:Medicina Veterinária (Recife. Online)instname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEporenghttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794/1602https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794/1603Copyright (c) 2017 Medicina Veterinária (UFRPE)info:eu-repo/semantics/openAccessMoreira, Thaís de AlmeidaLopes, Marcelo CoelhoSantos, Leilane Sousade Souza, Rafael Rochados Reis, Júnior Arturda Rocha Júnior, José MaurícioBandarra, Márcio de Barros2018-01-16T10:52:24Zoai:ojs.10.0.7.8:article/1794Revistahttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/PUBhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/oairevmedvet@ufrpe.br1809-46782675-6617opendoar:2018-01-16T10:52:24Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)false
dc.title.none.fl_str_mv Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
title Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
spellingShingle Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
Moreira, Thaís de Almeida
canine
spleen
neoplasm
histochemical.
title_short Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
title_full Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
title_fullStr Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
title_full_unstemmed Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
title_sort Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
author Moreira, Thaís de Almeida
author_facet Moreira, Thaís de Almeida
Lopes, Marcelo Coelho
Santos, Leilane Sousa
de Souza, Rafael Rocha
dos Reis, Júnior Artur
da Rocha Júnior, José Maurício
Bandarra, Márcio de Barros
author_role author
author2 Lopes, Marcelo Coelho
Santos, Leilane Sousa
de Souza, Rafael Rocha
dos Reis, Júnior Artur
da Rocha Júnior, José Maurício
Bandarra, Márcio de Barros
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Moreira, Thaís de Almeida
Lopes, Marcelo Coelho
Santos, Leilane Sousa
de Souza, Rafael Rocha
dos Reis, Júnior Artur
da Rocha Júnior, José Maurício
Bandarra, Márcio de Barros
dc.subject.por.fl_str_mv canine
spleen
neoplasm
histochemical.
topic canine
spleen
neoplasm
histochemical.
description Leiomyosarcoma is a malignant neoplasm with origin in smooth muscles. It can originate in the vessel wall and interstitium of the spleen smooth muscle, which is considered rare. The objective of this study was to describe clinical and anatomopathological findings of a splenic leiomyosarcoma in an eight-year-old bitch of the Fila breed. This splenic leiomyosarcoma weighed 9.2 kg, and had 30×27×14 cm in dimension, rounded shape, irregular outline, reddish color alternating with pale areas, friable and hemorrhagic tissues, and necrotic center. After conventional histopathological examination, the suspected diagnosis (leiomyosarcoma) was confirmed by histochemical analysis using Masson's trichrome staining (which showed the reactivity of the muscle tissue) and by immunohistochemical analysis, showed positivity for smooth muscle actin, vimentin, and desmin. This study emphasizes the importance of associating histopathological evaluation with histochemical and immunohistochemical techniques for a diagnosis of this neoplasm. The occurrence of leiomyosarcoma reported here denotes the importance of considering it for a differential diagnosis in cases of splenic tumors.
publishDate 2017
dc.date.none.fl_str_mv 2017-12-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794
10.26605/medvet-n3-1794
url https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794
identifier_str_mv 10.26605/medvet-n3-1794
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794/1602
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794/1603
dc.rights.driver.fl_str_mv Copyright (c) 2017 Medicina Veterinária (UFRPE)
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Medicina Veterinária (UFRPE)
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MEDICINA VETERINÁRIA
publisher.none.fl_str_mv MEDICINA VETERINÁRIA
dc.source.none.fl_str_mv Medicina Veterinária; v. 11 n. 3 (2017); 197-202
2675-6617
1809-4678
reponame:Medicina Veterinária (Recife. Online)
instname:Universidade Federal Rural de Pernambuco (UFRPE)
instacron:UFRPE
instname_str Universidade Federal Rural de Pernambuco (UFRPE)
instacron_str UFRPE
institution UFRPE
reponame_str Medicina Veterinária (Recife. Online)
collection Medicina Veterinária (Recife. Online)
repository.name.fl_str_mv Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)
repository.mail.fl_str_mv revmedvet@ufrpe.br
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