Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Medicina Veterinária (Recife. Online) |
Texto Completo: | https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794 |
Resumo: | Leiomyosarcoma is a malignant neoplasm with origin in smooth muscles. It can originate in the vessel wall and interstitium of the spleen smooth muscle, which is considered rare. The objective of this study was to describe clinical and anatomopathological findings of a splenic leiomyosarcoma in an eight-year-old bitch of the Fila breed. This splenic leiomyosarcoma weighed 9.2 kg, and had 30×27×14 cm in dimension, rounded shape, irregular outline, reddish color alternating with pale areas, friable and hemorrhagic tissues, and necrotic center. After conventional histopathological examination, the suspected diagnosis (leiomyosarcoma) was confirmed by histochemical analysis using Masson's trichrome staining (which showed the reactivity of the muscle tissue) and by immunohistochemical analysis, showed positivity for smooth muscle actin, vimentin, and desmin. This study emphasizes the importance of associating histopathological evaluation with histochemical and immunohistochemical techniques for a diagnosis of this neoplasm. The occurrence of leiomyosarcoma reported here denotes the importance of considering it for a differential diagnosis in cases of splenic tumors. |
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Medicina Veterinária (Recife. Online) |
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Occurrence of splenic leiomyosarcoma in dog: anatomopathological findingscaninespleenneoplasmhistochemical.Leiomyosarcoma is a malignant neoplasm with origin in smooth muscles. It can originate in the vessel wall and interstitium of the spleen smooth muscle, which is considered rare. The objective of this study was to describe clinical and anatomopathological findings of a splenic leiomyosarcoma in an eight-year-old bitch of the Fila breed. This splenic leiomyosarcoma weighed 9.2 kg, and had 30×27×14 cm in dimension, rounded shape, irregular outline, reddish color alternating with pale areas, friable and hemorrhagic tissues, and necrotic center. After conventional histopathological examination, the suspected diagnosis (leiomyosarcoma) was confirmed by histochemical analysis using Masson's trichrome staining (which showed the reactivity of the muscle tissue) and by immunohistochemical analysis, showed positivity for smooth muscle actin, vimentin, and desmin. This study emphasizes the importance of associating histopathological evaluation with histochemical and immunohistochemical techniques for a diagnosis of this neoplasm. The occurrence of leiomyosarcoma reported here denotes the importance of considering it for a differential diagnosis in cases of splenic tumors.MEDICINA VETERINÁRIA2017-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/179410.26605/medvet-n3-1794Medicina Veterinária; v. 11 n. 3 (2017); 197-2022675-66171809-4678reponame:Medicina Veterinária (Recife. Online)instname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEporenghttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794/1602https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794/1603Copyright (c) 2017 Medicina Veterinária (UFRPE)info:eu-repo/semantics/openAccessMoreira, Thaís de AlmeidaLopes, Marcelo CoelhoSantos, Leilane Sousade Souza, Rafael Rochados Reis, Júnior Arturda Rocha Júnior, José MaurícioBandarra, Márcio de Barros2018-01-16T10:52:24Zoai:ojs.10.0.7.8:article/1794Revistahttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/PUBhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/oairevmedvet@ufrpe.br1809-46782675-6617opendoar:2018-01-16T10:52:24Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)false |
dc.title.none.fl_str_mv |
Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings |
title |
Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings |
spellingShingle |
Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings Moreira, Thaís de Almeida canine spleen neoplasm histochemical. |
title_short |
Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings |
title_full |
Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings |
title_fullStr |
Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings |
title_full_unstemmed |
Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings |
title_sort |
Occurrence of splenic leiomyosarcoma in dog: anatomopathological findings |
author |
Moreira, Thaís de Almeida |
author_facet |
Moreira, Thaís de Almeida Lopes, Marcelo Coelho Santos, Leilane Sousa de Souza, Rafael Rocha dos Reis, Júnior Artur da Rocha Júnior, José Maurício Bandarra, Márcio de Barros |
author_role |
author |
author2 |
Lopes, Marcelo Coelho Santos, Leilane Sousa de Souza, Rafael Rocha dos Reis, Júnior Artur da Rocha Júnior, José Maurício Bandarra, Márcio de Barros |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Moreira, Thaís de Almeida Lopes, Marcelo Coelho Santos, Leilane Sousa de Souza, Rafael Rocha dos Reis, Júnior Artur da Rocha Júnior, José Maurício Bandarra, Márcio de Barros |
dc.subject.por.fl_str_mv |
canine spleen neoplasm histochemical. |
topic |
canine spleen neoplasm histochemical. |
description |
Leiomyosarcoma is a malignant neoplasm with origin in smooth muscles. It can originate in the vessel wall and interstitium of the spleen smooth muscle, which is considered rare. The objective of this study was to describe clinical and anatomopathological findings of a splenic leiomyosarcoma in an eight-year-old bitch of the Fila breed. This splenic leiomyosarcoma weighed 9.2 kg, and had 30×27×14 cm in dimension, rounded shape, irregular outline, reddish color alternating with pale areas, friable and hemorrhagic tissues, and necrotic center. After conventional histopathological examination, the suspected diagnosis (leiomyosarcoma) was confirmed by histochemical analysis using Masson's trichrome staining (which showed the reactivity of the muscle tissue) and by immunohistochemical analysis, showed positivity for smooth muscle actin, vimentin, and desmin. This study emphasizes the importance of associating histopathological evaluation with histochemical and immunohistochemical techniques for a diagnosis of this neoplasm. The occurrence of leiomyosarcoma reported here denotes the importance of considering it for a differential diagnosis in cases of splenic tumors. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-12-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794 10.26605/medvet-n3-1794 |
url |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794 |
identifier_str_mv |
10.26605/medvet-n3-1794 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794/1602 https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/1794/1603 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Medicina Veterinária (UFRPE) info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Medicina Veterinária (UFRPE) |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
MEDICINA VETERINÁRIA |
publisher.none.fl_str_mv |
MEDICINA VETERINÁRIA |
dc.source.none.fl_str_mv |
Medicina Veterinária; v. 11 n. 3 (2017); 197-202 2675-6617 1809-4678 reponame:Medicina Veterinária (Recife. Online) instname:Universidade Federal Rural de Pernambuco (UFRPE) instacron:UFRPE |
instname_str |
Universidade Federal Rural de Pernambuco (UFRPE) |
instacron_str |
UFRPE |
institution |
UFRPE |
reponame_str |
Medicina Veterinária (Recife. Online) |
collection |
Medicina Veterinária (Recife. Online) |
repository.name.fl_str_mv |
Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE) |
repository.mail.fl_str_mv |
revmedvet@ufrpe.br |
_version_ |
1806552250938556416 |