Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica

Detalhes bibliográficos
Autor(a) principal: Machado, Tao
Data de Publicação: 2014
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFRR
Texto Completo: http://repositorio.ufrr.br:8080/jspui/handle/prefix/714
Resumo: Tuberculosis is among the ten main causes of death in the world and Brazil is one of 22 countries that account for 80 % of the global burden of disease. Pleural presentation, the main object of this study, is the most common extrapulmonary TB form in HIV-seronegative individuals and always appears as a differential diagnosis to be considered in patients with pleural effusions. The main objective was to know the quality of diagnoses and the epidemiological profile of patients with pleural tuberculosis in the state of Roraima aiming to offer a technical foundation to public policies destined to fight the disease. The diagnosis of pleural tuberculosis is based primarily on the identification of Mycobacterium tuberculosis on direct examination or culture of pleural fluid or pleural tissue fragment, as well as in the presence of granuloma on histopathological analysis of the tissue sample. The present study was designed as a qualitative and quantitative transversal research to evaluate the diagnostic criteria being used and the determinants of pleural disease presentation in the state of Roraima, located in northern Brazil, within the limits of the Amazon, and with extensive socio-cultural and environmental diversity. This is an observational, retrospective and descriptive study based on a review of secondary SINAN data, including all cases of pleural tuberculosis reported from 2005 to 2013. Of 1.395 reported cases of tuberculosis in the period, 8.3% were of pleural presentation, totaling 38.9% of extrapulmonary cases in the sample. The incidence rate of this presentation did not follow the downward trend of pulmonary tuberculosis in the period. The prevalence of quality diagnosis was found to be 28.5 % (95% CI: 20.4 to 37.6 %), and in a univariate analysis, no variable among the possible clinical and demographic characteristics searched in the data basis had significant impact in the quality of the diagnosis. The main conclusion of the study indicates the need for a specific referral policy at a state level in order to facilitate access to diagnostic methods recommended by the National Tuberculosis Control Programme available in the health system.
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spelling Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnósticaPleural tuberculosis in the State of Roraima during 2005-2013 : epidemiological profile and quality of diagnosisTuberculoseTuberculose pleuralDiagnósticoRoraimaTuberculosisPleural tuberculosisDiagnosisCNPQ::CIENCIAS DA SAUDETuberculosis is among the ten main causes of death in the world and Brazil is one of 22 countries that account for 80 % of the global burden of disease. Pleural presentation, the main object of this study, is the most common extrapulmonary TB form in HIV-seronegative individuals and always appears as a differential diagnosis to be considered in patients with pleural effusions. The main objective was to know the quality of diagnoses and the epidemiological profile of patients with pleural tuberculosis in the state of Roraima aiming to offer a technical foundation to public policies destined to fight the disease. The diagnosis of pleural tuberculosis is based primarily on the identification of Mycobacterium tuberculosis on direct examination or culture of pleural fluid or pleural tissue fragment, as well as in the presence of granuloma on histopathological analysis of the tissue sample. The present study was designed as a qualitative and quantitative transversal research to evaluate the diagnostic criteria being used and the determinants of pleural disease presentation in the state of Roraima, located in northern Brazil, within the limits of the Amazon, and with extensive socio-cultural and environmental diversity. This is an observational, retrospective and descriptive study based on a review of secondary SINAN data, including all cases of pleural tuberculosis reported from 2005 to 2013. Of 1.395 reported cases of tuberculosis in the period, 8.3% were of pleural presentation, totaling 38.9% of extrapulmonary cases in the sample. The incidence rate of this presentation did not follow the downward trend of pulmonary tuberculosis in the period. The prevalence of quality diagnosis was found to be 28.5 % (95% CI: 20.4 to 37.6 %), and in a univariate analysis, no variable among the possible clinical and demographic characteristics searched in the data basis had significant impact in the quality of the diagnosis. The main conclusion of the study indicates the need for a specific referral policy at a state level in order to facilitate access to diagnostic methods recommended by the National Tuberculosis Control Programme available in the health system.A tuberculose está entre as dez principais causas de morte no mundo e o Brasil é um dos 22 países que concentram 80% da carga mundial da doença. A apresentação pleural, objeto central do presente estudo, é a mais comum forma extrapulmonar em indivíduos HIV soronegativos e sempre aparece como diagnóstico diferencial a ser considerado nos portadores de derrames pleurais no País. O diagnóstico de tuberculose pleural fundamenta-se principalmente na identificação do agente Mycobacterium tuberculosis no exame direto ou cultura do líquido pleural ou dos fragmentos de tecido pleural, assim como na presença de granuloma na análise histopatológica dos mesmos. O objetivo principal deste trabalho é conhecer a qualidade dos diagnósticos e o perfil epidemiológico dos portadores de tuberculose pleural no estado de Roraima visando embasar tecnicamente o fomento e aplicação de políticas públicas para o enfrentamento da doença em questão. O presente estudo foi desenhado como uma pesquisa quali-quantitativa do tipo corte transversal para avaliar os critérios diagnósticos utilizados e seus determinantes da apresentação pleural da doença no estado de Roraima, localizado na Região Norte do Brasil, dentro dos limites da Amazônia Legal, local que possui extensa diversidade sociocultural e ambiental. Trata-se de um estudo observacional, retrospectivo e descritivo baseado na revisão de dados secundários do SINAN, incluindo todos os casos notificados como portadores de tuberculose pleural de 2005 a 2013 no referido Estado. Dos 1.395 casos de tuberculose notificados no período, 8,3% foram da apresentação pleural, totalizando 38,9% das formas extrapulmonares na amostra. A taxa de incidência desta apresentação não acompanhou a tendência decrescente da forma pulmonar da doença no período. A prevalência de diagnósticos de qualidade encontrada foi de 28,5% (IC95%: 20,4 a 37,6%), e, em análise univariada nenhuma variável explicativa dentre as características demográficas e clínicas possíveis de serem apuradas no banco de dados tiveram impacto significativo na qualidade dos diagnósticos. A principal conclusão do estudo remete à necessidade de uma política de referenciamento específica a nível estadual no intuito de facilitar o acesso aos métodos diagnósticos preconizados pelo Programa Nacional de Controle da Tuberculose disponíveis no sistema de saúde.Agência 1Universidade Federal de RoraimaBrasilPRPPG - Pró-reitoria de Pesquisa e Pós-GraduaçãoPROCISA - Programa de Pós-Graduação em Ciências da SaúdeUFRRBuenafuente, Sandra Maria Francohttp://lattes.cnpq.br/7018219463846256Fonseca, Allex Jardim dahttp://lattes.cnpq.br/0260920834375160Machado, Tao2022-04-12T16:48:39Z20222022-04-12T16:48:39Z2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisMACHADO, Tao. Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica. 2014. 85f. Dissertação (Mestrado em Ciências da Saúde) - Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Roraima, Boa Vista, 2014.http://repositorio.ufrr.br:8080/jspui/handle/prefix/714porAttribution-NonCommercial-ShareAlike 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-sa/3.0/br/info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRRinstname:Universidade Federal de Roraima (UFRR)instacron:UFRR2024-02-26T15:46:29Zoai:repositorio.ufrr.br:prefix/714Repositório InstitucionalPUBhttp://repositorio.ufrr.br:8080/oai/requestangelsenhora@gmail.comopendoar:2024-02-26T15:46:29Repositório Institucional da UFRR - Universidade Federal de Roraima (UFRR)false
dc.title.none.fl_str_mv Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica
Pleural tuberculosis in the State of Roraima during 2005-2013 : epidemiological profile and quality of diagnosis
title Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica
spellingShingle Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica
Machado, Tao
Tuberculose
Tuberculose pleural
Diagnóstico
Roraima
Tuberculosis
Pleural tuberculosis
Diagnosis
CNPQ::CIENCIAS DA SAUDE
title_short Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica
title_full Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica
title_fullStr Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica
title_full_unstemmed Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica
title_sort Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica
author Machado, Tao
author_facet Machado, Tao
author_role author
dc.contributor.none.fl_str_mv Buenafuente, Sandra Maria Franco
http://lattes.cnpq.br/7018219463846256
Fonseca, Allex Jardim da
http://lattes.cnpq.br/0260920834375160
dc.contributor.author.fl_str_mv Machado, Tao
dc.subject.por.fl_str_mv Tuberculose
Tuberculose pleural
Diagnóstico
Roraima
Tuberculosis
Pleural tuberculosis
Diagnosis
CNPQ::CIENCIAS DA SAUDE
topic Tuberculose
Tuberculose pleural
Diagnóstico
Roraima
Tuberculosis
Pleural tuberculosis
Diagnosis
CNPQ::CIENCIAS DA SAUDE
description Tuberculosis is among the ten main causes of death in the world and Brazil is one of 22 countries that account for 80 % of the global burden of disease. Pleural presentation, the main object of this study, is the most common extrapulmonary TB form in HIV-seronegative individuals and always appears as a differential diagnosis to be considered in patients with pleural effusions. The main objective was to know the quality of diagnoses and the epidemiological profile of patients with pleural tuberculosis in the state of Roraima aiming to offer a technical foundation to public policies destined to fight the disease. The diagnosis of pleural tuberculosis is based primarily on the identification of Mycobacterium tuberculosis on direct examination or culture of pleural fluid or pleural tissue fragment, as well as in the presence of granuloma on histopathological analysis of the tissue sample. The present study was designed as a qualitative and quantitative transversal research to evaluate the diagnostic criteria being used and the determinants of pleural disease presentation in the state of Roraima, located in northern Brazil, within the limits of the Amazon, and with extensive socio-cultural and environmental diversity. This is an observational, retrospective and descriptive study based on a review of secondary SINAN data, including all cases of pleural tuberculosis reported from 2005 to 2013. Of 1.395 reported cases of tuberculosis in the period, 8.3% were of pleural presentation, totaling 38.9% of extrapulmonary cases in the sample. The incidence rate of this presentation did not follow the downward trend of pulmonary tuberculosis in the period. The prevalence of quality diagnosis was found to be 28.5 % (95% CI: 20.4 to 37.6 %), and in a univariate analysis, no variable among the possible clinical and demographic characteristics searched in the data basis had significant impact in the quality of the diagnosis. The main conclusion of the study indicates the need for a specific referral policy at a state level in order to facilitate access to diagnostic methods recommended by the National Tuberculosis Control Programme available in the health system.
publishDate 2014
dc.date.none.fl_str_mv 2014
2022-04-12T16:48:39Z
2022
2022-04-12T16:48:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv MACHADO, Tao. Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica. 2014. 85f. Dissertação (Mestrado em Ciências da Saúde) - Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Roraima, Boa Vista, 2014.
http://repositorio.ufrr.br:8080/jspui/handle/prefix/714
identifier_str_mv MACHADO, Tao. Tuberculose pleural no Estado de Roraima no período de 2005-2013: perfil epidemiológico e qualidade diagnóstica. 2014. 85f. Dissertação (Mestrado em Ciências da Saúde) - Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Roraima, Boa Vista, 2014.
url http://repositorio.ufrr.br:8080/jspui/handle/prefix/714
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv Attribution-NonCommercial-ShareAlike 3.0 Brazil
http://creativecommons.org/licenses/by-nc-sa/3.0/br/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-ShareAlike 3.0 Brazil
http://creativecommons.org/licenses/by-nc-sa/3.0/br/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Roraima
Brasil
PRPPG - Pró-reitoria de Pesquisa e Pós-Graduação
PROCISA - Programa de Pós-Graduação em Ciências da Saúde
UFRR
publisher.none.fl_str_mv Universidade Federal de Roraima
Brasil
PRPPG - Pró-reitoria de Pesquisa e Pós-Graduação
PROCISA - Programa de Pós-Graduação em Ciências da Saúde
UFRR
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRR
instname:Universidade Federal de Roraima (UFRR)
instacron:UFRR
instname_str Universidade Federal de Roraima (UFRR)
instacron_str UFRR
institution UFRR
reponame_str Repositório Institucional da UFRR
collection Repositório Institucional da UFRR
repository.name.fl_str_mv Repositório Institucional da UFRR - Universidade Federal de Roraima (UFRR)
repository.mail.fl_str_mv angelsenhora@gmail.com
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