Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares
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| Data de Publicação: | 2011 |
| Tipo de documento: | Tese |
| Idioma: | por |
| Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFRRJ |
| Texto Completo: | https://rima.ufrrj.br/jspui/handle/20.500.14407/9180 |
Resumo: | Este trabalho visou estudar o pâncreas endócrino de morcegos com diferentes hábitos alimentares (hematófago D. ecaudata, nectarívoro A. geoffroyi e insetívoro P. personatus), através de análise histológica, morfométrica e estereológica. Foram utilizados ao todo seis animais de cada grupo, coletados na caverna casa de Pedra (Sergipe). O pâncreas foi processado através das técnicas histológicas de rotina para inclusão em parafina. Histologicamente, foram identificado os componentes exócrinos (ácinos secretores e seus ductos associados) e endócrinos (ilhotas pancreáticas) do pâncreas. Foram observadas células imunoreativas (IR) à insulina, glucagon e somatostatina espalhadas isoladamente no pâncreas exócrino e, na região de tecido conjuntivo próximo aos ductos pancreáticos, foram identificadas células IR à insulina, glucagon e somatostatina. Células com a presença de processos citoplasmáticos foram visualizadas nas ilhotas. A massa de tecido pancreático total sobre a massa corporal não ultrapassa a relação de 0,6%, sendo esta relação maior nos morcegos insetívoros (0,6%) e menor nos morcegos nectarívoros (0,3%). O diâmetro das ilhotas variou entre as espécies sendo de 88,16 μm no morcego nectarívoro, de 56,94 μm no morcego hematófago e de 40,47 μm no morcego insetívoro. A análise estereológica mostrou uma densidade de volume (Vv) do pâncreas endócrino de 3,4% no morcego insetívoro, 6,1% no morcego nectarívoro e de 4,1% no morcego hematófago. A massa das ilhotas foi de 0,15 no morcego insetívoro, 0,24 no morcego nectarívoro e 0,48 no morcego hematófago. A densidade de volume das células α foi de (25,8%, 14,7, 16,2%), células β (35,5%, 8,7%, 54,8%) e células δ (3,9%, 6,2%, 14,3%) nos morcegos P. personatus, A. geoffroyi e D. ecaudata, respectivamente. As diferenças observadas entre espécies nos diversos parâmetros analisados podem refletir diferenças inter-específicas, assim como adaptações morfológicas das espécies ao seus hábitos alimentares |
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Santos, Clarice Machado dosSales, Armando164050567-91http://lattes.cnpq.br/7306314893432986Pinheiro, Nadja LimaSilva, Simone Florim daGitirana, Lycia de BritoMendes, Rosa Maria Marcos086140217-04http://lattes.cnpq.br/65084252012019852023-12-21T18:35:58Z2023-12-21T18:35:58Z2011-05-04SANTOS, Clarice Machado dos. Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares. 2011. 44 f. Tese (Doutorado em Biologia Animal) - Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica - RJ, 2011.https://rima.ufrrj.br/jspui/handle/20.500.14407/9180Este trabalho visou estudar o pâncreas endócrino de morcegos com diferentes hábitos alimentares (hematófago D. ecaudata, nectarívoro A. geoffroyi e insetívoro P. personatus), através de análise histológica, morfométrica e estereológica. Foram utilizados ao todo seis animais de cada grupo, coletados na caverna casa de Pedra (Sergipe). O pâncreas foi processado através das técnicas histológicas de rotina para inclusão em parafina. Histologicamente, foram identificado os componentes exócrinos (ácinos secretores e seus ductos associados) e endócrinos (ilhotas pancreáticas) do pâncreas. Foram observadas células imunoreativas (IR) à insulina, glucagon e somatostatina espalhadas isoladamente no pâncreas exócrino e, na região de tecido conjuntivo próximo aos ductos pancreáticos, foram identificadas células IR à insulina, glucagon e somatostatina. Células com a presença de processos citoplasmáticos foram visualizadas nas ilhotas. A massa de tecido pancreático total sobre a massa corporal não ultrapassa a relação de 0,6%, sendo esta relação maior nos morcegos insetívoros (0,6%) e menor nos morcegos nectarívoros (0,3%). O diâmetro das ilhotas variou entre as espécies sendo de 88,16 μm no morcego nectarívoro, de 56,94 μm no morcego hematófago e de 40,47 μm no morcego insetívoro. A análise estereológica mostrou uma densidade de volume (Vv) do pâncreas endócrino de 3,4% no morcego insetívoro, 6,1% no morcego nectarívoro e de 4,1% no morcego hematófago. A massa das ilhotas foi de 0,15 no morcego insetívoro, 0,24 no morcego nectarívoro e 0,48 no morcego hematófago. A densidade de volume das células α foi de (25,8%, 14,7, 16,2%), células β (35,5%, 8,7%, 54,8%) e células δ (3,9%, 6,2%, 14,3%) nos morcegos P. personatus, A. geoffroyi e D. ecaudata, respectivamente. As diferenças observadas entre espécies nos diversos parâmetros analisados podem refletir diferenças inter-específicas, assim como adaptações morfológicas das espécies ao seus hábitos alimentaresCoordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES, Brasil.The aim of this work was study endocrine pancreas of bats with different feeding habits (hemataphagous D. ecaudata, nectarivorous A. Geoffroyi and insetivorous P. personatus) by histological, morphometric and stereological methods. Six animals was used in each group and they were collected in the caverna casa de Pedra (Sergipe). The pancreas was processed through routine histological techniques for paraffin embedding. Histologically, components of the exocrine pancreas (acini and their secretory ducts associated) and endocrine pancreas (pancreatic islet) were identified. Immunoreactive cells (IR) to insulin, glucagon and somatostatin were found isolated scattered in the exocrine pancreas and, in the tissue near the pancreatic ducts. It was also identified IR cells to insulin, glucagon and somatostatin. In the pancreatic islets, it was to indentifided cells with cytoplasmic processes. The total mass of pancreatic tissue in body weight does not exceed 0.6% and this relationship was higher in the insectivorous bats (0.6%) and lowest in nectarivorous bats (0.3%). The pancreatic islets diameter varied between species, being 88.16 μm in the nectararivorous bat, in the vampire bat at 56.94 μm and 40.47 μm in the insectivorous bat. The stereological analysis showed a volume density (Vv) of the endocrine pancreas of 3.4% in the insectivorous bat, 6.1% in the nectarivorous bat and 4.1%. in the vampire bat. The islet mass was 0.15 in the insectivorous bat, 0.24 in the nectarivorous bat and 0.48 in the vampire bat. The volume density of α cells was (25.8%, 14.7, 16.2%), β cells (35.5%, 8.7%, 54.8%) and δ cells (3.9 %, 6.2%, 14.3%) in the P. personatus, A. geoffroyi and D. ecaudata bats, respectively. The differences observed between species in the various parameters analyzed may reflect inter-specific differences, as well as morphological adaptations of species to their eating habits.application/pdfporUniversidade Federal Rural do Rio de JaneiroPrograma de Pós-Graduação em Biologia AnimalUFRRJBrasilInstituto de Ciências Biológicas e da SaúdeMorcegosilhotas pancreáticasestereologiaBatspancreatic isletsstereologyMorfologiaEstudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentaresHistological, morphometric and stereologic study of the endocrine pancreas in bats with different feeding habitsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisAguiar, L. M. S., W. R. Camargo, et al. Occurrence of whitewinged vampire bat, Diaemus youngi (Mammalia: Chiroptera), in the Cerrado of Distrito Federal, Brazil. Rev. Bras. Zool, v.23, n.3, p.893-896. 2006. Ahlgren, U., J. Jonsson, et al. 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J Microsc, Mar 7. 2011. Uieda, W. Comportamento alimentar de morcegos hematófagos ao atacar aves, caprinos e suínos, em condições de cativeiro. Programa de Pós-Graduação em Ecologia, Universidade Estadual de Campinas (UNICAMP), Campinas-SP, 1994. 178 p. Unger, R. H. e L. Orci. Glucagon and the A cell: physiology and pathophysiology (first two parts). N Engl J Med, v.304, n.25, Jun 18, p.1518-24. 1981. Vaillant, C. R. e P. K. Lund. Distribution of glucagon-like peptide I in canine and feline pancreas and gastrointestinal tract. J Histochem Cytochem, v.34, n.9, Sep, p.1117-21. 1986. 44 Warnock, G. L., K. D. Dabbs, et al. Critical mass of islets that function after implantation in a large mammalian. Horm Metab Res Suppl, v.25, p.156-61. 1990. Watanabe, T. e I. Nagatsu. Immunohistochemical colocalization of insulin, aromatic L-amino acid decarboxylase and dopamine beta-hydroxylase in islet B cells of chicken pancreas. Cell Tissue Res, v.263, n.1, Jan, p.131-6. 1991. Widmaier, E. P. e T. H. Kunz. Basal, diurnal, and stress-induced levels of glucose and glucocorticoids in captive bats. J Exp Zool, v.265, n.5, Apr 1, p.533-40. 1993. Wieczorek, G., A. Pospischil, et al. A comparative immunohistochemical study of pancreatic islets in laboratory animals (rats, dogs, minipigs, nonhuman primates). Exp Toxicol Pathol, v.50, n.3, Jun, p.151-72. 1998. Winter, Y., J. Lopez, et al. Ultraviolet vision in a bat. Nature, v.425, n.6958, Oct 9, p.612-4. 2003. Yalden, D. W. e P. A. Morris. The lives of bats 1975. 247 p. (Newton Abbot : David & Charles ) Yukawa, M., T. Takeuchi, et al. Proportions of Various Endocrine Cells in the Pancreatic Islets of Wood Mice (Apodemus speciosus) Anatomia, Histologia, Embryologia, v.28, n.1, p.13-16. 1999.https://tede.ufrrj.br/retrieve/62622/2011%20-%20Clarice%20Machado%20dos%20Santos.pdf.jpghttps://tede.ufrrj.br/jspui/handle/jspui/4051Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2020-10-21T13:21:01Z No. of bitstreams: 1 2011 - Clarice Machado dos Santos.pdf: 1877332 bytes, checksum: 3627f6c2c3ce8cc4818df6d550417232 (MD5)Made available in DSpace on 2020-10-21T13:21:01Z (GMT). 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| dc.title.por.fl_str_mv |
Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares |
| dc.title.alternative.eng.fl_str_mv |
Histological, morphometric and stereologic study of the endocrine pancreas in bats with different feeding habits |
| title |
Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares |
| spellingShingle |
Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares Santos, Clarice Machado dos Morcegos ilhotas pancreáticas estereologia Bats pancreatic islets stereology Morfologia |
| title_short |
Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares |
| title_full |
Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares |
| title_fullStr |
Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares |
| title_full_unstemmed |
Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares |
| title_sort |
Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares |
| author |
Santos, Clarice Machado dos |
| author_facet |
Santos, Clarice Machado dos |
| author_role |
author |
| dc.contributor.author.fl_str_mv |
Santos, Clarice Machado dos |
| dc.contributor.advisor1.fl_str_mv |
Sales, Armando |
| dc.contributor.advisor1ID.fl_str_mv |
164050567-91 |
| dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/7306314893432986 |
| dc.contributor.referee1.fl_str_mv |
Pinheiro, Nadja Lima |
| dc.contributor.referee2.fl_str_mv |
Silva, Simone Florim da |
| dc.contributor.referee3.fl_str_mv |
Gitirana, Lycia de Brito |
| dc.contributor.referee4.fl_str_mv |
Mendes, Rosa Maria Marcos |
| dc.contributor.authorID.fl_str_mv |
086140217-04 |
| dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/6508425201201985 |
| contributor_str_mv |
Sales, Armando Pinheiro, Nadja Lima Silva, Simone Florim da Gitirana, Lycia de Brito Mendes, Rosa Maria Marcos |
| dc.subject.por.fl_str_mv |
Morcegos ilhotas pancreáticas estereologia |
| topic |
Morcegos ilhotas pancreáticas estereologia Bats pancreatic islets stereology Morfologia |
| dc.subject.eng.fl_str_mv |
Bats pancreatic islets stereology |
| dc.subject.cnpq.fl_str_mv |
Morfologia |
| description |
Este trabalho visou estudar o pâncreas endócrino de morcegos com diferentes hábitos alimentares (hematófago D. ecaudata, nectarívoro A. geoffroyi e insetívoro P. personatus), através de análise histológica, morfométrica e estereológica. Foram utilizados ao todo seis animais de cada grupo, coletados na caverna casa de Pedra (Sergipe). O pâncreas foi processado através das técnicas histológicas de rotina para inclusão em parafina. Histologicamente, foram identificado os componentes exócrinos (ácinos secretores e seus ductos associados) e endócrinos (ilhotas pancreáticas) do pâncreas. Foram observadas células imunoreativas (IR) à insulina, glucagon e somatostatina espalhadas isoladamente no pâncreas exócrino e, na região de tecido conjuntivo próximo aos ductos pancreáticos, foram identificadas células IR à insulina, glucagon e somatostatina. Células com a presença de processos citoplasmáticos foram visualizadas nas ilhotas. A massa de tecido pancreático total sobre a massa corporal não ultrapassa a relação de 0,6%, sendo esta relação maior nos morcegos insetívoros (0,6%) e menor nos morcegos nectarívoros (0,3%). O diâmetro das ilhotas variou entre as espécies sendo de 88,16 μm no morcego nectarívoro, de 56,94 μm no morcego hematófago e de 40,47 μm no morcego insetívoro. A análise estereológica mostrou uma densidade de volume (Vv) do pâncreas endócrino de 3,4% no morcego insetívoro, 6,1% no morcego nectarívoro e de 4,1% no morcego hematófago. A massa das ilhotas foi de 0,15 no morcego insetívoro, 0,24 no morcego nectarívoro e 0,48 no morcego hematófago. A densidade de volume das células α foi de (25,8%, 14,7, 16,2%), células β (35,5%, 8,7%, 54,8%) e células δ (3,9%, 6,2%, 14,3%) nos morcegos P. personatus, A. geoffroyi e D. ecaudata, respectivamente. As diferenças observadas entre espécies nos diversos parâmetros analisados podem refletir diferenças inter-específicas, assim como adaptações morfológicas das espécies ao seus hábitos alimentares |
| publishDate |
2011 |
| dc.date.issued.fl_str_mv |
2011-05-04 |
| dc.date.accessioned.fl_str_mv |
2023-12-21T18:35:58Z |
| dc.date.available.fl_str_mv |
2023-12-21T18:35:58Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
| format |
doctoralThesis |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
SANTOS, Clarice Machado dos. Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares. 2011. 44 f. Tese (Doutorado em Biologia Animal) - Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica - RJ, 2011. |
| dc.identifier.uri.fl_str_mv |
https://rima.ufrrj.br/jspui/handle/20.500.14407/9180 |
| identifier_str_mv |
SANTOS, Clarice Machado dos. Estudo histológico, morfométrico e estereológico do pâncreas endócrino em morcegos com diferentes hábitos alimentares. 2011. 44 f. Tese (Doutorado em Biologia Animal) - Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica - RJ, 2011. |
| url |
https://rima.ufrrj.br/jspui/handle/20.500.14407/9180 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.references.por.fl_str_mv |
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