Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | https://ri.ufs.br/handle/riufs/1971 |
Resumo: | Objective: To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods: A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results: Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions: Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients._________________________________________________________________________________________ RESUMO: Objetivo: Investigar o resultado cirúrgico da epilepsia do lobo temporal associada à esclerose hipocampal (TLE-HS) e neurocisticercose (NCC). Métodos: Estudo retrospectivo realizado em um centro de epilepsia. Resultados: Cinqüenta e dois pacientes (71,2%) com 10 anos ou menos de epilepsia antes da cirurgia tornaram-se livres de crises após um ano da operação, enquanto que 27 (50,0%) com mais de dez anos tornaram-se livres de crises após a cirurgia (p = 0,0121). Quarenta e três pacientes (72,9%), com três ou menos lobos afetados pela NCC tornaram-se livres de crises após um ano de operação, enquanto que 36 pacientes (52,9%) com mais de três lobos envolvidos estavam livres de crises após a cirurgia (p = 0,0163). Conclusão: A duração mais longa da epilepsia e o envolvimento de múltiplos lobos prevê pior resultado após a cirurgia para TLE-HS mais NCC. |
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Meguins, Lucas CrociatiAdry, Rodrigo Antonio Rocha da CruzSilva Junior, Sebastião Carlos daPereira, Carlos UmbertoOliveira, Jean Goncalves deMorais, Dionei Freitas deAraujo Filho, Gerardo Maria deMarques, Lúcia Helena Neves2017-02-23T19:55:07Z2017-02-23T19:55:07Z2015-12MEGUINS, L. C. et al. Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 12, p. 1014-1018, dez. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001201014>. Acesso em: 23 fev. 2017.1678-4227https://ri.ufs.br/handle/riufs/1971Creative Commons Atribuição 4.0 InternacionalObjective: To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods: A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results: Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions: Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients._________________________________________________________________________________________ RESUMO: Objetivo: Investigar o resultado cirúrgico da epilepsia do lobo temporal associada à esclerose hipocampal (TLE-HS) e neurocisticercose (NCC). Métodos: Estudo retrospectivo realizado em um centro de epilepsia. Resultados: Cinqüenta e dois pacientes (71,2%) com 10 anos ou menos de epilepsia antes da cirurgia tornaram-se livres de crises após um ano da operação, enquanto que 27 (50,0%) com mais de dez anos tornaram-se livres de crises após a cirurgia (p = 0,0121). Quarenta e três pacientes (72,9%), com três ou menos lobos afetados pela NCC tornaram-se livres de crises após um ano de operação, enquanto que 36 pacientes (52,9%) com mais de três lobos envolvidos estavam livres de crises após a cirurgia (p = 0,0163). Conclusão: A duração mais longa da epilepsia e o envolvimento de múltiplos lobos prevê pior resultado após a cirurgia para TLE-HS mais NCC.Academia Brasileira de Neurologia - ABNEUROTemporal lobe epilepsyHippocampal sclerosisNeurocysticercosisEpilepsia do lobo temporalEsclerose hipocampalNeurocisticercoseLonger epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosisLonga duração de epilepsia e envolvimento de múltiplos lobos são fatores preditivos de pior controle das crises convulsivas em pacientes com epilepsia refratária do lobo temporal associada a neurocisticercoseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILEpilepsyLobePatientsNeurocysticercosis.pdf.jpgEpilepsyLobePatientsNeurocysticercosis.pdf.jpgGenerated Thumbnailimage/jpeg1748https://ri.ufs.br/jspui/bitstream/riufs/1971/4/EpilepsyLobePatientsNeurocysticercosis.pdf.jpgd4884fc69b9c3b9cc9f72eb8c6987c46MD54ORIGINALEpilepsyLobePatientsNeurocysticercosis.pdfEpilepsyLobePatientsNeurocysticercosis.pdfapplication/pdf138240https://ri.ufs.br/jspui/bitstream/riufs/1971/1/EpilepsyLobePatientsNeurocysticercosis.pdfa6b22eb9c3e666792d7ef105487d8ea6MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1971/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTEpilepsyLobePatientsNeurocysticercosis.pdf.txtEpilepsyLobePatientsNeurocysticercosis.pdf.txtExtracted texttext/plain22669https://ri.ufs.br/jspui/bitstream/riufs/1971/3/EpilepsyLobePatientsNeurocysticercosis.pdf.txtd678c740e4dc31202f9c0173d875b19cMD53riufs/19712017-02-24 02:00:23.088oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-02-24T05:00:23Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.pt_BR.fl_str_mv |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis |
dc.title.alternative.pt_BR.fl_str_mv |
Longa duração de epilepsia e envolvimento de múltiplos lobos são fatores preditivos de pior controle das crises convulsivas em pacientes com epilepsia refratária do lobo temporal associada a neurocisticercose |
title |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis |
spellingShingle |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis Meguins, Lucas Crociati Temporal lobe epilepsy Hippocampal sclerosis Neurocysticercosis Epilepsia do lobo temporal Esclerose hipocampal Neurocisticercose |
title_short |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis |
title_full |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis |
title_fullStr |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis |
title_full_unstemmed |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis |
title_sort |
Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis |
author |
Meguins, Lucas Crociati |
author_facet |
Meguins, Lucas Crociati Adry, Rodrigo Antonio Rocha da Cruz Silva Junior, Sebastião Carlos da Pereira, Carlos Umberto Oliveira, Jean Goncalves de Morais, Dionei Freitas de Araujo Filho, Gerardo Maria de Marques, Lúcia Helena Neves |
author_role |
author |
author2 |
Adry, Rodrigo Antonio Rocha da Cruz Silva Junior, Sebastião Carlos da Pereira, Carlos Umberto Oliveira, Jean Goncalves de Morais, Dionei Freitas de Araujo Filho, Gerardo Maria de Marques, Lúcia Helena Neves |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Meguins, Lucas Crociati Adry, Rodrigo Antonio Rocha da Cruz Silva Junior, Sebastião Carlos da Pereira, Carlos Umberto Oliveira, Jean Goncalves de Morais, Dionei Freitas de Araujo Filho, Gerardo Maria de Marques, Lúcia Helena Neves |
dc.subject.por.fl_str_mv |
Temporal lobe epilepsy Hippocampal sclerosis Neurocysticercosis Epilepsia do lobo temporal Esclerose hipocampal Neurocisticercose |
topic |
Temporal lobe epilepsy Hippocampal sclerosis Neurocysticercosis Epilepsia do lobo temporal Esclerose hipocampal Neurocisticercose |
description |
Objective: To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods: A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results: Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions: Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients._________________________________________________________________________________________ RESUMO: Objetivo: Investigar o resultado cirúrgico da epilepsia do lobo temporal associada à esclerose hipocampal (TLE-HS) e neurocisticercose (NCC). Métodos: Estudo retrospectivo realizado em um centro de epilepsia. Resultados: Cinqüenta e dois pacientes (71,2%) com 10 anos ou menos de epilepsia antes da cirurgia tornaram-se livres de crises após um ano da operação, enquanto que 27 (50,0%) com mais de dez anos tornaram-se livres de crises após a cirurgia (p = 0,0121). Quarenta e três pacientes (72,9%), com três ou menos lobos afetados pela NCC tornaram-se livres de crises após um ano de operação, enquanto que 36 pacientes (52,9%) com mais de três lobos envolvidos estavam livres de crises após a cirurgia (p = 0,0163). Conclusão: A duração mais longa da epilepsia e o envolvimento de múltiplos lobos prevê pior resultado após a cirurgia para TLE-HS mais NCC. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-12 |
dc.date.accessioned.fl_str_mv |
2017-02-23T19:55:07Z |
dc.date.available.fl_str_mv |
2017-02-23T19:55:07Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MEGUINS, L. C. et al. Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 12, p. 1014-1018, dez. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001201014>. Acesso em: 23 fev. 2017. |
dc.identifier.uri.fl_str_mv |
https://ri.ufs.br/handle/riufs/1971 |
dc.identifier.issn.none.fl_str_mv |
1678-4227 |
dc.identifier.license.pt_BR.fl_str_mv |
Creative Commons Atribuição 4.0 Internacional |
identifier_str_mv |
MEGUINS, L. C. et al. Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 12, p. 1014-1018, dez. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001201014>. Acesso em: 23 fev. 2017. 1678-4227 Creative Commons Atribuição 4.0 Internacional |
url |
https://ri.ufs.br/handle/riufs/1971 |
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eng |
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eng |
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openAccess |
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Academia Brasileira de Neurologia - ABNEURO |
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Academia Brasileira de Neurologia - ABNEURO |
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