Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis

Detalhes bibliográficos
Autor(a) principal: Meguins, Lucas Crociati
Data de Publicação: 2015
Outros Autores: Adry, Rodrigo Antonio Rocha da Cruz, Silva Junior, Sebastião Carlos da, Pereira, Carlos Umberto, Oliveira, Jean Goncalves de, Morais, Dionei Freitas de, Araujo Filho, Gerardo Maria de, Marques, Lúcia Helena Neves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/handle/riufs/1971
Resumo: Objective: To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods: A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results: Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions: Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients._________________________________________________________________________________________ RESUMO: Objetivo: Investigar o resultado cirúrgico da epilepsia do lobo temporal associada à esclerose hipocampal (TLE-HS) e neurocisticercose (NCC). Métodos: Estudo retrospectivo realizado em um centro de epilepsia. Resultados: Cinqüenta e dois pacientes (71,2%) com 10 anos ou menos de epilepsia antes da cirurgia tornaram-se livres de crises após um ano da operação, enquanto que 27 (50,0%) com mais de dez anos tornaram-se livres de crises após a cirurgia (p = 0,0121). Quarenta e três pacientes (72,9%), com três ou menos lobos afetados pela NCC tornaram-se livres de crises após um ano de operação, enquanto que 36 pacientes (52,9%) com mais de três lobos envolvidos estavam livres de crises após a cirurgia (p = 0,0163). Conclusão: A duração mais longa da epilepsia e o envolvimento de múltiplos lobos prevê pior resultado após a cirurgia para TLE-HS mais NCC.
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spelling Meguins, Lucas CrociatiAdry, Rodrigo Antonio Rocha da CruzSilva Junior, Sebastião Carlos daPereira, Carlos UmbertoOliveira, Jean Goncalves deMorais, Dionei Freitas deAraujo Filho, Gerardo Maria deMarques, Lúcia Helena Neves2017-02-23T19:55:07Z2017-02-23T19:55:07Z2015-12MEGUINS, L. C. et al. Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 12, p. 1014-1018, dez. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001201014>. Acesso em: 23 fev. 2017.1678-4227https://ri.ufs.br/handle/riufs/1971Creative Commons Atribuição 4.0 InternacionalObjective: To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods: A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results: Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions: Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients._________________________________________________________________________________________ RESUMO: Objetivo: Investigar o resultado cirúrgico da epilepsia do lobo temporal associada à esclerose hipocampal (TLE-HS) e neurocisticercose (NCC). Métodos: Estudo retrospectivo realizado em um centro de epilepsia. Resultados: Cinqüenta e dois pacientes (71,2%) com 10 anos ou menos de epilepsia antes da cirurgia tornaram-se livres de crises após um ano da operação, enquanto que 27 (50,0%) com mais de dez anos tornaram-se livres de crises após a cirurgia (p = 0,0121). Quarenta e três pacientes (72,9%), com três ou menos lobos afetados pela NCC tornaram-se livres de crises após um ano de operação, enquanto que 36 pacientes (52,9%) com mais de três lobos envolvidos estavam livres de crises após a cirurgia (p = 0,0163). Conclusão: A duração mais longa da epilepsia e o envolvimento de múltiplos lobos prevê pior resultado após a cirurgia para TLE-HS mais NCC.Academia Brasileira de Neurologia - ABNEUROTemporal lobe epilepsyHippocampal sclerosisNeurocysticercosisEpilepsia do lobo temporalEsclerose hipocampalNeurocisticercoseLonger epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosisLonga duração de epilepsia e envolvimento de múltiplos lobos são fatores preditivos de pior controle das crises convulsivas em pacientes com epilepsia refratária do lobo temporal associada a neurocisticercoseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILEpilepsyLobePatientsNeurocysticercosis.pdf.jpgEpilepsyLobePatientsNeurocysticercosis.pdf.jpgGenerated Thumbnailimage/jpeg1748https://ri.ufs.br/jspui/bitstream/riufs/1971/4/EpilepsyLobePatientsNeurocysticercosis.pdf.jpgd4884fc69b9c3b9cc9f72eb8c6987c46MD54ORIGINALEpilepsyLobePatientsNeurocysticercosis.pdfEpilepsyLobePatientsNeurocysticercosis.pdfapplication/pdf138240https://ri.ufs.br/jspui/bitstream/riufs/1971/1/EpilepsyLobePatientsNeurocysticercosis.pdfa6b22eb9c3e666792d7ef105487d8ea6MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1971/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTEpilepsyLobePatientsNeurocysticercosis.pdf.txtEpilepsyLobePatientsNeurocysticercosis.pdf.txtExtracted texttext/plain22669https://ri.ufs.br/jspui/bitstream/riufs/1971/3/EpilepsyLobePatientsNeurocysticercosis.pdf.txtd678c740e4dc31202f9c0173d875b19cMD53riufs/19712017-02-24 02:00:23.088oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-02-24T05:00:23Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
dc.title.alternative.pt_BR.fl_str_mv Longa duração de epilepsia e envolvimento de múltiplos lobos são fatores preditivos de pior controle das crises convulsivas em pacientes com epilepsia refratária do lobo temporal associada a neurocisticercose
title Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
spellingShingle Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
Meguins, Lucas Crociati
Temporal lobe epilepsy
Hippocampal sclerosis
Neurocysticercosis
Epilepsia do lobo temporal
Esclerose hipocampal
Neurocisticercose
title_short Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
title_full Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
title_fullStr Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
title_full_unstemmed Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
title_sort Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis
author Meguins, Lucas Crociati
author_facet Meguins, Lucas Crociati
Adry, Rodrigo Antonio Rocha da Cruz
Silva Junior, Sebastião Carlos da
Pereira, Carlos Umberto
Oliveira, Jean Goncalves de
Morais, Dionei Freitas de
Araujo Filho, Gerardo Maria de
Marques, Lúcia Helena Neves
author_role author
author2 Adry, Rodrigo Antonio Rocha da Cruz
Silva Junior, Sebastião Carlos da
Pereira, Carlos Umberto
Oliveira, Jean Goncalves de
Morais, Dionei Freitas de
Araujo Filho, Gerardo Maria de
Marques, Lúcia Helena Neves
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Meguins, Lucas Crociati
Adry, Rodrigo Antonio Rocha da Cruz
Silva Junior, Sebastião Carlos da
Pereira, Carlos Umberto
Oliveira, Jean Goncalves de
Morais, Dionei Freitas de
Araujo Filho, Gerardo Maria de
Marques, Lúcia Helena Neves
dc.subject.por.fl_str_mv Temporal lobe epilepsy
Hippocampal sclerosis
Neurocysticercosis
Epilepsia do lobo temporal
Esclerose hipocampal
Neurocisticercose
topic Temporal lobe epilepsy
Hippocampal sclerosis
Neurocysticercosis
Epilepsia do lobo temporal
Esclerose hipocampal
Neurocisticercose
description Objective: To investigate the surgical outcomes of temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) and neurocysticercosis (NCC). Methods: A retrospective investigation of patients with TLE-HS was conducted in a tertiary center. Results: Seventy-nine (62.2%), 37 (29.1%), 6 (4.7%), and 5 (3.9%) patients were Engel class I, II, III, and IV, respectively. Fifty-two (71.2%) patients with epilepsy durations ≤ 10 years prior to surgery were seizure-free 1 year after the operation compared to 27 (50.0%) patients with epilepsy durations > 10 years (p = 0.0121). Forty-three (72.9%) patients with three or fewer lobes affected by NCC were seizure-free one year after the operation, and 36 (52.9%) patients with more than three involved lobes were seizure-free after surgery (p = 0.0163). Conclusions: Longer epilepsy durations and multiple lobe involvement predicted worse seizure outcomes in TLE-HS plus NCC patients._________________________________________________________________________________________ RESUMO: Objetivo: Investigar o resultado cirúrgico da epilepsia do lobo temporal associada à esclerose hipocampal (TLE-HS) e neurocisticercose (NCC). Métodos: Estudo retrospectivo realizado em um centro de epilepsia. Resultados: Cinqüenta e dois pacientes (71,2%) com 10 anos ou menos de epilepsia antes da cirurgia tornaram-se livres de crises após um ano da operação, enquanto que 27 (50,0%) com mais de dez anos tornaram-se livres de crises após a cirurgia (p = 0,0121). Quarenta e três pacientes (72,9%), com três ou menos lobos afetados pela NCC tornaram-se livres de crises após um ano de operação, enquanto que 36 pacientes (52,9%) com mais de três lobos envolvidos estavam livres de crises após a cirurgia (p = 0,0163). Conclusão: A duração mais longa da epilepsia e o envolvimento de múltiplos lobos prevê pior resultado após a cirurgia para TLE-HS mais NCC.
publishDate 2015
dc.date.issued.fl_str_mv 2015-12
dc.date.accessioned.fl_str_mv 2017-02-23T19:55:07Z
dc.date.available.fl_str_mv 2017-02-23T19:55:07Z
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dc.identifier.citation.fl_str_mv MEGUINS, L. C. et al. Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 12, p. 1014-1018, dez. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001201014>. Acesso em: 23 fev. 2017.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/handle/riufs/1971
dc.identifier.issn.none.fl_str_mv 1678-4227
dc.identifier.license.pt_BR.fl_str_mv Creative Commons Atribuição 4.0 Internacional
identifier_str_mv MEGUINS, L. C. et al. Longer epilepsy duration and multiple lobe involvement predict worse seizure outcomes for patients with refractory temporal lobe epilepsy associated with neurocysticercosis. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 12, p. 1014-1018, dez. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001201014>. Acesso em: 23 fev. 2017.
1678-4227
Creative Commons Atribuição 4.0 Internacional
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