Perfil laboratorial de pacientes com HIV acompanhados no Laboratório Central de Saúde Pública (LACEN) em Aracaju/Sergipe

• Autor(a) principal: Simões, Arianny Ferro
• Data de Publicação: 2017
• Outros Autores: Nascimento, Ana Carolina Silveira Soares
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UFS
• Texto Completo: http://ri.ufs.br/jspui/handle/riufs/10715
• topic: Farmácia; Ensino de farmácia; Pacientes; Laboratório Central de Saúde Pública (LACEN); SUS; HIV; Aracaju (SE); CIENCIAS DA SAUDE::MEDICINA::CLINICA MEDICA::DOENCAS INFECCIOSAS E PARASITARIAS

The existence of the HIV virus as the cause of the Acquired Immunodeficiency Syndrome (AIDS) has been known for some thirty years, and can be transmitted through sexual, vertical (maternal) or blood. In Brazil, from the beginning of the AIDS or AIDS epidemic until June 2015, there were some 798,366 cases of the disease, showing a linear trend in the increase of infection in less developed regions such as the North-Northeast with prevalence among the young and the elderly. The greatest challenge faced by the clinical staff in seropositive patients is the appearance of resistance to antiretroviral therapy (ART), which may lead to worsening of the disease with evolution to the death of these patients. Considering this, this study aims to evaluate the incidence of seropositives for the HIV virus in the state of Sergipe and its adherence to antiretroviral treatment, with an emphasis on resistance to ART, if any. For this, we conducted a descriptive, observational, retrospective study based on the collection of data from 40 medical records, from the System of Control of Laboratory Tests (Siscel) and Genotyping System (Sisgeno), of HIV seropositive patients. Of the total number of records analyzed, twenty-one individuals (55%) were male and nineteen individuals (48%) were female. The mean age of the patients was 37 years. Regarding the CD4 and CD8 T lymphocyte counts, we observed that CD8 T lymphocytes predominate in number in relation to T-CD4 in both sexes. In the evaluation of the genotyping tests, it was verified that the occurrence of antiretroviral resistance was greater in males, and these data are corroborated by the higher mean viral load in males compared to females. Considering this, we can conclude that men are more susceptible to the complicationssuch as resistance, immunosuppression,which are induced by the failure of the ART, being necessary actions with focus in this patient, aiming at the improvement of their quality of life.