Extrato hidroetanólico da entrecasca da S. Cumini (L.) skeels reduz o estresse oxidativo de ratos wistar submetidos ao treinamento de natação intervalado de alta intensidade

• Autor(a) principal: Costa, Rôas de Araujo
• Data de Publicação: 2017
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da UFS
• Texto Completo: https://ri.ufs.br/handle/riufs/6835
• topic: Fisiologia; Stress oxidativo; Estresse oxidativo; Syzygium; Exercícios físicos; Produtos naturais; Syzygium cumini; HIIT; Antioxidantes; Antioxidants; Oxidative stress; Natural products; CIENCIAS BIOLOGICAS::FISIOLOGIA

High intensity and / or exhaustive physical exercise may induce oxidative stress in athletes as well as in physically active or sedentary individuals. In this way the use of antioxidants appears as an alternative to prevent or mitigate this effect. Syzygium cumini (L.) Skeels, commonly known as jambolan, is a species found in tropical regions and is a species rich in phenolic compounds with potential antioxidant activity. The main objective of the study was to evaluate the effect of 21 days of supplementation with S. cumini hydroethanolic extract (EHE) in animals submitted to a protocol of 3 weeks of high intensity interval training (HIIT), 5 sessions per week. In this manner, wistar rats (250-300g) (CEPA: 58/2016) were used. The animals were randomly divided into 5 groups (n = 10): Sedentary (GC), sedentary animals treated with EHE (GEHE), animals submitted to high intensity interval training (HIIT) With EHE (GE + EHE) and animals submitted to (HIIT) and treated with quercetin (GE + Q). The results showed that EHE treatment was effective in reducing oxidative damage in the evaluated tissues: GT: 14.49 ± 1.78 vs GT + EHE: 8.16 ± 0.54 nmol EqMDA / mL of blood in the muscle ( GT: 9.61 ± 1.51 vs. GT + EHE 7.46 ± 0.69 nmol EqMDA / mg of liver), liver (GT: 40.85 ± 7.05 vs. GT + EHE: 19.97 ± 5, 95 nmol EqMDA / mg tissue) and heart (GT: 18.06 ± 2.88 vs. 12.64 ± 2.37 nmol EqMDA / mg tissue), while for the quantification of sulfhydryl groups the EHE treated animals had their Preserved thiols groups. Thus, it was concluded that daily treatment for 21 days with EHE was able to attenuate oxidative damage in wistar rats submitted to a HIIT protocol for 3 weeks.