Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos

Detalhes bibliográficos
Autor(a) principal: Almeida, Fernando Henrique Oliveira de
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/jspui/handle/riufs/18090
Resumo: Obesity is a complex disease with a multifactorial etiology. It is the second most common cause of preventable death after smoking. The increase in overweight and obesity in the world is evident in studies, with data from more than 19.2 million adults in 186 countries. Complementary and alternative therapies have been used for many years, but recently they are being used more and more around the world. Due to the high costs of synthetic drugs to control obesity and their adverse effects, the use of medicinal plants and herbal medicines has been gaining ground in weight control. The present work aimed to map scientific evidence about medicinal plants with therapeutic properties in the treatment of obesity and their efficacy and safety for the patient. To carry out the review, 292 articles were identified, of which after evaluation and literature, only 24 articles fit the inclusion criteria and were used in the systematic review. The results of this systematic review demonstrate the effectiveness of phytotherapy and medicinal plants for the treatment of obesity and metabolic syndrome, but it also demonstrated a great fragility concerning studies focused on patient safety. In the future, it becomes necessary to standardize studies focused on the efficacy and safety of medicinal plants and herbal medicines in obesity, in order to ensure that the product being used in therapy is of good quality, safe, with minimal side effects for the patient.
id UFS-2_bb57665d31475094e9b17972c145af3f
oai_identifier_str oai:ufs.br:riufs/18090
network_acronym_str UFS-2
network_name_str Repositório Institucional da UFS
repository_id_str
spelling Almeida, Fernando Henrique Oliveira deAntoniolli, Angelo Roberto2023-08-11T23:08:51Z2023-08-11T23:08:51Z2019-01-31ALMEIDA, Fernando Henrique Oliveira de. Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos. 2019. 65 f. Dissertação (Mestrado em Ciências Farmacêuticas) – Universidade Federal de Sergipe, São Cristóvão, 2019.https://ri.ufs.br/jspui/handle/riufs/18090Obesity is a complex disease with a multifactorial etiology. It is the second most common cause of preventable death after smoking. The increase in overweight and obesity in the world is evident in studies, with data from more than 19.2 million adults in 186 countries. Complementary and alternative therapies have been used for many years, but recently they are being used more and more around the world. Due to the high costs of synthetic drugs to control obesity and their adverse effects, the use of medicinal plants and herbal medicines has been gaining ground in weight control. The present work aimed to map scientific evidence about medicinal plants with therapeutic properties in the treatment of obesity and their efficacy and safety for the patient. To carry out the review, 292 articles were identified, of which after evaluation and literature, only 24 articles fit the inclusion criteria and were used in the systematic review. The results of this systematic review demonstrate the effectiveness of phytotherapy and medicinal plants for the treatment of obesity and metabolic syndrome, but it also demonstrated a great fragility concerning studies focused on patient safety. In the future, it becomes necessary to standardize studies focused on the efficacy and safety of medicinal plants and herbal medicines in obesity, in order to ensure that the product being used in therapy is of good quality, safe, with minimal side effects for the patient.A obesidade é uma doença complexa e de etiologia multifatorial. É a segunda causa mais comum de morte evitável depois do tabagismo. O aumento do sobrepeso e da obesidade no mundo fica evidente em estudos, com dados de mais de 19,2 milhões de adultos em 186 países. Terapias complementares e alternativas são usadas há muito anos, mas recentemente estão sendo usadas cada vez mais em todo o mundo. Devido aos altos custos com drogas sintéticas para o controle da obesidade e seus efeitos adversos, a utilização de plantas medicinais e fitoterápicos vem ganhando espaço no controle do peso. O presente trabalho objetivou mapear evidências científicas acerca de plantas medicinais com propriedades terapêuticas no tratamento da obesidade e a sua eficácia e segurança para o paciente. Para a realização da revisão foram identificados 292 artigos, dos quais após avaliação e literatura, apenas 24 artigos se encaixam com os critérios de inclusão e foram utilizados na revisão sistemática. Os resultados desta revisão sistemática demonstram a eficácia da fitoterapia e plantas medicinais para o tratamento da obesidade e da síndrome metabólica, mas demonstrou também uma grande fragilidade no que se diz a respeito de estudos voltados à segurança ao paciente. No futuro, se torna necessário padronizar os estudos voltados para eficácia e segurança de plantas medicinais e fitoterápicos na obesidade, visando garantir que o produto que está sendo utilizado na terapia seja de qualidade, seguro, com o mínimo de efeitos colaterais para o paciente.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESSão CristóvãoporCiências farmacêuticasObesidadePlantas medicinaisMatéria médica vegetalEnsaio clínicoFitoterápicosRevisão sistemáticaClinical trialHerbal medicinesObesityMedicinal plantsSystematic reviewCIENCIAS BIOLOGICAS::FARMACOLOGIAPlantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicosMedicinal plants used in the treatment of obesity: systematic review of clinical trialsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisPós-Graduação em Ciências FarmacêuticasUniversidade Federal de Sergipe (UFS)reponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/18090/1/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD51ORIGINALFERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdfFERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdfapplication/pdf1499334https://ri.ufs.br/jspui/bitstream/riufs/18090/2/FERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf64437c77e52d38e8535b4ced8b25ae14MD52TEXTFERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf.txtFERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf.txtExtracted texttext/plain103854https://ri.ufs.br/jspui/bitstream/riufs/18090/3/FERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf.txta34b5bb27ee311827d054ab5e5fb82e2MD53THUMBNAILFERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf.jpgFERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf.jpgGenerated Thumbnailimage/jpeg1296https://ri.ufs.br/jspui/bitstream/riufs/18090/4/FERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf.jpg691df3f40a70f4e22070af272d8809e0MD54riufs/180902023-08-11 20:08:57.958oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2023-08-11T23:08:57Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos
dc.title.alternative.eng.fl_str_mv Medicinal plants used in the treatment of obesity: systematic review of clinical trials
title Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos
spellingShingle Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos
Almeida, Fernando Henrique Oliveira de
Ciências farmacêuticas
Obesidade
Plantas medicinais
Matéria médica vegetal
Ensaio clínico
Fitoterápicos
Revisão sistemática
Clinical trial
Herbal medicines
Obesity
Medicinal plants
Systematic review
CIENCIAS BIOLOGICAS::FARMACOLOGIA
title_short Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos
title_full Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos
title_fullStr Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos
title_full_unstemmed Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos
title_sort Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos
author Almeida, Fernando Henrique Oliveira de
author_facet Almeida, Fernando Henrique Oliveira de
author_role author
dc.contributor.author.fl_str_mv Almeida, Fernando Henrique Oliveira de
dc.contributor.advisor1.fl_str_mv Antoniolli, Angelo Roberto
contributor_str_mv Antoniolli, Angelo Roberto
dc.subject.por.fl_str_mv Ciências farmacêuticas
Obesidade
Plantas medicinais
Matéria médica vegetal
Ensaio clínico
Fitoterápicos
Revisão sistemática
Clinical trial
Herbal medicines
Obesity
Medicinal plants
Systematic review
topic Ciências farmacêuticas
Obesidade
Plantas medicinais
Matéria médica vegetal
Ensaio clínico
Fitoterápicos
Revisão sistemática
Clinical trial
Herbal medicines
Obesity
Medicinal plants
Systematic review
CIENCIAS BIOLOGICAS::FARMACOLOGIA
dc.subject.cnpq.fl_str_mv CIENCIAS BIOLOGICAS::FARMACOLOGIA
description Obesity is a complex disease with a multifactorial etiology. It is the second most common cause of preventable death after smoking. The increase in overweight and obesity in the world is evident in studies, with data from more than 19.2 million adults in 186 countries. Complementary and alternative therapies have been used for many years, but recently they are being used more and more around the world. Due to the high costs of synthetic drugs to control obesity and their adverse effects, the use of medicinal plants and herbal medicines has been gaining ground in weight control. The present work aimed to map scientific evidence about medicinal plants with therapeutic properties in the treatment of obesity and their efficacy and safety for the patient. To carry out the review, 292 articles were identified, of which after evaluation and literature, only 24 articles fit the inclusion criteria and were used in the systematic review. The results of this systematic review demonstrate the effectiveness of phytotherapy and medicinal plants for the treatment of obesity and metabolic syndrome, but it also demonstrated a great fragility concerning studies focused on patient safety. In the future, it becomes necessary to standardize studies focused on the efficacy and safety of medicinal plants and herbal medicines in obesity, in order to ensure that the product being used in therapy is of good quality, safe, with minimal side effects for the patient.
publishDate 2019
dc.date.issued.fl_str_mv 2019-01-31
dc.date.accessioned.fl_str_mv 2023-08-11T23:08:51Z
dc.date.available.fl_str_mv 2023-08-11T23:08:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv ALMEIDA, Fernando Henrique Oliveira de. Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos. 2019. 65 f. Dissertação (Mestrado em Ciências Farmacêuticas) – Universidade Federal de Sergipe, São Cristóvão, 2019.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/jspui/handle/riufs/18090
identifier_str_mv ALMEIDA, Fernando Henrique Oliveira de. Plantas medicinais utilizadas no tratamento da obesidade: revisão sistemática de ensaios clínicos. 2019. 65 f. Dissertação (Mestrado em Ciências Farmacêuticas) – Universidade Federal de Sergipe, São Cristóvão, 2019.
url https://ri.ufs.br/jspui/handle/riufs/18090
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.program.fl_str_mv Pós-Graduação em Ciências Farmacêuticas
dc.publisher.initials.fl_str_mv Universidade Federal de Sergipe (UFS)
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFS
instname:Universidade Federal de Sergipe (UFS)
instacron:UFS
instname_str Universidade Federal de Sergipe (UFS)
instacron_str UFS
institution UFS
reponame_str Repositório Institucional da UFS
collection Repositório Institucional da UFS
bitstream.url.fl_str_mv https://ri.ufs.br/jspui/bitstream/riufs/18090/1/license.txt
https://ri.ufs.br/jspui/bitstream/riufs/18090/2/FERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf
https://ri.ufs.br/jspui/bitstream/riufs/18090/3/FERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf.txt
https://ri.ufs.br/jspui/bitstream/riufs/18090/4/FERNANDO_HENRIQUE_OLIVEIRA_ALMEIDA.pdf.jpg
bitstream.checksum.fl_str_mv 098cbbf65c2c15e1fb2e49c5d306a44c
64437c77e52d38e8535b4ced8b25ae14
a34b5bb27ee311827d054ab5e5fb82e2
691df3f40a70f4e22070af272d8809e0
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)
repository.mail.fl_str_mv repositorio@academico.ufs.br
_version_ 1802110676155498496