Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography

Detalhes bibliográficos
Autor(a) principal: Sousa, Antônio Carlos Sobral
Data de Publicação: 2007
Outros Autores: Oliveira, Joselina Luzia Menezes, Goes, Thiago Jônatas Santos, Santana, Thaiana Aragão, Travassos, Thiago Figueiredo, Teles, Lívia Dantas, Andrade, Fernando Diego Anjos de, Nascimento Júnior, Adão Cardoso do, Alves, Érica Oliveira, Barreto, Martha Azevedo, Barreto Filho, José Augusto Soares, D'Oliveira Júnior, Argemiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/handle/riufs/1296
Resumo: Background Exercise echocardiography (EE) is an established method to diagnose coronary artery disease (CAD). Chronotropic incompetence (CI) during the EE may be a marker of myocardial ischemia. The purpose of this investigation was to evaluate the additive value of CI during EE in CAD diagnosis. Methods Between 2000 and 2006, 4042 patients (1900 men with a mean age of 56 ± 11 years) were evaluated by EE. Based on the heart rate (HR) reached during the exercise test, the subjects were divided into two groups: G1 group – 490 patients who failed to achieve 85% of the maximal age-predicted HR, and G2 group – 3552 patients who were able to achieve 85% of the maximal age-predicted HR. Clinical characteristics, left ventricular wall motion abnormalities – wall motion score index (WMSI) – and coronary angiography (CA) were the parameters compared between the two groups. Results The left ventricular wall motion abnormalities were more frequent in G1 group than in G2 group (54% versus 26%; P < 0.00001). WMSI was higher in G1 group than in G2 group, both at rest (1.06 ± 0.17 versus 1.02 ± 0.09; P < 0.0001) and after exercise (1.12 ± 0.23 versus 1.04 ± 0.21; P < 0.0001). In G1 group, 82% of the patients with positive EE for myocardial ischemia presented obstructive coronary, compared to 71% (P = 0.03) in G2 group. Conclusion CI is associated with a higher frequency of myocardial ischemia during EE, reinforcing the concept that CI is a marker of the severity of myocardial ischemia.
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spelling Sousa, Antônio Carlos SobralOliveira, Joselina Luzia MenezesGoes, Thiago Jônatas SantosSantana, Thaiana AragãoTravassos, Thiago FigueiredoTeles, Lívia DantasAndrade, Fernando Diego Anjos deNascimento Júnior, Adão Cardoso doAlves, Érica OliveiraBarreto, Martha AzevedoBarreto Filho, José Augusto SoaresD'Oliveira Júnior, Argemiro2014-10-06T19:46:15Z2014-10-06T19:46:15Z2007OLIVEIRA, J. L. M. et. al. Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography. Cardiovascular Ultrasound, Roma, v. 5, n. 38, 2007. Disponível em: <http://www.dx.doi.org/10.1186/1476-7120-5-38>. Acesso em: 06 out. 2014.https://ri.ufs.br/handle/riufs/1296Creative Commons Attribution License 4.0Background Exercise echocardiography (EE) is an established method to diagnose coronary artery disease (CAD). Chronotropic incompetence (CI) during the EE may be a marker of myocardial ischemia. The purpose of this investigation was to evaluate the additive value of CI during EE in CAD diagnosis. Methods Between 2000 and 2006, 4042 patients (1900 men with a mean age of 56 ± 11 years) were evaluated by EE. Based on the heart rate (HR) reached during the exercise test, the subjects were divided into two groups: G1 group – 490 patients who failed to achieve 85% of the maximal age-predicted HR, and G2 group – 3552 patients who were able to achieve 85% of the maximal age-predicted HR. Clinical characteristics, left ventricular wall motion abnormalities – wall motion score index (WMSI) – and coronary angiography (CA) were the parameters compared between the two groups. Results The left ventricular wall motion abnormalities were more frequent in G1 group than in G2 group (54% versus 26%; P < 0.00001). WMSI was higher in G1 group than in G2 group, both at rest (1.06 ± 0.17 versus 1.02 ± 0.09; P < 0.0001) and after exercise (1.12 ± 0.23 versus 1.04 ± 0.21; P < 0.0001). In G1 group, 82% of the patients with positive EE for myocardial ischemia presented obstructive coronary, compared to 71% (P = 0.03) in G2 group. Conclusion CI is associated with a higher frequency of myocardial ischemia during EE, reinforcing the concept that CI is a marker of the severity of myocardial ischemia.BioMed Central Ltd.EcocardiografiaDoença Arterial CoronarianaIncompetência CronotrópicaDoença cardiovascularChronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiographyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILChronotropicIncompetence.pdf.jpgChronotropicIncompetence.pdf.jpgGenerated Thumbnailimage/jpeg1774https://ri.ufs.br/jspui/bitstream/riufs/1296/4/ChronotropicIncompetence.pdf.jpg9d687615b18e1d5046de2ba5f98640c9MD54ORIGINALChronotropicIncompetence.pdfChronotropicIncompetence.pdfapplication/pdf359481https://ri.ufs.br/jspui/bitstream/riufs/1296/1/ChronotropicIncompetence.pdf7552dfd93916e1c42ba4cc78c511020bMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1296/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTChronotropicIncompetence.pdf.txtChronotropicIncompetence.pdf.txtExtracted texttext/plain36275https://ri.ufs.br/jspui/bitstream/riufs/1296/3/ChronotropicIncompetence.pdf.txt68f14ff829125252f7a6ee34af3a4e1bMD53riufs/12962016-01-26 08:00:57.664oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2016-01-26T11:00:57Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography
title Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography
spellingShingle Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography
Sousa, Antônio Carlos Sobral
Ecocardiografia
Doença Arterial Coronariana
Incompetência Cronotrópica
Doença cardiovascular
title_short Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography
title_full Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography
title_fullStr Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography
title_full_unstemmed Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography
title_sort Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography
author Sousa, Antônio Carlos Sobral
author_facet Sousa, Antônio Carlos Sobral
Oliveira, Joselina Luzia Menezes
Goes, Thiago Jônatas Santos
Santana, Thaiana Aragão
Travassos, Thiago Figueiredo
Teles, Lívia Dantas
Andrade, Fernando Diego Anjos de
Nascimento Júnior, Adão Cardoso do
Alves, Érica Oliveira
Barreto, Martha Azevedo
Barreto Filho, José Augusto Soares
D'Oliveira Júnior, Argemiro
author_role author
author2 Oliveira, Joselina Luzia Menezes
Goes, Thiago Jônatas Santos
Santana, Thaiana Aragão
Travassos, Thiago Figueiredo
Teles, Lívia Dantas
Andrade, Fernando Diego Anjos de
Nascimento Júnior, Adão Cardoso do
Alves, Érica Oliveira
Barreto, Martha Azevedo
Barreto Filho, José Augusto Soares
D'Oliveira Júnior, Argemiro
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Sousa, Antônio Carlos Sobral
Oliveira, Joselina Luzia Menezes
Goes, Thiago Jônatas Santos
Santana, Thaiana Aragão
Travassos, Thiago Figueiredo
Teles, Lívia Dantas
Andrade, Fernando Diego Anjos de
Nascimento Júnior, Adão Cardoso do
Alves, Érica Oliveira
Barreto, Martha Azevedo
Barreto Filho, José Augusto Soares
D'Oliveira Júnior, Argemiro
dc.subject.por.fl_str_mv Ecocardiografia
Doença Arterial Coronariana
Incompetência Cronotrópica
Doença cardiovascular
topic Ecocardiografia
Doença Arterial Coronariana
Incompetência Cronotrópica
Doença cardiovascular
description Background Exercise echocardiography (EE) is an established method to diagnose coronary artery disease (CAD). Chronotropic incompetence (CI) during the EE may be a marker of myocardial ischemia. The purpose of this investigation was to evaluate the additive value of CI during EE in CAD diagnosis. Methods Between 2000 and 2006, 4042 patients (1900 men with a mean age of 56 ± 11 years) were evaluated by EE. Based on the heart rate (HR) reached during the exercise test, the subjects were divided into two groups: G1 group – 490 patients who failed to achieve 85% of the maximal age-predicted HR, and G2 group – 3552 patients who were able to achieve 85% of the maximal age-predicted HR. Clinical characteristics, left ventricular wall motion abnormalities – wall motion score index (WMSI) – and coronary angiography (CA) were the parameters compared between the two groups. Results The left ventricular wall motion abnormalities were more frequent in G1 group than in G2 group (54% versus 26%; P < 0.00001). WMSI was higher in G1 group than in G2 group, both at rest (1.06 ± 0.17 versus 1.02 ± 0.09; P < 0.0001) and after exercise (1.12 ± 0.23 versus 1.04 ± 0.21; P < 0.0001). In G1 group, 82% of the patients with positive EE for myocardial ischemia presented obstructive coronary, compared to 71% (P = 0.03) in G2 group. Conclusion CI is associated with a higher frequency of myocardial ischemia during EE, reinforcing the concept that CI is a marker of the severity of myocardial ischemia.
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2014-10-06T19:46:15Z
dc.date.available.fl_str_mv 2014-10-06T19:46:15Z
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dc.identifier.citation.fl_str_mv OLIVEIRA, J. L. M. et. al. Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography. Cardiovascular Ultrasound, Roma, v. 5, n. 38, 2007. Disponível em: <http://www.dx.doi.org/10.1186/1476-7120-5-38>. Acesso em: 06 out. 2014.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/handle/riufs/1296
dc.identifier.license.pt_BR.fl_str_mv Creative Commons Attribution License 4.0
identifier_str_mv OLIVEIRA, J. L. M. et. al. Chronotropic incompetence and a higher frequency of myocardial ischemia in exercise echocardiography. Cardiovascular Ultrasound, Roma, v. 5, n. 38, 2007. Disponível em: <http://www.dx.doi.org/10.1186/1476-7120-5-38>. Acesso em: 06 out. 2014.
Creative Commons Attribution License 4.0
url https://ri.ufs.br/handle/riufs/1296
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv BioMed Central Ltd.
publisher.none.fl_str_mv BioMed Central Ltd.
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