Ocular melanoma: keep your eyes open for late brain metastases
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | https://ri.ufs.br/handle/riufs/2066 |
Resumo: | Background:The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. Case Description:The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. Conclusion:The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed. |
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Silva, Danilo Otávio de AraújoMatis, Georgios K.Costa, Leonardo FerrazKitamura, Matheus Augusto PintoCarvalho Júnior, Eduardo Vieira deBarbosa, Breno José Alencar PiresSantiago, Isaac BispoSilva, Tatiane IndrusiakSilva, Fabiana Queiroga de Paula AraújoPereira, Carlos UmbertoAzevedo Filho, Hildo Rocha Cirne de2017-06-27T22:58:18Z2017-06-27T22:58:18Z2011-10SILVA, D. O. de A. Ocular melanoma: keep your eyes open for late brain metastases. Surgical Neurology International, v. 2, n. 144, out. 2011. Disponível em: <http://surgicalneurologyint.com/surgicalint-articles/ocular-melanoma-keep-your-eyes-open-for-late-brain-metastases/>. Acesso em: 27 jun. 2017.2152-7806https://ri.ufs.br/handle/riufs/2066Creative Commons Attribution-NonCommercial-ShareAlike 4.0 LicenseBackground:The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. Case Description:The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. Conclusion:The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed.Medknow PublicationsMetástaseCérebroCirurgiaBrain metastasisChoroidal melanomaSurgical treatmentOcular melanoma: keep your eyes open for late brain metastasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILOcularMelanoma.pdf.jpgOcularMelanoma.pdf.jpgGenerated Thumbnailimage/jpeg1739https://ri.ufs.br/jspui/bitstream/riufs/2066/4/OcularMelanoma.pdf.jpg1508b66ed9e74e228e9e9b74fa90cf94MD54ORIGINALOcularMelanoma.pdfOcularMelanoma.pdfapplication/pdf1254078https://ri.ufs.br/jspui/bitstream/riufs/2066/1/OcularMelanoma.pdf559ef7c5f9e2703fe121a1ee62ed0a63MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/2066/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTOcularMelanoma.pdf.txtOcularMelanoma.pdf.txtExtracted texttext/plain15471https://ri.ufs.br/jspui/bitstream/riufs/2066/3/OcularMelanoma.pdf.txt1fb864f78e41c99b852e76e4c16b0513MD53riufs/20662017-06-28 02:00:32.413oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-06-28T05:00:32Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.pt_BR.fl_str_mv |
Ocular melanoma: keep your eyes open for late brain metastases |
title |
Ocular melanoma: keep your eyes open for late brain metastases |
spellingShingle |
Ocular melanoma: keep your eyes open for late brain metastases Silva, Danilo Otávio de Araújo Metástase Cérebro Cirurgia Brain metastasis Choroidal melanoma Surgical treatment |
title_short |
Ocular melanoma: keep your eyes open for late brain metastases |
title_full |
Ocular melanoma: keep your eyes open for late brain metastases |
title_fullStr |
Ocular melanoma: keep your eyes open for late brain metastases |
title_full_unstemmed |
Ocular melanoma: keep your eyes open for late brain metastases |
title_sort |
Ocular melanoma: keep your eyes open for late brain metastases |
author |
Silva, Danilo Otávio de Araújo |
author_facet |
Silva, Danilo Otávio de Araújo Matis, Georgios K. Costa, Leonardo Ferraz Kitamura, Matheus Augusto Pinto Carvalho Júnior, Eduardo Vieira de Barbosa, Breno José Alencar Pires Santiago, Isaac Bispo Silva, Tatiane Indrusiak Silva, Fabiana Queiroga de Paula Araújo Pereira, Carlos Umberto Azevedo Filho, Hildo Rocha Cirne de |
author_role |
author |
author2 |
Matis, Georgios K. Costa, Leonardo Ferraz Kitamura, Matheus Augusto Pinto Carvalho Júnior, Eduardo Vieira de Barbosa, Breno José Alencar Pires Santiago, Isaac Bispo Silva, Tatiane Indrusiak Silva, Fabiana Queiroga de Paula Araújo Pereira, Carlos Umberto Azevedo Filho, Hildo Rocha Cirne de |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Silva, Danilo Otávio de Araújo Matis, Georgios K. Costa, Leonardo Ferraz Kitamura, Matheus Augusto Pinto Carvalho Júnior, Eduardo Vieira de Barbosa, Breno José Alencar Pires Santiago, Isaac Bispo Silva, Tatiane Indrusiak Silva, Fabiana Queiroga de Paula Araújo Pereira, Carlos Umberto Azevedo Filho, Hildo Rocha Cirne de |
dc.subject.por.fl_str_mv |
Metástase Cérebro Cirurgia Brain metastasis Choroidal melanoma Surgical treatment |
topic |
Metástase Cérebro Cirurgia Brain metastasis Choroidal melanoma Surgical treatment |
description |
Background:The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. Case Description:The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. Conclusion:The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed. |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011-10 |
dc.date.accessioned.fl_str_mv |
2017-06-27T22:58:18Z |
dc.date.available.fl_str_mv |
2017-06-27T22:58:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SILVA, D. O. de A. Ocular melanoma: keep your eyes open for late brain metastases. Surgical Neurology International, v. 2, n. 144, out. 2011. Disponível em: <http://surgicalneurologyint.com/surgicalint-articles/ocular-melanoma-keep-your-eyes-open-for-late-brain-metastases/>. Acesso em: 27 jun. 2017. |
dc.identifier.uri.fl_str_mv |
https://ri.ufs.br/handle/riufs/2066 |
dc.identifier.issn.none.fl_str_mv |
2152-7806 |
dc.identifier.license.pt_BR.fl_str_mv |
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License |
identifier_str_mv |
SILVA, D. O. de A. Ocular melanoma: keep your eyes open for late brain metastases. Surgical Neurology International, v. 2, n. 144, out. 2011. Disponível em: <http://surgicalneurologyint.com/surgicalint-articles/ocular-melanoma-keep-your-eyes-open-for-late-brain-metastases/>. Acesso em: 27 jun. 2017. 2152-7806 Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License |
url |
https://ri.ufs.br/handle/riufs/2066 |
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eng |
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eng |
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openAccess |
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Medknow Publications |
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Medknow Publications |
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Universidade Federal de Sergipe (UFS) |
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