Ocular melanoma: keep your eyes open for late brain metastases

Detalhes bibliográficos
Autor(a) principal: Silva, Danilo Otávio de Araújo
Data de Publicação: 2011
Outros Autores: Matis, Georgios K., Costa, Leonardo Ferraz, Kitamura, Matheus Augusto Pinto, Carvalho Júnior, Eduardo Vieira de, Barbosa, Breno José Alencar Pires, Santiago, Isaac Bispo, Silva, Tatiane Indrusiak, Silva, Fabiana Queiroga de Paula Araújo, Pereira, Carlos Umberto, Azevedo Filho, Hildo Rocha Cirne de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/handle/riufs/2066
Resumo: Background:The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. Case Description:The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. Conclusion:The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed.
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spelling Silva, Danilo Otávio de AraújoMatis, Georgios K.Costa, Leonardo FerrazKitamura, Matheus Augusto PintoCarvalho Júnior, Eduardo Vieira deBarbosa, Breno José Alencar PiresSantiago, Isaac BispoSilva, Tatiane IndrusiakSilva, Fabiana Queiroga de Paula AraújoPereira, Carlos UmbertoAzevedo Filho, Hildo Rocha Cirne de2017-06-27T22:58:18Z2017-06-27T22:58:18Z2011-10SILVA, D. O. de A. Ocular melanoma: keep your eyes open for late brain metastases. Surgical Neurology International, v. 2, n. 144, out. 2011. Disponível em: <http://surgicalneurologyint.com/surgicalint-articles/ocular-melanoma-keep-your-eyes-open-for-late-brain-metastases/>. Acesso em: 27 jun. 2017.2152-7806https://ri.ufs.br/handle/riufs/2066Creative Commons Attribution-NonCommercial-ShareAlike 4.0 LicenseBackground:The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. Case Description:The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. Conclusion:The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed.Medknow PublicationsMetástaseCérebroCirurgiaBrain metastasisChoroidal melanomaSurgical treatmentOcular melanoma: keep your eyes open for late brain metastasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILOcularMelanoma.pdf.jpgOcularMelanoma.pdf.jpgGenerated Thumbnailimage/jpeg1739https://ri.ufs.br/jspui/bitstream/riufs/2066/4/OcularMelanoma.pdf.jpg1508b66ed9e74e228e9e9b74fa90cf94MD54ORIGINALOcularMelanoma.pdfOcularMelanoma.pdfapplication/pdf1254078https://ri.ufs.br/jspui/bitstream/riufs/2066/1/OcularMelanoma.pdf559ef7c5f9e2703fe121a1ee62ed0a63MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/2066/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTOcularMelanoma.pdf.txtOcularMelanoma.pdf.txtExtracted texttext/plain15471https://ri.ufs.br/jspui/bitstream/riufs/2066/3/OcularMelanoma.pdf.txt1fb864f78e41c99b852e76e4c16b0513MD53riufs/20662017-06-28 02:00:32.413oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-06-28T05:00:32Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Ocular melanoma: keep your eyes open for late brain metastases
title Ocular melanoma: keep your eyes open for late brain metastases
spellingShingle Ocular melanoma: keep your eyes open for late brain metastases
Silva, Danilo Otávio de Araújo
Metástase
Cérebro
Cirurgia
Brain metastasis
Choroidal melanoma
Surgical treatment
title_short Ocular melanoma: keep your eyes open for late brain metastases
title_full Ocular melanoma: keep your eyes open for late brain metastases
title_fullStr Ocular melanoma: keep your eyes open for late brain metastases
title_full_unstemmed Ocular melanoma: keep your eyes open for late brain metastases
title_sort Ocular melanoma: keep your eyes open for late brain metastases
author Silva, Danilo Otávio de Araújo
author_facet Silva, Danilo Otávio de Araújo
Matis, Georgios K.
Costa, Leonardo Ferraz
Kitamura, Matheus Augusto Pinto
Carvalho Júnior, Eduardo Vieira de
Barbosa, Breno José Alencar Pires
Santiago, Isaac Bispo
Silva, Tatiane Indrusiak
Silva, Fabiana Queiroga de Paula Araújo
Pereira, Carlos Umberto
Azevedo Filho, Hildo Rocha Cirne de
author_role author
author2 Matis, Georgios K.
Costa, Leonardo Ferraz
Kitamura, Matheus Augusto Pinto
Carvalho Júnior, Eduardo Vieira de
Barbosa, Breno José Alencar Pires
Santiago, Isaac Bispo
Silva, Tatiane Indrusiak
Silva, Fabiana Queiroga de Paula Araújo
Pereira, Carlos Umberto
Azevedo Filho, Hildo Rocha Cirne de
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Danilo Otávio de Araújo
Matis, Georgios K.
Costa, Leonardo Ferraz
Kitamura, Matheus Augusto Pinto
Carvalho Júnior, Eduardo Vieira de
Barbosa, Breno José Alencar Pires
Santiago, Isaac Bispo
Silva, Tatiane Indrusiak
Silva, Fabiana Queiroga de Paula Araújo
Pereira, Carlos Umberto
Azevedo Filho, Hildo Rocha Cirne de
dc.subject.por.fl_str_mv Metástase
Cérebro
Cirurgia
Brain metastasis
Choroidal melanoma
Surgical treatment
topic Metástase
Cérebro
Cirurgia
Brain metastasis
Choroidal melanoma
Surgical treatment
description Background:The most frequent intraocular malignant tumor is choroidal melanoma (CM). Although brain metastasis is a common feature of other types of cancers, metastasis of CM to the brain is a rare entity. Case Description:The authors report a case of a 28-year-old woman presenting with a single brain metastasis, 10 years after the treatment of a CM. She underwent a total en-bloc resection of the lesion, and the diagnosis was confirmed histopathologically. The patient concomitantly received whole-brain irradiation therapy combined with chemotherapy, with a survival period of 24 months. Conclusion:The present case report draws attention to the necessity of a close and lifelong follow-up of patients treated for this malignancy. The international literature is also reviewed.
publishDate 2011
dc.date.issued.fl_str_mv 2011-10
dc.date.accessioned.fl_str_mv 2017-06-27T22:58:18Z
dc.date.available.fl_str_mv 2017-06-27T22:58:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, D. O. de A. Ocular melanoma: keep your eyes open for late brain metastases. Surgical Neurology International, v. 2, n. 144, out. 2011. Disponível em: <http://surgicalneurologyint.com/surgicalint-articles/ocular-melanoma-keep-your-eyes-open-for-late-brain-metastases/>. Acesso em: 27 jun. 2017.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/handle/riufs/2066
dc.identifier.issn.none.fl_str_mv 2152-7806
dc.identifier.license.pt_BR.fl_str_mv Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License
identifier_str_mv SILVA, D. O. de A. Ocular melanoma: keep your eyes open for late brain metastases. Surgical Neurology International, v. 2, n. 144, out. 2011. Disponível em: <http://surgicalneurologyint.com/surgicalint-articles/ocular-melanoma-keep-your-eyes-open-for-late-brain-metastases/>. Acesso em: 27 jun. 2017.
2152-7806
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License
url https://ri.ufs.br/handle/riufs/2066
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Medknow Publications
publisher.none.fl_str_mv Medknow Publications
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reponame_str Repositório Institucional da UFS
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