Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado

Detalhes bibliográficos
Autor(a) principal: Araújo, Fernanda Mendonça
Data de Publicação: 2015
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/handle/riufs/3978
Resumo: Fibromyalgia (FM) is a syndrome characterized by chronic widespread musculoskeletal pain and hyperalgesia, especially in specific points called |tender points|. Furthermore, this syndrome is associated with psychosomatic disorders, such as chronic fatigue, depression, anxiety and sleep disorders. Interferential current (IFC) is a non-pharmacological and non-invasive treatment commonly used in promoting the symptomatic relief of pain. However, there is little evidence to support the effective use of IFC in patients with FM and little is known about the optimal parameters of stimulation by IFC. Thus, the present study had, as objective, to investigate the effects of different intensities of stimulation with IFC in pain relief and the other disorders present in individuals with FM. This study is a randomized, placebo-controlled and double-blind clinical trial. To assess the effects of IFC before and after treatment, the following outcomes were measured (with their respective instruments) in each session of application by IFC: pressure pain threshold (PPT: digital algometry), cutaneous sensory threshold (CST: von Frey filaments) and pain intensity at rest (11-point numeric rating scale). In addition, were also measured in the first and last day of treatment: impact of fibromyalgia (Fibromyalgia Impact Questionnaire), depression level (Beck Depression Inventory), anxiety (State-Trait Anxiety Inventory), functional capacity (Sitting-Rising and Timed Up and Go tests), fear to move (Tampa Scale of Kinesiophobia), pain catastrophizing (Pain Catastrophizing Scale), characterization of pain (McGill Pain Questionnaire), quality of life (Short Form Health Survey 36), temporal summation (temporal summation test), conditioned pain modulation (conditioned pain modulation test) and fatigue intensity (11-point numeric rating scale). Twenty nine women with FM were recruited and allocated to three groups: Motor (n=10; IFC was applied at high intensity, with motor contraction), Sensory (n=10; high intensity, but without motor contraction) and placebo (n=9). Patients allocated into the motor and sensory groups were stimulated at an amplitude-modulated frequency of 100 Hz, for 30 minutes. In the placebo group, the current was released only in the first 40 seconds of stimulation. Ten treatment sessions were performed and the electrodes were applied to the paravertebral region. The t Student test, Wilcoxon and ANOVA for repeated measures were used to compare the results found, intra-group, before and after treatment. In women allocated to the motor group, there was a significant increase PPT, measured in the conditioned pain modulation test (p≤0.03), and significant reduction in amplification of pain intensity in temporal summation (p=0.03) after the end of treatment. None of the studied group showed significant change in the PPT and CST values in 18 tender points specific to FM, and pain intensity each treatment session with IFC (p>0.05). However, only the motor group had a significant reduction in the impact of the disease (p=0.01), depression (p=0.006), anxiety state (p=0.01), kinesiophobia (p=0.002), catastrophizing (p=0.008), pain rating index (p=0.04), fatigue (p=0.02) and number of tender points (p=0.04), and increased quality of life (p=0.006). Thus, the results, obtained in this study, provide strong evidence that the IFC, only when applied in high intensities of stimulation, is an effective treatment in reducing pain and psychosomatic disorders present in patients with FM
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spelling Araújo, Fernanda Mendonçahttp://lattes.cnpq.br/9819654988177433Santana, Josimari Melo dehttp://lattes.cnpq.br/19872562809838482017-09-26T12:31:16Z2017-09-26T12:31:16Z2015-02-27ARAÚJO, Fernanda Mendonça. Effect of interferential current on fibromyalgia : randomized clinical trial. 2015. 98 f. Dissertação (Mestrado em Ciências Fisiológicas) - Universidade Federal de Sergipe, São Cristóvão, 2015.https://ri.ufs.br/handle/riufs/3978Fibromyalgia (FM) is a syndrome characterized by chronic widespread musculoskeletal pain and hyperalgesia, especially in specific points called |tender points|. Furthermore, this syndrome is associated with psychosomatic disorders, such as chronic fatigue, depression, anxiety and sleep disorders. Interferential current (IFC) is a non-pharmacological and non-invasive treatment commonly used in promoting the symptomatic relief of pain. However, there is little evidence to support the effective use of IFC in patients with FM and little is known about the optimal parameters of stimulation by IFC. Thus, the present study had, as objective, to investigate the effects of different intensities of stimulation with IFC in pain relief and the other disorders present in individuals with FM. This study is a randomized, placebo-controlled and double-blind clinical trial. To assess the effects of IFC before and after treatment, the following outcomes were measured (with their respective instruments) in each session of application by IFC: pressure pain threshold (PPT: digital algometry), cutaneous sensory threshold (CST: von Frey filaments) and pain intensity at rest (11-point numeric rating scale). In addition, were also measured in the first and last day of treatment: impact of fibromyalgia (Fibromyalgia Impact Questionnaire), depression level (Beck Depression Inventory), anxiety (State-Trait Anxiety Inventory), functional capacity (Sitting-Rising and Timed Up and Go tests), fear to move (Tampa Scale of Kinesiophobia), pain catastrophizing (Pain Catastrophizing Scale), characterization of pain (McGill Pain Questionnaire), quality of life (Short Form Health Survey 36), temporal summation (temporal summation test), conditioned pain modulation (conditioned pain modulation test) and fatigue intensity (11-point numeric rating scale). Twenty nine women with FM were recruited and allocated to three groups: Motor (n=10; IFC was applied at high intensity, with motor contraction), Sensory (n=10; high intensity, but without motor contraction) and placebo (n=9). Patients allocated into the motor and sensory groups were stimulated at an amplitude-modulated frequency of 100 Hz, for 30 minutes. In the placebo group, the current was released only in the first 40 seconds of stimulation. Ten treatment sessions were performed and the electrodes were applied to the paravertebral region. The t Student test, Wilcoxon and ANOVA for repeated measures were used to compare the results found, intra-group, before and after treatment. In women allocated to the motor group, there was a significant increase PPT, measured in the conditioned pain modulation test (p≤0.03), and significant reduction in amplification of pain intensity in temporal summation (p=0.03) after the end of treatment. None of the studied group showed significant change in the PPT and CST values in 18 tender points specific to FM, and pain intensity each treatment session with IFC (p>0.05). However, only the motor group had a significant reduction in the impact of the disease (p=0.01), depression (p=0.006), anxiety state (p=0.01), kinesiophobia (p=0.002), catastrophizing (p=0.008), pain rating index (p=0.04), fatigue (p=0.02) and number of tender points (p=0.04), and increased quality of life (p=0.006). Thus, the results, obtained in this study, provide strong evidence that the IFC, only when applied in high intensities of stimulation, is an effective treatment in reducing pain and psychosomatic disorders present in patients with FMA fibromialgia (FM) é uma síndrome caracterizada por dor musculoesquelética crônica generalizada e hiperalgesia, principalmente em pontos específicos, chamados tender points . Além disso, essa síndrome está associada a alterações psicossomáticas, como fadiga crônica, depressão, ansiedade e distúrbios do sono. A corrente interferencial (CI) é um tratamento não-farmacológico e não-invasivo comumente utilizado na promoção do alívio sintomático da dor. Apesar disso, há pouca evidência que suporte o uso efetivo da CI em pacientes com FM e pouco se conhece sobre os parâmetros ideais de estimulação por meio da CI. Sendo assim, o presente estudo teve, como objetivo, investigar os efeitos de diferentes intensidades de estimulação com CI no alívio da dor, bem como das demais alterações presentes em indivíduos com FM. Este trabalho trata-se de um ensaio clínico randomizado, controlado por placebo e duplamente encoberto. Para avaliação dos efeitos da CI antes e após o tratamento, foram medidos os seguintes desfechos (com seus respectivos instrumentos) em cada sessão de aplicação da CI: limiar de dor por pressão (LDP: algometria digital), limiar sensitivo cutâneo (LSC: filamentos de von Frey) e intensidade de dor em repouso (Escala Numérica de 11 pontos). Além disso, foram também mensurados, no primeiro e no último dia de atendimento: impacto da fibromialgia (Questionário de Impacto da Fibromialgia), nível de depressão (Inventário de Depressão de Beck), ansiedade (Inventário de Ansiedade Traço-Estado), capacidade funcional (testes de Sentar e Levantar e Timed Up and Go), medo de movimentar-se (Escala de Cinesiofobia de Tampa), catastrofização da dor (Escala de Catastrofização da Dor), caracterização da dor (Questionário de Dor McGill), qualidade de vida (Short Form Health Survey 36), somação temporal (Teste de Somação Temporal), modulação condicionada da dor (Teste de Modulação Condicionada da Dor) e intensidade de fadiga (Escala Numérica de 11 pontos). Foram recrutadas 29 mulheres com FM, que foram alocadas em três grupos de estudo: Motor (n=10; a CI foi aplicada em alta intensidade, com contração motora), Sensorial (n=10; alta intensidade, porém sem contração motora) e Placebo (n=9). As pacientes alocadas nos grupos motor e sensorial foram estimuladas com uma frequência de amplitude modulada em 100 Hz, durante 30 minutos. Já no grupo placebo, a corrente foi liberada apenas nos primeiros 40 segundos de estimulação. Foram realizadas 10 sessões de tratamento e os eletrodos foram aplicados na região paravertebral. Os testes t de Student, Wilcoxon e ANOVA para medidas repetidas foram utilizados para comparação dos resultados encontrados, intra-grupo, antes e após o tratamento. Nas mulheres alocadas no grupo motor, foi observado aumento significativo do LDP, mensurado no teste de modulação condicionada da dor (p≤0,03), além de redução significativa na amplificação da intensidade de dor da somação temporal (p=0,03) após o término do tratamento. Nenhum dos grupos de estudo apresentou alteração significativa dos valores de LDP e LSC nos 18 tender points específicos para FM, e na intensidade de dor a cada sessão de tratamento com CI (p>0,05). No entanto, apenas o grupo motor apresentou redução significativa no impacto da doença (p=0,01), depressão (p=0,006), estado de ansiedade (p=0,01), cinesiofobia (p=0,002), catastrofização (p=0,008), índice de classificação da dor (p=0,04), fadiga (p=0,02) e quantidade de tender points (p=0,04), além do aumento da qualidade de vida (p=0,006). Dessa forma, os resultados encontrados, no presente estudo, fornecem fortes evidências de que a CI, apenas quando aplicada em altas intensidades de estimulação, é um tratamento eficaz na redução da dor e alterações psicossomáticas presentes em indivíduos com FM.Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorapplication/pdfporUniversidade Federal de SergipePós-Graduação em Ciências FisiológicasUFSBRCorrente interferencialFibromialgiaDor crônica generalizadaAnalgesiaTerapia por estimulação elétricaFisiologiaFisiologia humanaEletroterapiaInterferential currentFibromyalgiaChronic widespread painAnalgesiaElectric stimulation therapyCNPQ::CIENCIAS BIOLOGICAS::FISIOLOGIAEfeito da corrente interferencial na fibromialgia : ensaio clínico randomizadoEffect of interferential current on fibromyalgia : randomized clinical trialinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSTEXTFERNANDA_MENDONCA_ARAUJO.pdf.txtFERNANDA_MENDONCA_ARAUJO.pdf.txtExtracted texttext/plain171437https://ri.ufs.br/jspui/bitstream/riufs/3978/2/FERNANDA_MENDONCA_ARAUJO.pdf.txt7c54ad659b43f741de09d927deaaa906MD52THUMBNAILFERNANDA_MENDONCA_ARAUJO.pdf.jpgFERNANDA_MENDONCA_ARAUJO.pdf.jpgGenerated Thumbnailimage/jpeg1243https://ri.ufs.br/jspui/bitstream/riufs/3978/3/FERNANDA_MENDONCA_ARAUJO.pdf.jpg908f4e3b62642bb9caea5f2513511930MD53ORIGINALFERNANDA_MENDONCA_ARAUJO.pdfapplication/pdf1350620https://ri.ufs.br/jspui/bitstream/riufs/3978/1/FERNANDA_MENDONCA_ARAUJO.pdfd038e442e7ff9befe986b78197282a4dMD51riufs/39782017-11-24 21:45:18.394oai:ufs.br:riufs/3978Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-11-25T00:45:18Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.por.fl_str_mv Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado
dc.title.alternative.eng.fl_str_mv Effect of interferential current on fibromyalgia : randomized clinical trial
title Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado
spellingShingle Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado
Araújo, Fernanda Mendonça
Corrente interferencial
Fibromialgia
Dor crônica generalizada
Analgesia
Terapia por estimulação elétrica
Fisiologia
Fisiologia humana
Eletroterapia
Interferential current
Fibromyalgia
Chronic widespread pain
Analgesia
Electric stimulation therapy
CNPQ::CIENCIAS BIOLOGICAS::FISIOLOGIA
title_short Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado
title_full Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado
title_fullStr Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado
title_full_unstemmed Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado
title_sort Efeito da corrente interferencial na fibromialgia : ensaio clínico randomizado
author Araújo, Fernanda Mendonça
author_facet Araújo, Fernanda Mendonça
author_role author
dc.contributor.author.fl_str_mv Araújo, Fernanda Mendonça
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9819654988177433
dc.contributor.advisor1.fl_str_mv Santana, Josimari Melo de
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/1987256280983848
contributor_str_mv Santana, Josimari Melo de
dc.subject.por.fl_str_mv Corrente interferencial
Fibromialgia
Dor crônica generalizada
Analgesia
Terapia por estimulação elétrica
Fisiologia
Fisiologia humana
Eletroterapia
topic Corrente interferencial
Fibromialgia
Dor crônica generalizada
Analgesia
Terapia por estimulação elétrica
Fisiologia
Fisiologia humana
Eletroterapia
Interferential current
Fibromyalgia
Chronic widespread pain
Analgesia
Electric stimulation therapy
CNPQ::CIENCIAS BIOLOGICAS::FISIOLOGIA
dc.subject.eng.fl_str_mv Interferential current
Fibromyalgia
Chronic widespread pain
Analgesia
Electric stimulation therapy
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS BIOLOGICAS::FISIOLOGIA
description Fibromyalgia (FM) is a syndrome characterized by chronic widespread musculoskeletal pain and hyperalgesia, especially in specific points called |tender points|. Furthermore, this syndrome is associated with psychosomatic disorders, such as chronic fatigue, depression, anxiety and sleep disorders. Interferential current (IFC) is a non-pharmacological and non-invasive treatment commonly used in promoting the symptomatic relief of pain. However, there is little evidence to support the effective use of IFC in patients with FM and little is known about the optimal parameters of stimulation by IFC. Thus, the present study had, as objective, to investigate the effects of different intensities of stimulation with IFC in pain relief and the other disorders present in individuals with FM. This study is a randomized, placebo-controlled and double-blind clinical trial. To assess the effects of IFC before and after treatment, the following outcomes were measured (with their respective instruments) in each session of application by IFC: pressure pain threshold (PPT: digital algometry), cutaneous sensory threshold (CST: von Frey filaments) and pain intensity at rest (11-point numeric rating scale). In addition, were also measured in the first and last day of treatment: impact of fibromyalgia (Fibromyalgia Impact Questionnaire), depression level (Beck Depression Inventory), anxiety (State-Trait Anxiety Inventory), functional capacity (Sitting-Rising and Timed Up and Go tests), fear to move (Tampa Scale of Kinesiophobia), pain catastrophizing (Pain Catastrophizing Scale), characterization of pain (McGill Pain Questionnaire), quality of life (Short Form Health Survey 36), temporal summation (temporal summation test), conditioned pain modulation (conditioned pain modulation test) and fatigue intensity (11-point numeric rating scale). Twenty nine women with FM were recruited and allocated to three groups: Motor (n=10; IFC was applied at high intensity, with motor contraction), Sensory (n=10; high intensity, but without motor contraction) and placebo (n=9). Patients allocated into the motor and sensory groups were stimulated at an amplitude-modulated frequency of 100 Hz, for 30 minutes. In the placebo group, the current was released only in the first 40 seconds of stimulation. Ten treatment sessions were performed and the electrodes were applied to the paravertebral region. The t Student test, Wilcoxon and ANOVA for repeated measures were used to compare the results found, intra-group, before and after treatment. In women allocated to the motor group, there was a significant increase PPT, measured in the conditioned pain modulation test (p≤0.03), and significant reduction in amplification of pain intensity in temporal summation (p=0.03) after the end of treatment. None of the studied group showed significant change in the PPT and CST values in 18 tender points specific to FM, and pain intensity each treatment session with IFC (p>0.05). However, only the motor group had a significant reduction in the impact of the disease (p=0.01), depression (p=0.006), anxiety state (p=0.01), kinesiophobia (p=0.002), catastrophizing (p=0.008), pain rating index (p=0.04), fatigue (p=0.02) and number of tender points (p=0.04), and increased quality of life (p=0.006). Thus, the results, obtained in this study, provide strong evidence that the IFC, only when applied in high intensities of stimulation, is an effective treatment in reducing pain and psychosomatic disorders present in patients with FM
publishDate 2015
dc.date.issued.fl_str_mv 2015-02-27
dc.date.accessioned.fl_str_mv 2017-09-26T12:31:16Z
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dc.identifier.citation.fl_str_mv ARAÚJO, Fernanda Mendonça. Effect of interferential current on fibromyalgia : randomized clinical trial. 2015. 98 f. Dissertação (Mestrado em Ciências Fisiológicas) - Universidade Federal de Sergipe, São Cristóvão, 2015.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/handle/riufs/3978
identifier_str_mv ARAÚJO, Fernanda Mendonça. Effect of interferential current on fibromyalgia : randomized clinical trial. 2015. 98 f. Dissertação (Mestrado em Ciências Fisiológicas) - Universidade Federal de Sergipe, São Cristóvão, 2015.
url https://ri.ufs.br/handle/riufs/3978
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