Experimental model of a bone gap by radial ostectomy in rabbits
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Biotemas (Online) |
Texto Completo: | https://periodicos.ufsc.br/index.php/biotemas/article/view/2175-7925.2010v23n3p149 |
Resumo: | A lot of experimental models have been used to study the process of a fracture's consolidation, but the problem is that due to anatomic, biologic and technical differences, these models do not always have appropriate parameters for the exact species, for which the experiment was done. The rabbit is an experimental model that is widely used in studies involving bone physiopatology in the face of fractures and their different types of treatment, corresponding to approximately 35% of all the musculoskeletic system's scientific studies. Several surgical techniques have been used on rabbit's bone for experimental studies, and the partial ostectomy of the radius bone is one of them. In this study, 14 rabbits (Oryctolagus cuniculus familiaris), males, adults, of white New Zeland breed, neutered, with weight between three and four kilograms, were used. Clinically, the animals did not present any alterations that compromised the study. There were evaluated through radiographic exam on days zero, 30 and 60 after the surgery, visualizing the quality of the gap and the relevant alteration of bone proliferation. The histologic exam elucidated the neoformed bone architecture and its components. The efficacy of the techinique was proved and it could be reproduced for many purposes in orthopedic surgery. |
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Experimental model of a bone gap by radial ostectomy in rabbitsModelo experimental de falha óssea por meio de ostectomia do rádio em coelhosA lot of experimental models have been used to study the process of a fracture's consolidation, but the problem is that due to anatomic, biologic and technical differences, these models do not always have appropriate parameters for the exact species, for which the experiment was done. The rabbit is an experimental model that is widely used in studies involving bone physiopatology in the face of fractures and their different types of treatment, corresponding to approximately 35% of all the musculoskeletic system's scientific studies. Several surgical techniques have been used on rabbit's bone for experimental studies, and the partial ostectomy of the radius bone is one of them. In this study, 14 rabbits (Oryctolagus cuniculus familiaris), males, adults, of white New Zeland breed, neutered, with weight between three and four kilograms, were used. Clinically, the animals did not present any alterations that compromised the study. There were evaluated through radiographic exam on days zero, 30 and 60 after the surgery, visualizing the quality of the gap and the relevant alteration of bone proliferation. The histologic exam elucidated the neoformed bone architecture and its components. The efficacy of the techinique was proved and it could be reproduced for many purposes in orthopedic surgery.Muitos modelos experimentais são utilizados para estudar o processo de consolidação de fraturas, no entanto, devido às diferenças anatômicas, biológicas e técnicas, nem sempre tais modelos possuem parâmetros adequados para a espécie de interesse final, para qual se realiza o experimento. O coelho é um modelo experimental muito utilizado nos estudos que envolvem a fisiopatologia óssea frente às fraturas e seus diferentes tipos de tratamento, correspondendo à aproximadamente 35% de todos os estudos científicos do sistema músculo-esquelético. Diversas técnicas cirúrgicas já foram utilizadas em ossos de coelhos para estudos experimentais, e a ostectomia parcial do rádio é uma delas. Neste estudo, foram utilizados 14 coelhos (Oryctolagus cuniculus familiaris), machos, adultos jovens, da raça Nova Zelândia branca, não castrados, com peso corpóreo variando entre três a quatro quilos. Clinicamente os animais não apresentaram alterações que comprometessem o estudo. Os mesmos foram avaliados por meio de exame radiográfico nos dias zero, 30 e 60 após o procedimento cirúrgico nos quais foram visibilizadas a qualidade da falha cirúrgica e as alterações pertinentes à proliferação óssea. O exame histológico permitiu verificar a arquitetura óssea neoformada e seus componentes. A eficácia da técnica foi comprovada, podendo ser reproduzida para diversos fins dentro da cirurgia ortopédica.Universidade Federal de Santa Catarina2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.ufsc.br/index.php/biotemas/article/view/2175-7925.2010v23n3p14910.5007/2175-7925.2010v23n3p149Biotemas; v. 23 n. 3 (2010); 149-1572175-79250103-1643reponame:Biotemas (Online)instname:Universidade Federal de Santa Catarina (UFSC)instacron:UFSCporhttps://periodicos.ufsc.br/index.php/biotemas/article/view/2175-7925.2010v23n3p149/14486Copyright (c) 2010 Antonio Carlos Cunha Lacreta Junior, Everton Regonato, Lucas Bahdour Cossi, Ciro Alexandre Teixeira Cruvinel, Júlio Carlos Canolainfo:eu-repo/semantics/openAccessLacreta Junior, Antonio Carlos CunhaRegonato, EvertonCossi, Lucas BahdourCruvinel, Ciro Alexandre TeixeiraCanola, Júlio Carlos2017-11-13T16:44:13Zoai:periodicos.ufsc.br:article/15987Revistahttp://www.biotemas.ufsc.br/index.htmPUBhttps://periodicos.ufsc.br/index.php/biotemas/oai||carlospinto@ccb.ufsc.br2175-79250103-1643opendoar:2017-11-13T16:44:13Biotemas (Online) - Universidade Federal de Santa Catarina (UFSC)false |
dc.title.none.fl_str_mv |
Experimental model of a bone gap by radial ostectomy in rabbits Modelo experimental de falha óssea por meio de ostectomia do rádio em coelhos |
title |
Experimental model of a bone gap by radial ostectomy in rabbits |
spellingShingle |
Experimental model of a bone gap by radial ostectomy in rabbits Lacreta Junior, Antonio Carlos Cunha |
title_short |
Experimental model of a bone gap by radial ostectomy in rabbits |
title_full |
Experimental model of a bone gap by radial ostectomy in rabbits |
title_fullStr |
Experimental model of a bone gap by radial ostectomy in rabbits |
title_full_unstemmed |
Experimental model of a bone gap by radial ostectomy in rabbits |
title_sort |
Experimental model of a bone gap by radial ostectomy in rabbits |
author |
Lacreta Junior, Antonio Carlos Cunha |
author_facet |
Lacreta Junior, Antonio Carlos Cunha Regonato, Everton Cossi, Lucas Bahdour Cruvinel, Ciro Alexandre Teixeira Canola, Júlio Carlos |
author_role |
author |
author2 |
Regonato, Everton Cossi, Lucas Bahdour Cruvinel, Ciro Alexandre Teixeira Canola, Júlio Carlos |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Lacreta Junior, Antonio Carlos Cunha Regonato, Everton Cossi, Lucas Bahdour Cruvinel, Ciro Alexandre Teixeira Canola, Júlio Carlos |
description |
A lot of experimental models have been used to study the process of a fracture's consolidation, but the problem is that due to anatomic, biologic and technical differences, these models do not always have appropriate parameters for the exact species, for which the experiment was done. The rabbit is an experimental model that is widely used in studies involving bone physiopatology in the face of fractures and their different types of treatment, corresponding to approximately 35% of all the musculoskeletic system's scientific studies. Several surgical techniques have been used on rabbit's bone for experimental studies, and the partial ostectomy of the radius bone is one of them. In this study, 14 rabbits (Oryctolagus cuniculus familiaris), males, adults, of white New Zeland breed, neutered, with weight between three and four kilograms, were used. Clinically, the animals did not present any alterations that compromised the study. There were evaluated through radiographic exam on days zero, 30 and 60 after the surgery, visualizing the quality of the gap and the relevant alteration of bone proliferation. The histologic exam elucidated the neoformed bone architecture and its components. The efficacy of the techinique was proved and it could be reproduced for many purposes in orthopedic surgery. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufsc.br/index.php/biotemas/article/view/2175-7925.2010v23n3p149 10.5007/2175-7925.2010v23n3p149 |
url |
https://periodicos.ufsc.br/index.php/biotemas/article/view/2175-7925.2010v23n3p149 |
identifier_str_mv |
10.5007/2175-7925.2010v23n3p149 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.ufsc.br/index.php/biotemas/article/view/2175-7925.2010v23n3p149/14486 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Catarina |
publisher.none.fl_str_mv |
Universidade Federal de Santa Catarina |
dc.source.none.fl_str_mv |
Biotemas; v. 23 n. 3 (2010); 149-157 2175-7925 0103-1643 reponame:Biotemas (Online) instname:Universidade Federal de Santa Catarina (UFSC) instacron:UFSC |
instname_str |
Universidade Federal de Santa Catarina (UFSC) |
instacron_str |
UFSC |
institution |
UFSC |
reponame_str |
Biotemas (Online) |
collection |
Biotemas (Online) |
repository.name.fl_str_mv |
Biotemas (Online) - Universidade Federal de Santa Catarina (UFSC) |
repository.mail.fl_str_mv |
||carlospinto@ccb.ufsc.br |
_version_ |
1799940548575887360 |