Protein S100B and physical exercise
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
Texto Completo: | https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2010v12n1p77 |
Resumo: | Protein S100B has been used as a peripheral biochemical marker of brain injury and/or activity. However, recent studies have demonstrated that this protein is also increased in serum after physical exercise, although the interpretation of this finding remains controversial. Although predominantly released by astrocytes in the central nervous system, extracerebral sources of protein S100B have been suggested to contribute to the increase in serum levels of this protein. However, in the case of exercises that have an impact on the brain such as boxing, elevated levels are clearly associated with brain damage. More recently, some studies have proposed that protein S100B might be released by activated adipocytes and by damaged muscle cells. If confirmed experimentally, protein S100B might be potentially useful in sports training. We are currently investigating the potential role of serum protein S100B as an indicator of muscle damage. Therefore, the objective of this review was to discuss the current knowledge about the relationship between physical exercise and serum protein S100B and its possible leakage from muscle cells injured by exercise. |
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Protein S100B and physical exerciseA Proteína S100B e o exercício físicoProtein S100B has been used as a peripheral biochemical marker of brain injury and/or activity. However, recent studies have demonstrated that this protein is also increased in serum after physical exercise, although the interpretation of this finding remains controversial. Although predominantly released by astrocytes in the central nervous system, extracerebral sources of protein S100B have been suggested to contribute to the increase in serum levels of this protein. However, in the case of exercises that have an impact on the brain such as boxing, elevated levels are clearly associated with brain damage. More recently, some studies have proposed that protein S100B might be released by activated adipocytes and by damaged muscle cells. If confirmed experimentally, protein S100B might be potentially useful in sports training. We are currently investigating the potential role of serum protein S100B as an indicator of muscle damage. Therefore, the objective of this review was to discuss the current knowledge about the relationship between physical exercise and serum protein S100B and its possible leakage from muscle cells injured by exercise.A proteína S100B cerebral tem sido utilizada como um marcador periférico de injúrias do sistema nervoso central (SNC). Entretanto, estudos recentes demonstraram que a S100B também aumenta após o exercício físico, embora o significado desse aumento ainda não esteja bem claro. Apesar de ser liberada, principalmente, por astrócitos, no sistema nervoso central, fontes de produção extracerebral de S100B durante o exercício podem estar implicadas no aumento sérico desta proteína. No entanto, exercícios que implicam impacto ao cérebro como o boxe, por exemplo, o aumento é claramente associado à lesão cerebral. Assim, trabalhos propõem que o aumento da S100B após o exercício estaria relacionado à secreção ativa por adipócitos e músculos lesados. Uma vez que a liberação da S100B pelo músculo lesado seja confirmada experimentalmente, o uso desta proteína poderia ser aprofundado, principalmente, no treinamento esportivo. Atualmente, estamos desenvolvendo protocolos na direção de avaliar o potencial valor da S100B como indicador de lesão do músculo esquelético. Portanto, o objetivo da presente revisão é apresentar o atual estado de conhecimento sobre a relação entre a proteína S100B e o exercício físico, discutindo os possíveis mecanismos envolvidos e propondo novas abordagens.Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil2010-12-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion"Avaliado por Pares","Artigo Solicitado""Avaliado por Pares", "Artigo Solicitado"Bibliográficaapplication/pdfapplication/pdfhttps://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2010v12n1p7710.1590/1980-0037.2010v12n1p77Brazilian Journal of Kinanthropometry and Human Performance; Vol. 12 No. 1 (2010); 77-81Revista Brasileira de Cineantropometria e Desempenho Humano; v. 12 n. 1 (2010); 77-811980-00371415-8426reponame:Revista Brasileira de Cineantropometria & Desempenho Humano (Online)instname:Universidade Federal de Santa Catarina (UFSC)instacron:UFSCporhttps://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2010v12n1p77/11481https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2010v12n1p77/16455Stocchero, Cintia AlvimMuller, Alexandre PastorisOliveira, Álvaro ReischakPortela, Luis Valmorinfo:eu-repo/semantics/openAccess2018-11-14T09:30:16Zoai:periodicos.ufsc.br:article/6519Revistahttps://periodicos.ufsc.br/index.php/rbcdh/PUBhttps://periodicos.ufsc.br/index.php/rbcdh/oairbcdh@contato.ufsc.br || portaldeperiodicos.bu@contato.ufsc.br1980-00371415-8426opendoar:2018-11-14T09:30:16Revista Brasileira de Cineantropometria & Desempenho Humano (Online) - Universidade Federal de Santa Catarina (UFSC)false |
dc.title.none.fl_str_mv |
Protein S100B and physical exercise A Proteína S100B e o exercício físico |
title |
Protein S100B and physical exercise |
spellingShingle |
Protein S100B and physical exercise Stocchero, Cintia Alvim |
title_short |
Protein S100B and physical exercise |
title_full |
Protein S100B and physical exercise |
title_fullStr |
Protein S100B and physical exercise |
title_full_unstemmed |
Protein S100B and physical exercise |
title_sort |
Protein S100B and physical exercise |
author |
Stocchero, Cintia Alvim |
author_facet |
Stocchero, Cintia Alvim Muller, Alexandre Pastoris Oliveira, Álvaro Reischak Portela, Luis Valmor |
author_role |
author |
author2 |
Muller, Alexandre Pastoris Oliveira, Álvaro Reischak Portela, Luis Valmor |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Stocchero, Cintia Alvim Muller, Alexandre Pastoris Oliveira, Álvaro Reischak Portela, Luis Valmor |
description |
Protein S100B has been used as a peripheral biochemical marker of brain injury and/or activity. However, recent studies have demonstrated that this protein is also increased in serum after physical exercise, although the interpretation of this finding remains controversial. Although predominantly released by astrocytes in the central nervous system, extracerebral sources of protein S100B have been suggested to contribute to the increase in serum levels of this protein. However, in the case of exercises that have an impact on the brain such as boxing, elevated levels are clearly associated with brain damage. More recently, some studies have proposed that protein S100B might be released by activated adipocytes and by damaged muscle cells. If confirmed experimentally, protein S100B might be potentially useful in sports training. We are currently investigating the potential role of serum protein S100B as an indicator of muscle damage. Therefore, the objective of this review was to discuss the current knowledge about the relationship between physical exercise and serum protein S100B and its possible leakage from muscle cells injured by exercise. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-12-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion "Avaliado por Pares","Artigo Solicitado" "Avaliado por Pares", "Artigo Solicitado" Bibliográfica |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2010v12n1p77 10.1590/1980-0037.2010v12n1p77 |
url |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2010v12n1p77 |
identifier_str_mv |
10.1590/1980-0037.2010v12n1p77 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2010v12n1p77/11481 https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2010v12n1p77/16455 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil |
publisher.none.fl_str_mv |
Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil |
dc.source.none.fl_str_mv |
Brazilian Journal of Kinanthropometry and Human Performance; Vol. 12 No. 1 (2010); 77-81 Revista Brasileira de Cineantropometria e Desempenho Humano; v. 12 n. 1 (2010); 77-81 1980-0037 1415-8426 reponame:Revista Brasileira de Cineantropometria & Desempenho Humano (Online) instname:Universidade Federal de Santa Catarina (UFSC) instacron:UFSC |
instname_str |
Universidade Federal de Santa Catarina (UFSC) |
instacron_str |
UFSC |
institution |
UFSC |
reponame_str |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
collection |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) - Universidade Federal de Santa Catarina (UFSC) |
repository.mail.fl_str_mv |
rbcdh@contato.ufsc.br || portaldeperiodicos.bu@contato.ufsc.br |
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1789435121306173440 |