In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs

Detalhes bibliográficos
Autor(a) principal: Boligon, Aline Augusti
Data de Publicação: 2009
Outros Autores: Magoga, Bruna Ribeiro, Feltrin, Andrieli Cassel, Janovik, Vanessa, Athayde, Margareth Linde
Tipo de documento: Artigo
Idioma: por
Título da fonte: Saúde (Santa Maria)
Texto Completo: https://periodicos.ufsm.br/revistasaude/article/view/6527
Resumo: This work describes the antioxidant evaluation through the DPPH free radical methodology, the determination of polyphenol dosage by the method of Folin-Ciocalteau and the content of flavonoids in crude extract and fractions of the Scutia buxifolia twigs (coronilha). The content of flavonoids and polyphenols ranged from 102.02 ± 0.71 to 318.82 ± 1.62 milligram of pirogallic acid per gram of dry plant and 83.47 ± 0.93 to 140.71 ± 2.14 milligram of rutin per gram of dry plant, respectively. The IC50 required concentration to inhibit the activity of DPPH at 50% was: crude extract > CH2Cl2 > AcOEt > n-BuOH. In this study it was established a high positive correlation between fractions of phenolic compounds and antioxidant activity of these (0.99). These results indicate that S. buxifolia has chemicals that are able to catch free radicals, promising compounds in the search for antioxidant drugs against diseases from oxidative stress, being the n-BuOH and AcOEt fractions the most effective ones.
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spelling In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigsPotencial antioxidante in vitro, conteúdo de fenóis e flavonóides nos ramos de Scutia buxifolia ReissekScutia buxifoliaCoronilhaDPPHFree radicals.Scutia buxifoliaCoronilhaDPPHRadicais livres.This work describes the antioxidant evaluation through the DPPH free radical methodology, the determination of polyphenol dosage by the method of Folin-Ciocalteau and the content of flavonoids in crude extract and fractions of the Scutia buxifolia twigs (coronilha). The content of flavonoids and polyphenols ranged from 102.02 ± 0.71 to 318.82 ± 1.62 milligram of pirogallic acid per gram of dry plant and 83.47 ± 0.93 to 140.71 ± 2.14 milligram of rutin per gram of dry plant, respectively. The IC50 required concentration to inhibit the activity of DPPH at 50% was: crude extract > CH2Cl2 > AcOEt > n-BuOH. In this study it was established a high positive correlation between fractions of phenolic compounds and antioxidant activity of these (0.99). These results indicate that S. buxifolia has chemicals that are able to catch free radicals, promising compounds in the search for antioxidant drugs against diseases from oxidative stress, being the n-BuOH and AcOEt fractions the most effective ones.O presente trabalho descreve a avaliação da atividade antioxidante pela metodologia do radical livre DPPH, o doseamento de polifenóis pelo método de Folin-Ciocalteau e teor de flavonóides no extrato bruto e nas frações dos ramos de Scutia buxifolia (coronilha). O conteúdo de polifenóis e flavonóides variaram de 102,02 ± 0,71 a 318,82 ± 1,62 miligrama de ácido pirogálico por grama de planta seca e 83,47 ± 0,93 a 140,71 ± 2,14 miligrama de rutina por grama de planta seca, respectivamente. O IC50, concentração necessária para inibir a atividade do DPPH em 50% foi: extrato bruto > CH2Cl2 > AcOEt > n-BuOH. No presente estudo foi possível estabelecer uma alta correlação positiva entre compostos fenólicos das frações e a atividade antioxidante destas (0,99). Estes resultados indicam que S. buxifolia possui Substâncias químicas capazes de capturarem radicais livres, compostos promissores na busca de fármacos antioxidantes contra doenças decorrentes do estresse oxidativo, sendo as frações n-BuOH e AcOEt as mais efetivas.Universidade Federal de Santa Maria2009-07-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.ufsm.br/revistasaude/article/view/652710.5902/223658346527Saúde (Santa Maria); Revista do Centro de Ciências da Saúde. Vol. 35 - n.1, 2009; 34-38Saúde (Santa Maria); Revista do Centro de Ciências da Saúde. Vol. 35 - n.1, 2009; 34-382236-58340103-4499reponame:Saúde (Santa Maria)instname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMporhttps://periodicos.ufsm.br/revistasaude/article/view/6527/3988Boligon, Aline AugustiMagoga, Bruna RibeiroFeltrin, Andrieli CasselJanovik, VanessaAthayde, Margareth Lindeinfo:eu-repo/semantics/openAccess2020-03-25T19:41:46Zoai:ojs.pkp.sfu.ca:article/6527Revistahttps://periodicos.ufsm.br/revistasaudePUBhttps://periodicos.ufsm.br/revistasaude/oairevistasaude.ufsm@gmail.com || amanda.revsaude@gmail.com || beatriz.revsaude@gmail.com2236-58342236-5834opendoar:2020-03-25T19:41:46Saúde (Santa Maria) - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
Potencial antioxidante in vitro, conteúdo de fenóis e flavonóides nos ramos de Scutia buxifolia Reissek
title In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
spellingShingle In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
Boligon, Aline Augusti
Scutia buxifolia
Coronilha
DPPH
Free radicals.
Scutia buxifolia
Coronilha
DPPH
Radicais livres.
title_short In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
title_full In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
title_fullStr In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
title_full_unstemmed In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
title_sort In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
author Boligon, Aline Augusti
author_facet Boligon, Aline Augusti
Magoga, Bruna Ribeiro
Feltrin, Andrieli Cassel
Janovik, Vanessa
Athayde, Margareth Linde
author_role author
author2 Magoga, Bruna Ribeiro
Feltrin, Andrieli Cassel
Janovik, Vanessa
Athayde, Margareth Linde
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Boligon, Aline Augusti
Magoga, Bruna Ribeiro
Feltrin, Andrieli Cassel
Janovik, Vanessa
Athayde, Margareth Linde
dc.subject.por.fl_str_mv Scutia buxifolia
Coronilha
DPPH
Free radicals.
Scutia buxifolia
Coronilha
DPPH
Radicais livres.
topic Scutia buxifolia
Coronilha
DPPH
Free radicals.
Scutia buxifolia
Coronilha
DPPH
Radicais livres.
description This work describes the antioxidant evaluation through the DPPH free radical methodology, the determination of polyphenol dosage by the method of Folin-Ciocalteau and the content of flavonoids in crude extract and fractions of the Scutia buxifolia twigs (coronilha). The content of flavonoids and polyphenols ranged from 102.02 ± 0.71 to 318.82 ± 1.62 milligram of pirogallic acid per gram of dry plant and 83.47 ± 0.93 to 140.71 ± 2.14 milligram of rutin per gram of dry plant, respectively. The IC50 required concentration to inhibit the activity of DPPH at 50% was: crude extract > CH2Cl2 > AcOEt > n-BuOH. In this study it was established a high positive correlation between fractions of phenolic compounds and antioxidant activity of these (0.99). These results indicate that S. buxifolia has chemicals that are able to catch free radicals, promising compounds in the search for antioxidant drugs against diseases from oxidative stress, being the n-BuOH and AcOEt fractions the most effective ones.
publishDate 2009
dc.date.none.fl_str_mv 2009-07-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.ufsm.br/revistasaude/article/view/6527
10.5902/223658346527
url https://periodicos.ufsm.br/revistasaude/article/view/6527
identifier_str_mv 10.5902/223658346527
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.ufsm.br/revistasaude/article/view/6527/3988
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv Saúde (Santa Maria); Revista do Centro de Ciências da Saúde. Vol. 35 - n.1, 2009; 34-38
Saúde (Santa Maria); Revista do Centro de Ciências da Saúde. Vol. 35 - n.1, 2009; 34-38
2236-5834
0103-4499
reponame:Saúde (Santa Maria)
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Saúde (Santa Maria)
collection Saúde (Santa Maria)
repository.name.fl_str_mv Saúde (Santa Maria) - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv revistasaude.ufsm@gmail.com || amanda.revsaude@gmail.com || beatriz.revsaude@gmail.com
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