Resistance to colistin in isolates of newborn hemocultures admitted in a school hospital

• Autor(a) principal: Rampelotto, Roberta Filipini
• Data de Publicação: 2017
• Outros Autores: Freitas, Flávia Padilha de, Lorenzoni, Vinicius Victor, Serafin, Marissa Bolson, Coelho, Silvana Silveira, Hörner, Rosmari
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Saúde (Santa Maria)
• Texto Completo: https://periodicos.ufsm.br/revistasaude/article/view/28469
• topic: Sepsis; Newborn; Colistin; Sepse; Recém-nascido; Colistina

The objective of this study was to evaluate resistance against colistin in isolates of blood cultures from newborns (NB) admitted in a School Hospital in a 4-year period. The identification tests and antimicrobial susceptibility profiles were performed using automated systems. At the period of this study, 923 blood cultures were positive, 92.09% (850/923) were caused by Gram-positive microorganisms and 7.91% (73/923) by Gram-negative. Of these, two isolates were resistant to colistin: Acinetobacter baumannii and Sphingomonas paucimobilis; and a Pseudomonas aeruginosa isolate showed an intermediate profile to this antimicrobial, also presenting resistance to carbapenems. This profile is worrying since these antimicrobials are the last alternative for the treatment of infections caused by multiresistant Gram-negative bacilli. The results of this study indicate the follow-up of the monitoring of this resistance.