Toxoplasma gondii - seroprevalence in HIV patients in southern Brazil

• Autor(a) principal: Silva, Claudinei Mesquita da
• Data de Publicação: 2017
• Outros Autores: Peder, Leyde Daiane de, Menolli, Rafael Andrade, Takizawa, Maria das Graças Marciano Hirata, Takizawa, Marcelo Caname Hirata, Horvath, Josana Dranka, Silva, Eraldo Schunk, Teixeira, Jorge Juarez Vieira, Bertolini, Dennis Armando
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Saúde (Santa Maria)
• Texto Completo: https://periodicos.ufsm.br/revistasaude/article/view/25588
• topic: HIV; Toxoplasmosis; Epidemiology; HIV; Toxoplasmose; Epidemiologia

The objective of this study was to estimate the seroprevalence of Toxoplasma gondii and its association with predictors in HIV-infected patients. A cross-sectional study with HIV-infected patients attended at a referral center in Southern Brazil between 2005 and 2014. The seroprevalence of T. gondii was 57.90%, being significantly higher in patients belonging to 30-49 years (Odds Ratio (OR) 5.2, 95% CI 1.57-17.10, p=0.007) and ≥ 50 years (OR 4.1, 95% CI 1.22-13.77, p=0,02, female (OR 3.3, 95% CI 1.33-7.32, p <0.0001) and with ≤ 8 years of education (OR 2.2, 95% CI 1.62-2, 93, p <0.0001). Single patients with HIV diagnosis time ≤ 1 year had a protective factor (OR 0.5, 95% CI 0.25-0.99, p = 0.04) and (OR 0.5, CI 0.37 -0.73, p <0.0001), respectively. The findings report high seroprevalence for T. gondii in HIV-infected patients.