Hepatitis C prevalence in a priority municipality for tuberculosis: single center study

• Autor(a) principal: Peresi-Lordelo, Eliana
• Data de Publicação: 2023
• Outros Autores: Diório, Aline Cintra Nemer, Pereira, Ana Carolina Munuera, Martins, Bruna Alves, Kito, Bruno Kenji, Boni, Fernando Nunes Gavioli, Croscioli, Yara Felippe Bueno, Mazaro, Paulo José Mascarenhas, Matarazo, João Guilherme Araujo, Paulin, Priscila
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Saúde (Santa Maria)
• Texto Completo: https://periodicos.ufsm.br/revistasaude/article/view/72042
• topic: Tuberculosis; Hepatitis C; Prevalence; Tuberculose; Hepatite C; Prevalência

Objective: Hepatitis C virus (HCV) infection could be a risk factor for the development of active tuberculosis (TB) and, despite the proven prevalence of tuberculosis/hepatitis C (TB/HCV) co-infection, there are still few studies addressing this relationship. The aim of the present study was to assess the prevalence of hepatitis C in patients with TB and its association with clinical and epidemiological data. Methods: Patients with TB (n=34), older than 18 years, of both genders, were studied. Anti-HCV antibodies were evaluated by ELISA and the clinical and epidemiological data were obtained from medical records. Analyzes were performed using Fisher and Mann-Whitney tests (p<0.05). Results: Among the 34 TB patients assessed, 3 had anti-HCV antibodies demonstrating a seroprevalence of 8.82%. There was no association of TB/HCV with clinical and epidemiological data in the studied population. Final Considerations: Due to the association TB/HCV being a reality, the introduction of a routine screening for hepatitis C markers before antituberculosis treatment would be recommended for a better follow-up of patients and reduced risk of hepatotoxicity.