EFFECT OF AQUEOUS SCUTIA BUXIFOLIA EXTRACT ON SERUM ALBUMIN AND, RAT’S BODY WEIGHT

• Autor(a) principal: Freitas, Robson Borba de
• Data de Publicação: 2015
• Outros Autores: Jesus, Roberta da Silva, Araldi, Isabel Cristina da Costa, Rovan, Bruno Tomazele, Brum, Thiele Faccim de, Piana, Mariana, Boligon, Aline Augusti, Pigatto, Glauce Regina, Lopes, Gilberti Helena Hübscher, Athayde, Margareth Linde, Bauermann, Liliane de Freitas
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Saúde (Santa Maria)
• Texto Completo: https://periodicos.ufsm.br/revistasaude/article/view/13726

Scutia buxifolia is a medicinal plant used for the treatment of cardiac diseases but little know about its toxicity on liver. Wistar rats (n=32) were divided into 4 groups: control and treated groups with 100, 200 and, 400 mg of lyophilized aqueous extract of S. buxifolia (EASB)/ kg of body weight, daily, during 30 days. The blood of animals was collected on 15th and 30th day of experiment for serum albumin dosage. The blood samples were centrifugated (3000 rpm) for 15 minutes.  The present study was planned to explore the hepatotoxic effect of EASB, which was assessed by total body weight, liver weight and, serum albumin. EASB did not alter the parameters analyzed. This way, EASB was not toxic for the liver in the dosages used.