Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional Manancial UFSM |
Texto Completo: | http://repositorio.ufsm.br/handle/1/6170 |
Resumo: | The non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in Endodontics and when associated with some risk factors, such as concomitant use of other drugs, may develop undesirable and possibly serious effects. This cross-sectional study evaluated, through data collecting on dental records, potential interactions among the most commonly prescribed NSAIDs and medications used by patients treated in the Integrated Clinical Dentistry of UFSM, from 2007 to 2011. The data were processed on the EpiData and the statistical analysis was performed with SPSS Software. For analysis of interactions between drugs two tertiary bibliographic source were used: the book Drug Interaction Facts and computerized tool Drugdex in the Micromedex. Potential drug interactions with NSAIDs occurred with 20.2% of the drugs related by patients. The most common consequences in this context were gastrointestinal bleeding, decrease antihypertensive effect and renal failure. In relation to gravity and documentation of interaction, there was a higher frequency of the important gravity and well-documented in the issue of pharmacological interaction. Hence, special attention must be given to the elderly and other patients using several drugs at the same time alongside with educational initiatives focused on a more safe prescription method should be taught in educational institutions. |
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2016-02-292016-02-292015-08-17BÉE, Lais Regina. POTENTIAL INTERACTIONS BETWEEN NSAIDs PRESCRIBED IN ENDODONTICS AND DRUGS IN USE BY DENTAL PATIENT. 2015. 43 f. Dissertação (Mestrado em Odontologia) - Universidade Federal de Santa Maria, Santa Maria, 2015.http://repositorio.ufsm.br/handle/1/6170The non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in Endodontics and when associated with some risk factors, such as concomitant use of other drugs, may develop undesirable and possibly serious effects. This cross-sectional study evaluated, through data collecting on dental records, potential interactions among the most commonly prescribed NSAIDs and medications used by patients treated in the Integrated Clinical Dentistry of UFSM, from 2007 to 2011. The data were processed on the EpiData and the statistical analysis was performed with SPSS Software. For analysis of interactions between drugs two tertiary bibliographic source were used: the book Drug Interaction Facts and computerized tool Drugdex in the Micromedex. Potential drug interactions with NSAIDs occurred with 20.2% of the drugs related by patients. The most common consequences in this context were gastrointestinal bleeding, decrease antihypertensive effect and renal failure. In relation to gravity and documentation of interaction, there was a higher frequency of the important gravity and well-documented in the issue of pharmacological interaction. Hence, special attention must be given to the elderly and other patients using several drugs at the same time alongside with educational initiatives focused on a more safe prescription method should be taught in educational institutions.Os anti-inflamatórios não esteroides (AINEs) são fármacos amplamente utilizados em Endodontia e, quando associadas a alguns fatores de risco, como uso concomitante de outros medicamentos, podem desenvolver efeitos indesejados e possivelmente graves. Esse estudo transversal avaliou, por meio de uma coleta de dados nos prontuários odontológicos, as potenciais interações entre os AINEs mais comumente prescritos e os medicamentos em uso pelos pacientes atendidos nas Clínicas Integradas do Curso de Odontologia da UFSM, no período de 2007 a 2011. Os dados foram codificados no Programa EpiData e a análise estatística foi realizada com o Software SPSS. Para análise das interações entre os fármacos foram utilizadas duas fontes bibliográficas terciárias: o livro Drug Interaction Facts e a ferramenta informatizada Drugdex do Micromedex. As potenciais interações medicamentosas com AINEs ocorreram em 20,2% dos medicamentos relatados pelos pacientes. As consequências mais frequentes nesse contexto foram sangramento gastrointestinal, diminuição do efeito anti-hipertensivo e insuficiência renal. Em relação à gravidade e a documentação da interação, observou-se maior frequência de gravidade importante e bem documentada no quesito interação farmacológica. Então, atenção especial deve ser dada a pacientes idosos e outros pacientes que utilizem diversos medicamentos de forma paralela e iniciativas educacionais focadas em um método de prescrição mais seguro devem ser lecionadas em instituições de ensino.application/pdfporUniversidade Federal de Santa MariaPrograma de Pós-Graduação em Ciências OdontológicasUFSMBROdontologiaAnti-inflamatórios não esteroidesEfeitos adversosInterações de medicamentosAdverse effectsAnti-Inflammatory agents non-steroidalDrug interactionsCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIAInterações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicosPotential interactions between NSAIDs prescribed in endodontics and drugs in use by dental patientinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisSchmitz, Marcia da Silvahttp://lattes.cnpq.br/4239733753424639Montagner, Franciscohttp://lattes.cnpq.br/2937031469516770Zanatta, Fabricio Batistinhttp://lattes.cnpq.br/0682875622264684http://lattes.cnpq.br/9547795519299876Bée, Lais Regina400200000000400300300500300fc4da2ba-b68a-44fb-b92f-a1a7893aad09102628b1-d101-4ac8-bc41-25fda8eafe467ded886f-6ce0-4336-aaec-1e9ba0d387f46a50227b-ffe3-4a86-aa76-9cc301a17a74info:eu-repo/semantics/openAccessreponame:Repositório Institucional Manancial UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMORIGINALBEE, LAIS REGINA.pdfapplication/pdf3257388http://repositorio.ufsm.br/bitstream/1/6170/1/BEE%2c%20LAIS%20REGINA.pdff168a346dfe5ca4b45379cf3fe302979MD51TEXTBEE, LAIS REGINA.pdf.txtBEE, LAIS REGINA.pdf.txtExtracted texttext/plain55981http://repositorio.ufsm.br/bitstream/1/6170/2/BEE%2c%20LAIS%20REGINA.pdf.txt870928d752e0541b0ca89982892e7091MD52THUMBNAILBEE, LAIS REGINA.pdf.jpgBEE, LAIS REGINA.pdf.jpgIM Thumbnailimage/jpeg4969http://repositorio.ufsm.br/bitstream/1/6170/3/BEE%2c%20LAIS%20REGINA.pdf.jpgbed0022dcc97a9ef489ec110e36b9a7eMD531/61702022-05-10 09:50:38.936oai:repositorio.ufsm.br:1/6170Repositório Institucionalhttp://repositorio.ufsm.br/PUBhttp://repositorio.ufsm.br/oai/requestouvidoria@ufsm.bropendoar:39132022-05-10T12:50:38Repositório Institucional Manancial UFSM - Universidade Federal de Santa Maria (UFSM)false |
dc.title.por.fl_str_mv |
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos |
dc.title.alternative.eng.fl_str_mv |
Potential interactions between NSAIDs prescribed in endodontics and drugs in use by dental patient |
title |
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos |
spellingShingle |
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos Bée, Lais Regina Anti-inflamatórios não esteroides Efeitos adversos Interações de medicamentos Adverse effects Anti-Inflammatory agents non-steroidal Drug interactions CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA |
title_short |
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos |
title_full |
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos |
title_fullStr |
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos |
title_full_unstemmed |
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos |
title_sort |
Interações potenciais entre AINEs prescritos em endodontia e medicamentos em uso pelos pacientes odontológicos |
author |
Bée, Lais Regina |
author_facet |
Bée, Lais Regina |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Schmitz, Marcia da Silva |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/4239733753424639 |
dc.contributor.referee1.fl_str_mv |
Montagner, Francisco |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/2937031469516770 |
dc.contributor.referee2.fl_str_mv |
Zanatta, Fabricio Batistin |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/0682875622264684 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/9547795519299876 |
dc.contributor.author.fl_str_mv |
Bée, Lais Regina |
contributor_str_mv |
Schmitz, Marcia da Silva Montagner, Francisco Zanatta, Fabricio Batistin |
dc.subject.por.fl_str_mv |
Anti-inflamatórios não esteroides Efeitos adversos Interações de medicamentos |
topic |
Anti-inflamatórios não esteroides Efeitos adversos Interações de medicamentos Adverse effects Anti-Inflammatory agents non-steroidal Drug interactions CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA |
dc.subject.eng.fl_str_mv |
Adverse effects Anti-Inflammatory agents non-steroidal Drug interactions |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA |
description |
The non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in Endodontics and when associated with some risk factors, such as concomitant use of other drugs, may develop undesirable and possibly serious effects. This cross-sectional study evaluated, through data collecting on dental records, potential interactions among the most commonly prescribed NSAIDs and medications used by patients treated in the Integrated Clinical Dentistry of UFSM, from 2007 to 2011. The data were processed on the EpiData and the statistical analysis was performed with SPSS Software. For analysis of interactions between drugs two tertiary bibliographic source were used: the book Drug Interaction Facts and computerized tool Drugdex in the Micromedex. Potential drug interactions with NSAIDs occurred with 20.2% of the drugs related by patients. The most common consequences in this context were gastrointestinal bleeding, decrease antihypertensive effect and renal failure. In relation to gravity and documentation of interaction, there was a higher frequency of the important gravity and well-documented in the issue of pharmacological interaction. Hence, special attention must be given to the elderly and other patients using several drugs at the same time alongside with educational initiatives focused on a more safe prescription method should be taught in educational institutions. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-08-17 |
dc.date.accessioned.fl_str_mv |
2016-02-29 |
dc.date.available.fl_str_mv |
2016-02-29 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BÉE, Lais Regina. POTENTIAL INTERACTIONS BETWEEN NSAIDs PRESCRIBED IN ENDODONTICS AND DRUGS IN USE BY DENTAL PATIENT. 2015. 43 f. Dissertação (Mestrado em Odontologia) - Universidade Federal de Santa Maria, Santa Maria, 2015. |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufsm.br/handle/1/6170 |
identifier_str_mv |
BÉE, Lais Regina. POTENTIAL INTERACTIONS BETWEEN NSAIDs PRESCRIBED IN ENDODONTICS AND DRUGS IN USE BY DENTAL PATIENT. 2015. 43 f. Dissertação (Mestrado em Odontologia) - Universidade Federal de Santa Maria, Santa Maria, 2015. |
url |
http://repositorio.ufsm.br/handle/1/6170 |
dc.language.iso.fl_str_mv |
por |
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por |
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400200000000 |
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400 300 300 500 300 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
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Programa de Pós-Graduação em Ciências Odontológicas |
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UFSM |
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BR |
dc.publisher.department.fl_str_mv |
Odontologia |
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Universidade Federal de Santa Maria |
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