Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays

Detalhes bibliográficos
Autor(a) principal: Silva,José Darlan Alves da
Data de Publicação: 2019
Outros Autores: Nogueira,Cláudio Rodrigo, Vieira,Maria do Carmo, Heredia-Vieira,Silvia Cristina, Barufatti,Alexeia, Crispim,Bruno do Amaral, Francisco,Luiza Flávia Veiga, Viana,Lucilene Finoto, Cardoso,Claudia Andrea Lima
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Ciência Rural
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000800753
Resumo: ABSTRACT: The aqueous extract of Aristolochia triangularis leaves showed activity against Artemia salina larvae, with an LD50 of 370.6 µg/mL. In experiments with Allium cepa seeds, the extract caused a 51.26% reduction in the germination index, inhibited mean root growth, and was cytotoxic at concentrations of 668 and 2,000 µg/mL. Its antioxidant activity was additionally assessed in this research and the ferric reducing antioxidant power value was found to be 391.2 µM/g. Such health-beneficial property can be attributed partly to the total phenolic content, spectrophotometrically determined as 52.67 mg/g. The occurrence of cytotoxicity suggested caution when consuming teas from A. triangularis leaves for medicinal purposes, and equally reveals the need for further studies to investigate their adverse effects.
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spelling Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassayscipó-mil-homensinfusiontoxicityABSTRACT: The aqueous extract of Aristolochia triangularis leaves showed activity against Artemia salina larvae, with an LD50 of 370.6 µg/mL. In experiments with Allium cepa seeds, the extract caused a 51.26% reduction in the germination index, inhibited mean root growth, and was cytotoxic at concentrations of 668 and 2,000 µg/mL. Its antioxidant activity was additionally assessed in this research and the ferric reducing antioxidant power value was found to be 391.2 µM/g. Such health-beneficial property can be attributed partly to the total phenolic content, spectrophotometrically determined as 52.67 mg/g. The occurrence of cytotoxicity suggested caution when consuming teas from A. triangularis leaves for medicinal purposes, and equally reveals the need for further studies to investigate their adverse effects.Universidade Federal de Santa Maria2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000800753Ciência Rural v.49 n.8 2019reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/0103-8478cr20190091info:eu-repo/semantics/openAccessSilva,José Darlan Alves daNogueira,Cláudio RodrigoVieira,Maria do CarmoHeredia-Vieira,Silvia CristinaBarufatti,AlexeiaCrispim,Bruno do AmaralFrancisco,Luiza Flávia VeigaViana,Lucilene FinotoCardoso,Claudia Andrea Limaeng2019-08-12T00:00:00ZRevista
dc.title.none.fl_str_mv Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays
title Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays
spellingShingle Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays
Silva,José Darlan Alves da
cipó-mil-homens
infusion
toxicity
title_short Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays
title_full Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays
title_fullStr Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays
title_full_unstemmed Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays
title_sort Toxicological properties of an aqueous extract of Aristolochia triangularis leaves, using the brine shrimp lethality and Allium cepa bioassays
author Silva,José Darlan Alves da
author_facet Silva,José Darlan Alves da
Nogueira,Cláudio Rodrigo
Vieira,Maria do Carmo
Heredia-Vieira,Silvia Cristina
Barufatti,Alexeia
Crispim,Bruno do Amaral
Francisco,Luiza Flávia Veiga
Viana,Lucilene Finoto
Cardoso,Claudia Andrea Lima
author_role author
author2 Nogueira,Cláudio Rodrigo
Vieira,Maria do Carmo
Heredia-Vieira,Silvia Cristina
Barufatti,Alexeia
Crispim,Bruno do Amaral
Francisco,Luiza Flávia Veiga
Viana,Lucilene Finoto
Cardoso,Claudia Andrea Lima
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva,José Darlan Alves da
Nogueira,Cláudio Rodrigo
Vieira,Maria do Carmo
Heredia-Vieira,Silvia Cristina
Barufatti,Alexeia
Crispim,Bruno do Amaral
Francisco,Luiza Flávia Veiga
Viana,Lucilene Finoto
Cardoso,Claudia Andrea Lima
dc.subject.por.fl_str_mv cipó-mil-homens
infusion
toxicity
topic cipó-mil-homens
infusion
toxicity
description ABSTRACT: The aqueous extract of Aristolochia triangularis leaves showed activity against Artemia salina larvae, with an LD50 of 370.6 µg/mL. In experiments with Allium cepa seeds, the extract caused a 51.26% reduction in the germination index, inhibited mean root growth, and was cytotoxic at concentrations of 668 and 2,000 µg/mL. Its antioxidant activity was additionally assessed in this research and the ferric reducing antioxidant power value was found to be 391.2 µM/g. Such health-beneficial property can be attributed partly to the total phenolic content, spectrophotometrically determined as 52.67 mg/g. The occurrence of cytotoxicity suggested caution when consuming teas from A. triangularis leaves for medicinal purposes, and equally reveals the need for further studies to investigate their adverse effects.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000800753
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000800753
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0103-8478cr20190091
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv Ciência Rural v.49 n.8 2019
reponame:Ciência Rural
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Ciência Rural
collection Ciência Rural
repository.name.fl_str_mv
repository.mail.fl_str_mv
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