Radiation therapy for oral melanoma in dogs: A retrospective study
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Ciência Rural |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000400603 |
Resumo: | ABSTRACT: Our retrospective study evaluated the survival of 24 dogs with unresectable malignant melanoma treated with radiation therapy. Fifteen dogs were treated with radiation therapy (RT) and chemotherapy (CT), five with surgery followed by RT and CT, three with palliative RT, and one with electrochemotherapy associated with RT. All dogs were treated with an orthovoltage Stabilipan I. The protocol used was three or four weekly fractions of 8 Gy. Carboplatin was administered every 21 days, a total of four times. Five percent of dogs were classified as having stage I melanoma, 17% as stage II, 50% as stage III, and 17% as stage IV. Sixty-four percent had a partial response to treatment, 29% achieved complete remission, and 7% remained in a stable disease state. The mean survival time was 390 days for stage I, 286 days for stage II, 159 days for stage III, and 90 days for stage IV. We concluded that radiation therapy can be considered a viable alternative for the palliative treatment of canine oral melanoma. |
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Ciência rural (Online) |
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Radiation therapy for oral melanoma in dogs: A retrospective studyneoplasiaradiationoral cavityABSTRACT: Our retrospective study evaluated the survival of 24 dogs with unresectable malignant melanoma treated with radiation therapy. Fifteen dogs were treated with radiation therapy (RT) and chemotherapy (CT), five with surgery followed by RT and CT, three with palliative RT, and one with electrochemotherapy associated with RT. All dogs were treated with an orthovoltage Stabilipan I. The protocol used was three or four weekly fractions of 8 Gy. Carboplatin was administered every 21 days, a total of four times. Five percent of dogs were classified as having stage I melanoma, 17% as stage II, 50% as stage III, and 17% as stage IV. Sixty-four percent had a partial response to treatment, 29% achieved complete remission, and 7% remained in a stable disease state. The mean survival time was 390 days for stage I, 286 days for stage II, 159 days for stage III, and 90 days for stage IV. We concluded that radiation therapy can be considered a viable alternative for the palliative treatment of canine oral melanoma.Universidade Federal de Santa Maria2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000400603Ciência Rural v.48 n.4 2018reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/0103-8478cr20160396info:eu-repo/semantics/openAccessCunha,Simone Carvalho dos SantosCorgozinho,Katia BarãoSilva,Franciele Basso FernandesSilva,Kassia Valéria Gomes Coelho daFerreira,Ana Maria Reiseng2018-04-12T00:00:00ZRevista |
dc.title.none.fl_str_mv |
Radiation therapy for oral melanoma in dogs: A retrospective study |
title |
Radiation therapy for oral melanoma in dogs: A retrospective study |
spellingShingle |
Radiation therapy for oral melanoma in dogs: A retrospective study Cunha,Simone Carvalho dos Santos neoplasia radiation oral cavity |
title_short |
Radiation therapy for oral melanoma in dogs: A retrospective study |
title_full |
Radiation therapy for oral melanoma in dogs: A retrospective study |
title_fullStr |
Radiation therapy for oral melanoma in dogs: A retrospective study |
title_full_unstemmed |
Radiation therapy for oral melanoma in dogs: A retrospective study |
title_sort |
Radiation therapy for oral melanoma in dogs: A retrospective study |
author |
Cunha,Simone Carvalho dos Santos |
author_facet |
Cunha,Simone Carvalho dos Santos Corgozinho,Katia Barão Silva,Franciele Basso Fernandes Silva,Kassia Valéria Gomes Coelho da Ferreira,Ana Maria Reis |
author_role |
author |
author2 |
Corgozinho,Katia Barão Silva,Franciele Basso Fernandes Silva,Kassia Valéria Gomes Coelho da Ferreira,Ana Maria Reis |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Cunha,Simone Carvalho dos Santos Corgozinho,Katia Barão Silva,Franciele Basso Fernandes Silva,Kassia Valéria Gomes Coelho da Ferreira,Ana Maria Reis |
dc.subject.por.fl_str_mv |
neoplasia radiation oral cavity |
topic |
neoplasia radiation oral cavity |
description |
ABSTRACT: Our retrospective study evaluated the survival of 24 dogs with unresectable malignant melanoma treated with radiation therapy. Fifteen dogs were treated with radiation therapy (RT) and chemotherapy (CT), five with surgery followed by RT and CT, three with palliative RT, and one with electrochemotherapy associated with RT. All dogs were treated with an orthovoltage Stabilipan I. The protocol used was three or four weekly fractions of 8 Gy. Carboplatin was administered every 21 days, a total of four times. Five percent of dogs were classified as having stage I melanoma, 17% as stage II, 50% as stage III, and 17% as stage IV. Sixty-four percent had a partial response to treatment, 29% achieved complete remission, and 7% remained in a stable disease state. The mean survival time was 390 days for stage I, 286 days for stage II, 159 days for stage III, and 90 days for stage IV. We concluded that radiation therapy can be considered a viable alternative for the palliative treatment of canine oral melanoma. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000400603 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000400603 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0103-8478cr20160396 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
dc.source.none.fl_str_mv |
Ciência Rural v.48 n.4 2018 reponame:Ciência Rural instname:Universidade Federal de Santa Maria (UFSM) instacron:UFSM |
instname_str |
Universidade Federal de Santa Maria (UFSM) |
instacron_str |
UFSM |
institution |
UFSM |
reponame_str |
Ciência Rural |
collection |
Ciência Rural |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1749140552505360384 |