Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2004 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Ciência Rural |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782004000300044 |
Resumo: | A two-month-old lamb showing signs of severe neurological disease characterized by muscular tremors, hypermetria, and motor incoordination was submitted to the Veterinary Pathology Laboratory - Universidade Federal do Rio Grande do Sul, Brazil. At necropsy, the major findings were a marked reduction of the size of the cerebellum and bilateral dilatation of the lateral ventricles. Microscopically, areas of cellular disorganization in the cerebellar cortex, reduction of the granular layer of cerebellum associated with decreased density of cells, and the presence of large cytoplasmic vacuoles in the molecular layer were observed. Neurons of the gray matter of the brain and macrophages of the mesenteric lymph nodes stained positively by the immunohistochemistry test using the monoclonal antibody 15C5 against Bovine Viral Diarrhea Virus. Taken together, those results are consistent with a pestivirus infection, either Border Disease Virus (BDV) or BVDV. |
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Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, BrazilpestivirusBorder DiseasesheepBrazilA two-month-old lamb showing signs of severe neurological disease characterized by muscular tremors, hypermetria, and motor incoordination was submitted to the Veterinary Pathology Laboratory - Universidade Federal do Rio Grande do Sul, Brazil. At necropsy, the major findings were a marked reduction of the size of the cerebellum and bilateral dilatation of the lateral ventricles. Microscopically, areas of cellular disorganization in the cerebellar cortex, reduction of the granular layer of cerebellum associated with decreased density of cells, and the presence of large cytoplasmic vacuoles in the molecular layer were observed. Neurons of the gray matter of the brain and macrophages of the mesenteric lymph nodes stained positively by the immunohistochemistry test using the monoclonal antibody 15C5 against Bovine Viral Diarrhea Virus. Taken together, those results are consistent with a pestivirus infection, either Border Disease Virus (BDV) or BVDV.Universidade Federal de Santa Maria2004-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782004000300044Ciência Rural v.34 n.3 2004reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/S0103-84782004000300044info:eu-repo/semantics/openAccessPescador,Caroline ArgentaCorbellini,Luis GustavoDriemeier,DavidGonçalves,Ricardo KalilCruz,Cláudio Estêvão Fariaseng2004-07-05T00:00:00ZRevista |
dc.title.none.fl_str_mv |
Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil |
title |
Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil |
spellingShingle |
Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil Pescador,Caroline Argenta pestivirus Border Disease sheep Brazil |
title_short |
Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil |
title_full |
Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil |
title_fullStr |
Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil |
title_full_unstemmed |
Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil |
title_sort |
Neurological disorder associated with pestivirus infection in sheep in Rio Grande do Sul, Brazil |
author |
Pescador,Caroline Argenta |
author_facet |
Pescador,Caroline Argenta Corbellini,Luis Gustavo Driemeier,David Gonçalves,Ricardo Kalil Cruz,Cláudio Estêvão Farias |
author_role |
author |
author2 |
Corbellini,Luis Gustavo Driemeier,David Gonçalves,Ricardo Kalil Cruz,Cláudio Estêvão Farias |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Pescador,Caroline Argenta Corbellini,Luis Gustavo Driemeier,David Gonçalves,Ricardo Kalil Cruz,Cláudio Estêvão Farias |
dc.subject.por.fl_str_mv |
pestivirus Border Disease sheep Brazil |
topic |
pestivirus Border Disease sheep Brazil |
description |
A two-month-old lamb showing signs of severe neurological disease characterized by muscular tremors, hypermetria, and motor incoordination was submitted to the Veterinary Pathology Laboratory - Universidade Federal do Rio Grande do Sul, Brazil. At necropsy, the major findings were a marked reduction of the size of the cerebellum and bilateral dilatation of the lateral ventricles. Microscopically, areas of cellular disorganization in the cerebellar cortex, reduction of the granular layer of cerebellum associated with decreased density of cells, and the presence of large cytoplasmic vacuoles in the molecular layer were observed. Neurons of the gray matter of the brain and macrophages of the mesenteric lymph nodes stained positively by the immunohistochemistry test using the monoclonal antibody 15C5 against Bovine Viral Diarrhea Virus. Taken together, those results are consistent with a pestivirus infection, either Border Disease Virus (BDV) or BVDV. |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782004000300044 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782004000300044 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-84782004000300044 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
dc.source.none.fl_str_mv |
Ciência Rural v.34 n.3 2004 reponame:Ciência Rural instname:Universidade Federal de Santa Maria (UFSM) instacron:UFSM |
instname_str |
Universidade Federal de Santa Maria (UFSM) |
instacron_str |
UFSM |
institution |
UFSM |
reponame_str |
Ciência Rural |
collection |
Ciência Rural |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1749140525228752896 |