Equine acute erythroid leukemia

Detalhes bibliográficos
Autor(a) principal: Panziera,Welden
Data de Publicação: 2015
Outros Autores: Tessele,Bianca, Bianchi,Ronaldo, Tochetto,Camila, De La Corte,Flávio, Brass,Karin, Fighera,Rafael
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Ciência Rural
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015001202214
Resumo: Acute erythroid leukemia (AML M6) is a hematopoietic neoplasm frequently described in cats and mice, rarely in other animal species. This report describes a case of AML M6 in a yearling Thoroughbred filly. Clinically the horse presented marked pale mucous membranes and exercise intolerance. In addition, the owner and referring veterinarian reported a 30-day history of progressive weight loss. The CBC revealed severe anemia and leukopenia by neutropenia. Cytology evaluation obtained from bone marrow fine needle aspirates evidenced inversion of the myeloid: erythroid ratio (0.2), with 48% of the nucleated cells corresponding to rubriblasts. In addition to the gross evidence of anemia, necropsy findings consisted of splenomegaly and lymphadenomegaly. The diagnosis of AML M6B was confirmed histologically due to splenomegaly and lymphadenomegaly, secondary to neoplastic metastasization.
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spelling Equine acute erythroid leukemiamyeloproliferative disorderserythremic mielosishematologyhematopathologyAcute erythroid leukemia (AML M6) is a hematopoietic neoplasm frequently described in cats and mice, rarely in other animal species. This report describes a case of AML M6 in a yearling Thoroughbred filly. Clinically the horse presented marked pale mucous membranes and exercise intolerance. In addition, the owner and referring veterinarian reported a 30-day history of progressive weight loss. The CBC revealed severe anemia and leukopenia by neutropenia. Cytology evaluation obtained from bone marrow fine needle aspirates evidenced inversion of the myeloid: erythroid ratio (0.2), with 48% of the nucleated cells corresponding to rubriblasts. In addition to the gross evidence of anemia, necropsy findings consisted of splenomegaly and lymphadenomegaly. The diagnosis of AML M6B was confirmed histologically due to splenomegaly and lymphadenomegaly, secondary to neoplastic metastasization.Universidade Federal de Santa Maria2015-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015001202214Ciência Rural v.45 n.12 2015reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/0103-8478cr20140876info:eu-repo/semantics/openAccessPanziera,WeldenTessele,BiancaBianchi,RonaldoTochetto,CamilaDe La Corte,FlávioBrass,KarinFighera,Rafaeleng2015-12-04T00:00:00ZRevista
dc.title.none.fl_str_mv Equine acute erythroid leukemia
title Equine acute erythroid leukemia
spellingShingle Equine acute erythroid leukemia
Panziera,Welden
myeloproliferative disorders
erythremic mielosis
hematology
hematopathology
title_short Equine acute erythroid leukemia
title_full Equine acute erythroid leukemia
title_fullStr Equine acute erythroid leukemia
title_full_unstemmed Equine acute erythroid leukemia
title_sort Equine acute erythroid leukemia
author Panziera,Welden
author_facet Panziera,Welden
Tessele,Bianca
Bianchi,Ronaldo
Tochetto,Camila
De La Corte,Flávio
Brass,Karin
Fighera,Rafael
author_role author
author2 Tessele,Bianca
Bianchi,Ronaldo
Tochetto,Camila
De La Corte,Flávio
Brass,Karin
Fighera,Rafael
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Panziera,Welden
Tessele,Bianca
Bianchi,Ronaldo
Tochetto,Camila
De La Corte,Flávio
Brass,Karin
Fighera,Rafael
dc.subject.por.fl_str_mv myeloproliferative disorders
erythremic mielosis
hematology
hematopathology
topic myeloproliferative disorders
erythremic mielosis
hematology
hematopathology
description Acute erythroid leukemia (AML M6) is a hematopoietic neoplasm frequently described in cats and mice, rarely in other animal species. This report describes a case of AML M6 in a yearling Thoroughbred filly. Clinically the horse presented marked pale mucous membranes and exercise intolerance. In addition, the owner and referring veterinarian reported a 30-day history of progressive weight loss. The CBC revealed severe anemia and leukopenia by neutropenia. Cytology evaluation obtained from bone marrow fine needle aspirates evidenced inversion of the myeloid: erythroid ratio (0.2), with 48% of the nucleated cells corresponding to rubriblasts. In addition to the gross evidence of anemia, necropsy findings consisted of splenomegaly and lymphadenomegaly. The diagnosis of AML M6B was confirmed histologically due to splenomegaly and lymphadenomegaly, secondary to neoplastic metastasization.
publishDate 2015
dc.date.none.fl_str_mv 2015-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015001202214
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015001202214
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0103-8478cr20140876
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
publisher.none.fl_str_mv Universidade Federal de Santa Maria
dc.source.none.fl_str_mv Ciência Rural v.45 n.12 2015
reponame:Ciência Rural
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Ciência Rural
collection Ciência Rural
repository.name.fl_str_mv
repository.mail.fl_str_mv
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