Renal injury in female dogs with pyometra
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Ciência Rural |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500603 |
Resumo: | ABSTRACT: Pyometra is a common disease in intact female dogs and can cause glomerulopathy and tubular injury. This study aimed to evaluate kidney injury in female dogs with pyometra, as well as progression of the injury during treatment and the markers of this condition. This study analyzed 20 intact female dogs with both clinical and sonographic diagnosis of pyometra. Dogs were treated with intravenous fluids and antibiotics, and an ovariohysterectomy was performed. The following parameters were assessed at eight separate time points: blood pressure; serum creatinine, phosphorus, and urea levels; urinalysis and urinary biochemical parameters [urinary gamma-glutamyl transferase (uGGT) and urinary protein-to-creatinine ratio (UPCR)]; glomerular filtration rate (GFR); and urine output. All dogs showed some degree of kidney injury at the time of pyometra diagnosis. This was transient in most animals, resolving with treatment of the pyometra. Measurement of uGGT and UPCR identified renal parenchymal injury, helping to determine the prognosis of the animals analyzed in the present study. |
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Renal injury in female dogs with pyometrakidney diseasekidney functionurinary GGTurinary protein-to-creatinine ratioglomerular filtration rateABSTRACT: Pyometra is a common disease in intact female dogs and can cause glomerulopathy and tubular injury. This study aimed to evaluate kidney injury in female dogs with pyometra, as well as progression of the injury during treatment and the markers of this condition. This study analyzed 20 intact female dogs with both clinical and sonographic diagnosis of pyometra. Dogs were treated with intravenous fluids and antibiotics, and an ovariohysterectomy was performed. The following parameters were assessed at eight separate time points: blood pressure; serum creatinine, phosphorus, and urea levels; urinalysis and urinary biochemical parameters [urinary gamma-glutamyl transferase (uGGT) and urinary protein-to-creatinine ratio (UPCR)]; glomerular filtration rate (GFR); and urine output. All dogs showed some degree of kidney injury at the time of pyometra diagnosis. This was transient in most animals, resolving with treatment of the pyometra. Measurement of uGGT and UPCR identified renal parenchymal injury, helping to determine the prognosis of the animals analyzed in the present study.Universidade Federal de Santa Maria2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500603Ciência Rural v.47 n.5 2017reponame:Ciência Ruralinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM10.1590/0103-8478cr20160325info:eu-repo/semantics/openAccessFigueiredo,Mariana da SilvaMalm,ChristinaMamão,Leonardo DiasOliveira,Juliana deVeado,Júlio César CambraiaCosta,Mariana PáduaValente,Pâmela Cristina Lopes GurgelHorta,Rodrigo dos SantosCastro,Marina LopesCastro,Aline Gomes deSbaraini,LeilaSouza,Eliana Matias deeng2017-04-05T00:00:00ZRevista |
dc.title.none.fl_str_mv |
Renal injury in female dogs with pyometra |
title |
Renal injury in female dogs with pyometra |
spellingShingle |
Renal injury in female dogs with pyometra Figueiredo,Mariana da Silva kidney disease kidney function urinary GGT urinary protein-to-creatinine ratio glomerular filtration rate |
title_short |
Renal injury in female dogs with pyometra |
title_full |
Renal injury in female dogs with pyometra |
title_fullStr |
Renal injury in female dogs with pyometra |
title_full_unstemmed |
Renal injury in female dogs with pyometra |
title_sort |
Renal injury in female dogs with pyometra |
author |
Figueiredo,Mariana da Silva |
author_facet |
Figueiredo,Mariana da Silva Malm,Christina Mamão,Leonardo Dias Oliveira,Juliana de Veado,Júlio César Cambraia Costa,Mariana Pádua Valente,Pâmela Cristina Lopes Gurgel Horta,Rodrigo dos Santos Castro,Marina Lopes Castro,Aline Gomes de Sbaraini,Leila Souza,Eliana Matias de |
author_role |
author |
author2 |
Malm,Christina Mamão,Leonardo Dias Oliveira,Juliana de Veado,Júlio César Cambraia Costa,Mariana Pádua Valente,Pâmela Cristina Lopes Gurgel Horta,Rodrigo dos Santos Castro,Marina Lopes Castro,Aline Gomes de Sbaraini,Leila Souza,Eliana Matias de |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Figueiredo,Mariana da Silva Malm,Christina Mamão,Leonardo Dias Oliveira,Juliana de Veado,Júlio César Cambraia Costa,Mariana Pádua Valente,Pâmela Cristina Lopes Gurgel Horta,Rodrigo dos Santos Castro,Marina Lopes Castro,Aline Gomes de Sbaraini,Leila Souza,Eliana Matias de |
dc.subject.por.fl_str_mv |
kidney disease kidney function urinary GGT urinary protein-to-creatinine ratio glomerular filtration rate |
topic |
kidney disease kidney function urinary GGT urinary protein-to-creatinine ratio glomerular filtration rate |
description |
ABSTRACT: Pyometra is a common disease in intact female dogs and can cause glomerulopathy and tubular injury. This study aimed to evaluate kidney injury in female dogs with pyometra, as well as progression of the injury during treatment and the markers of this condition. This study analyzed 20 intact female dogs with both clinical and sonographic diagnosis of pyometra. Dogs were treated with intravenous fluids and antibiotics, and an ovariohysterectomy was performed. The following parameters were assessed at eight separate time points: blood pressure; serum creatinine, phosphorus, and urea levels; urinalysis and urinary biochemical parameters [urinary gamma-glutamyl transferase (uGGT) and urinary protein-to-creatinine ratio (UPCR)]; glomerular filtration rate (GFR); and urine output. All dogs showed some degree of kidney injury at the time of pyometra diagnosis. This was transient in most animals, resolving with treatment of the pyometra. Measurement of uGGT and UPCR identified renal parenchymal injury, helping to determine the prognosis of the animals analyzed in the present study. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500603 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000500603 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0103-8478cr20160325 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria |
dc.source.none.fl_str_mv |
Ciência Rural v.47 n.5 2017 reponame:Ciência Rural instname:Universidade Federal de Santa Maria (UFSM) instacron:UFSM |
instname_str |
Universidade Federal de Santa Maria (UFSM) |
instacron_str |
UFSM |
institution |
UFSM |
reponame_str |
Ciência Rural |
collection |
Ciência Rural |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1749140551307886592 |