Bartholin’s gland adenoma in a Saanen goat

• Autor(a) principal: Moreira,Jessica Regina
• Data de Publicação: 2018
• Outros Autores: Oliveira,Thalita Evani Silva de, Tongu,Eriky Akio de Oliveira, Leite,Raissa Oliveira, Nogueira,Geison Morel, Michelazzo,Mariana de Mello Zanim, Delfiol,Diego José Zanzarini, Saut,João Paulo Elsen, Headley,Selwyn Arlington
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Ciência Rural
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000100501
• topic: Histopathology; ki-67 protein; adenoma; major vestibular glands

ABSTRACT: Tumors affecting Bartholin’s gland are considered rare in human medicine; there are few reports in the veterinary literature, with descriptions occurring only in cows. This article described the clinical and pathological findings associated with Bartholin’s gland adenoma in a goat. Clinically, a 7-year-old pregnant Saanen goat presented bilateral enlargement of the vulva that did not regress spontaneously after parturition. Grossly, these vulvar masses were multilobulated, contained cystic areas from which oozed a whitish fluid. Histopathology revealed an adenoma characterized by the proliferation of irregularly shaped neoplastic epithelial cells that formed tubular to glandular-like structures. These neoplastic cells demonstrated moderate anisokaryosis and evident nucleoli. The intratumoral proliferation index (PI) was estimated by immunoreactivity with the protein ki-67. Further, the glandular-like structures produced a Periodic Acid-Schiff positive secretion. A diagnosis of Bartholin’s gland adenoma was established due to the anatomic location of the neoplastic growths, the histopathological features, and the PI of the tumor.