Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2

Detalhes bibliográficos
Autor(a) principal: Hartmann, Hellen Fialho
Data de Publicação: 2019
Tipo de documento: Tese
Idioma: por
Título da fonte: Manancial - Repositório Digital da UFSM
dARK ID: ark:/26339/0013000013bcz
Texto Completo: http://repositorio.ufsm.br/handle/1/21687
Resumo: The objectives of this study were to verify the occurrence of intraoperative gastroesophageal reflux (GER) in female dogs submitted to elective neuterind by videolaparoscopy with different pneumoperitoneum pressures and using or not antiemetic and to determine if there is a technique that reduces the occurrence of this event, that is, if there is any pneumoperitoneum pressure that has less influence on the occurrence of GER, as well as if metoclopramide could contribute as a preventive. Sixty-six female dogs, weighing 12.4 ± 2.2 kg, 2.6 ± 1.9 years, with no history of emesis or concomitant pathologies, were included in this study. The dogs were divided into nine groups (OVE C, OVE 8, OVE 10, OVE 12, OVH C, OVH 8, OVH 10, OVH 12 and OVH 8 Metoclopramide). In OVE C, laparotomy ovariectomy was performed; in groups OVE 8, OVE 10 and OVE 12, videolaparoscopic ovariectomy was performed with 8, 10 and 12mmHg of CO2 pressure respectively; in the OVH C group, laparotomy ovariohysterectomy was performed; in the OVH 8, OVH 10 and OVH 12 groups, two portals video-assisted ovariohysterectomy were performed using respectively 8, 10 and 12mmHg of CO2 pressure; In the OVH 8 Metoclopramide group, video-assisted OVH was performed by two portals with 8mmHg of pneumoperitoneum pressure and using metoclopramide in the anesthetic premedication.Todas as cadelas foram submetidas à esofagoscopia e pHmetria esofágica durante a cirurgia. It was not possible to attribute GER events to the decubitus changes inherent to the laparoscopic sterilization processes. Age and weight did not differ between bitches in all groups. Pneumoperitoneum time did not differ between OVE and OVH. None of the different pressures applied differently influenced the occurrence of GER. The higher the initial esophageal pH of the dogs, the lower the occurrence of GER. In all groups the esophageal pHs decreased throughout the surgical period, but the conventional groups remained with higher and more stable pHs. Regarding metoclopramide, two groups of dogs submitted to video-assisted two portals OVH with 8mmHg of CO2 pressure were compared, one of them received metoclopramide at the dose of 0.5mg.kg-1 i.m. at the time of premedication. In this study, there was a high occurrence of GER in both groups (57.1% in the non-metoclopramide group and 71.4% in the metoclopramide group) without any statistical difference between them. In conclusion, videosurgery achieved in a higher occurrence of GER compared to conventional surgeries, regardless of the pressure used and metoclopramide did not prevent or reduce the occurrence of GER in bitches submitted to video-assisted OVH, being the high occurrence attributed to the surgery technique. In this scenario, it is suggested continuous research for laparoscopic techniques that reduce (or avoid) GER, considering the importance of minimal invasion procedures.
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spelling Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2Gastroesophageal reflux in dogs submitted to videolaparoscopic OVE or ovh under different CO2 pressuresCaninoEndoscopiapHmetriaRegurgitação transoperatóriaPneumoperitônioCanineEndoscopypHmetryTransoperative regurgitationPneumoperitoneumCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAThe objectives of this study were to verify the occurrence of intraoperative gastroesophageal reflux (GER) in female dogs submitted to elective neuterind by videolaparoscopy with different pneumoperitoneum pressures and using or not antiemetic and to determine if there is a technique that reduces the occurrence of this event, that is, if there is any pneumoperitoneum pressure that has less influence on the occurrence of GER, as well as if metoclopramide could contribute as a preventive. Sixty-six female dogs, weighing 12.4 ± 2.2 kg, 2.6 ± 1.9 years, with no history of emesis or concomitant pathologies, were included in this study. The dogs were divided into nine groups (OVE C, OVE 8, OVE 10, OVE 12, OVH C, OVH 8, OVH 10, OVH 12 and OVH 8 Metoclopramide). In OVE C, laparotomy ovariectomy was performed; in groups OVE 8, OVE 10 and OVE 12, videolaparoscopic ovariectomy was performed with 8, 10 and 12mmHg of CO2 pressure respectively; in the OVH C group, laparotomy ovariohysterectomy was performed; in the OVH 8, OVH 10 and OVH 12 groups, two portals video-assisted ovariohysterectomy were performed using respectively 8, 10 and 12mmHg of CO2 pressure; In the OVH 8 Metoclopramide group, video-assisted OVH was performed by two portals with 8mmHg of pneumoperitoneum pressure and using metoclopramide in the anesthetic premedication.Todas as cadelas foram submetidas à esofagoscopia e pHmetria esofágica durante a cirurgia. It was not possible to attribute GER events to the decubitus changes inherent to the laparoscopic sterilization processes. Age and weight did not differ between bitches in all groups. Pneumoperitoneum time did not differ between OVE and OVH. None of the different pressures applied differently influenced the occurrence of GER. The higher the initial esophageal pH of the dogs, the lower the occurrence of GER. In all groups the esophageal pHs decreased throughout the surgical period, but the conventional groups remained with higher and more stable pHs. Regarding metoclopramide, two groups of dogs submitted to video-assisted two portals OVH with 8mmHg of CO2 pressure were compared, one of them received metoclopramide at the dose of 0.5mg.kg-1 i.m. at the time of premedication. In this study, there was a high occurrence of GER in both groups (57.1% in the non-metoclopramide group and 71.4% in the metoclopramide group) without any statistical difference between them. In conclusion, videosurgery achieved in a higher occurrence of GER compared to conventional surgeries, regardless of the pressure used and metoclopramide did not prevent or reduce the occurrence of GER in bitches submitted to video-assisted OVH, being the high occurrence attributed to the surgery technique. In this scenario, it is suggested continuous research for laparoscopic techniques that reduce (or avoid) GER, considering the importance of minimal invasion procedures.Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPqCoordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESOs objetivos desse estudo foram verificar a ocorrência de refluxo gastroesofágico (RGE) transoperatório em cadelas submetidas a esterilização eletiva por meio de esterilização eletiva videolaparoscópica com diferentes pressões de pneumoperitônio e utilizando, ou não, antiemético, determinando se existe uma técnica que diminua a ocorrência deste evento. Questiona-se se há alguma pressão de pneumoperitônio que influencie menos na ocorrência de RGE, bem como se a metoclopramida poderia contribuir como preventivo. Foram incluídas neste estudo 63 cadelas, com peso de 12,4±2,2Kg, de 2,6±1,9 anos, sem histórico de êmese ou patologias concomitantes. As cadelas foram distribuídas em nove grupos (OVE C, OVE 8, OVE 10, OVE 12, OVH C, OVH 8, OVH 10, OVH 12 e OVH 8 Metoclopramida). No OVE C, realizou-se a ovariectomia por celiotomia; nos grupos OVE 8, OVE 10 e OVE 12 realizou-se a ovariectomia videolaparoscópica respectivamente com 8, 10 e 12mmHg de pressão de CO2, respectivamente; no grupo OVH C realizou-se a ovariohisterectomia por celiotomia; nos grupos OVH 8, OVH 10 e OVH 12 realizou-se a ovariohisterectomia videoassistida por dois portais utilizando respectivamente 8, 10 e 12mmHg de pressão de CO2, respectivamente; no grupo OVH 8 Metoclopramida realizou-se a OVH videoassistida por dois portais com 8mmHg de pressão de pneumoperitônio e utilizando metoclopramida na pré-medicação anestésica. Todas as cadelas foram submetidas à esofagoscopia e pHmetria esofágica durante a cirurgia. Não foi possível atribuir os eventos de RGE às alterações de decúbito inerentes aos processos de esterilização por videocirurgia. Idade e peso não diferiram entre as cadelas de todos os grupos. O tempo de pneumoperitônio não diferiu entre as OVE e as OVH. Nenhuma das diferentes pressões aplicadas influenciou diferentemente entre si, a ocorrência de RGE. Quanto mais alto o pH esofágico inicial das cadelas, menor a ocorrência de RGE. Em todos os grupos os pHs esofágicos baixaram ao longo do período cirúrgico, porém os grupos convencionais se mantiveram com pHs mais altos e mais estáveis. Quanto à metoclopramida, foram comparados dois grupos de cadelas submetidas à OVH videoassistida por dois portais com 8mmHg de pressão de CO2, um que não recebeu metoclopramida na dose de 0,5mg.kg-1 i.m. no momento da pré-medicação, e outro que recebeu. Neste estudo houve uma alta ocorrência de RGE em ambos os grupos (57,1% no grupo que não recebeu e 71,4% no grupo que recebeu metoclopramida), não havendo diferença estatística entre eles. Conclui-se que as videocirurgias culminaram em maior ocorrência de RGE comparadas às cirurgias convencionais, independentemente da pressão utilizada e a metoclopramida não impediu ou reduziu a ocorrência de RGE em cadelas submetidas à OVH videoassistida, ficando a alta ocorrência atribuída à técnica utilizada. Frente a isto, sugere-se a continuação das buscas por técnicas videocirúrgicas que reduzam (ou isentem) o RGE, tendo em vista a importância dos procedimentos de mínima invasão.Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências RuraisBrun, Maurício Velosohttp://lattes.cnpq.br/3913050752928325Pinto Filho, Saulo Tadeu LemosMüller, Daniel Curvello de MendonçaTrindade-Gerardi, Anelise BonillaGomariz, Francisco MartinezHartmann, Hellen Fialho2021-08-02T18:08:44Z2021-08-02T18:08:44Z2019-12-18info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdfhttp://repositorio.ufsm.br/handle/1/21687ark:/26339/0013000013bczporAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2021-08-03T06:03:44Zoai:repositorio.ufsm.br:1/21687Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2021-08-03T06:03:44Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2
Gastroesophageal reflux in dogs submitted to videolaparoscopic OVE or ovh under different CO2 pressures
title Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2
spellingShingle Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2
Hartmann, Hellen Fialho
Canino
Endoscopia
pHmetria
Regurgitação transoperatória
Pneumoperitônio
Canine
Endoscopy
pHmetry
Transoperative regurgitation
Pneumoperitoneum
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2
title_full Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2
title_fullStr Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2
title_full_unstemmed Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2
title_sort Refluxo gastroesofágico em cadelas submetidas à OVE ou OVH por videocirurgia sob diferentes pressões de CO2
author Hartmann, Hellen Fialho
author_facet Hartmann, Hellen Fialho
author_role author
dc.contributor.none.fl_str_mv Brun, Maurício Veloso
http://lattes.cnpq.br/3913050752928325
Pinto Filho, Saulo Tadeu Lemos
Müller, Daniel Curvello de Mendonça
Trindade-Gerardi, Anelise Bonilla
Gomariz, Francisco Martinez
dc.contributor.author.fl_str_mv Hartmann, Hellen Fialho
dc.subject.por.fl_str_mv Canino
Endoscopia
pHmetria
Regurgitação transoperatória
Pneumoperitônio
Canine
Endoscopy
pHmetry
Transoperative regurgitation
Pneumoperitoneum
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
topic Canino
Endoscopia
pHmetria
Regurgitação transoperatória
Pneumoperitônio
Canine
Endoscopy
pHmetry
Transoperative regurgitation
Pneumoperitoneum
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description The objectives of this study were to verify the occurrence of intraoperative gastroesophageal reflux (GER) in female dogs submitted to elective neuterind by videolaparoscopy with different pneumoperitoneum pressures and using or not antiemetic and to determine if there is a technique that reduces the occurrence of this event, that is, if there is any pneumoperitoneum pressure that has less influence on the occurrence of GER, as well as if metoclopramide could contribute as a preventive. Sixty-six female dogs, weighing 12.4 ± 2.2 kg, 2.6 ± 1.9 years, with no history of emesis or concomitant pathologies, were included in this study. The dogs were divided into nine groups (OVE C, OVE 8, OVE 10, OVE 12, OVH C, OVH 8, OVH 10, OVH 12 and OVH 8 Metoclopramide). In OVE C, laparotomy ovariectomy was performed; in groups OVE 8, OVE 10 and OVE 12, videolaparoscopic ovariectomy was performed with 8, 10 and 12mmHg of CO2 pressure respectively; in the OVH C group, laparotomy ovariohysterectomy was performed; in the OVH 8, OVH 10 and OVH 12 groups, two portals video-assisted ovariohysterectomy were performed using respectively 8, 10 and 12mmHg of CO2 pressure; In the OVH 8 Metoclopramide group, video-assisted OVH was performed by two portals with 8mmHg of pneumoperitoneum pressure and using metoclopramide in the anesthetic premedication.Todas as cadelas foram submetidas à esofagoscopia e pHmetria esofágica durante a cirurgia. It was not possible to attribute GER events to the decubitus changes inherent to the laparoscopic sterilization processes. Age and weight did not differ between bitches in all groups. Pneumoperitoneum time did not differ between OVE and OVH. None of the different pressures applied differently influenced the occurrence of GER. The higher the initial esophageal pH of the dogs, the lower the occurrence of GER. In all groups the esophageal pHs decreased throughout the surgical period, but the conventional groups remained with higher and more stable pHs. Regarding metoclopramide, two groups of dogs submitted to video-assisted two portals OVH with 8mmHg of CO2 pressure were compared, one of them received metoclopramide at the dose of 0.5mg.kg-1 i.m. at the time of premedication. In this study, there was a high occurrence of GER in both groups (57.1% in the non-metoclopramide group and 71.4% in the metoclopramide group) without any statistical difference between them. In conclusion, videosurgery achieved in a higher occurrence of GER compared to conventional surgeries, regardless of the pressure used and metoclopramide did not prevent or reduce the occurrence of GER in bitches submitted to video-assisted OVH, being the high occurrence attributed to the surgery technique. In this scenario, it is suggested continuous research for laparoscopic techniques that reduce (or avoid) GER, considering the importance of minimal invasion procedures.
publishDate 2019
dc.date.none.fl_str_mv 2019-12-18
2021-08-02T18:08:44Z
2021-08-02T18:08:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufsm.br/handle/1/21687
dc.identifier.dark.fl_str_mv ark:/26339/0013000013bcz
url http://repositorio.ufsm.br/handle/1/21687
identifier_str_mv ark:/26339/0013000013bcz
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
Centro de Ciências Rurais
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
Centro de Ciências Rurais
dc.source.none.fl_str_mv reponame:Manancial - Repositório Digital da UFSM
instname:Universidade Federal de Santa Maria (UFSM)
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instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Manancial - Repositório Digital da UFSM
collection Manancial - Repositório Digital da UFSM
repository.name.fl_str_mv Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv atendimento.sib@ufsm.br||tedebc@gmail.com
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