Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Manancial - Repositório Digital da UFSM |
dARK ID: | ark:/26339/001300000d722 |
Texto Completo: | http://repositorio.ufsm.br/handle/1/29091 |
Resumo: | In veterinary medicine, the literature on renal injury due to anesthesia is scarce due to the fact that follow-up in the immediate and even late postoperative period is often not performed, even if studies report that this is the time with the greatest risk of complications. Due to the scarcity of scientific material on this subject, renal injury becomes an important consequence, since even anesthetic procedures can favor this complication. The objective of this study was to evaluate dogs submitted to orchiectomy with different anesthetic protocols in order to diagnose immediate or delayed renal injury through diagnostic tests to evaluate renal function. Forty-five healthy male dogs, from five months to five years old, weighing 5 and 15 kilograms were selected and evaluated in the immediate (after 6 hours) and late (after three months) post-anesthetic period after elective orchiectomy. The animals were randomly allocated into three groups, which were control group (CG), dexmedetomidine group (DG) and acepromazine group (AG). For immediate evaluation, collections were performed at the end of the procedure (30 minutes), after 6 hours and 24 hours, with a return after 3 months for late evaluation collection. In the immediate renal evaluation there were no significant changes through the results of erythrogram, leukogram, biochemical examination and urinalysis, with only differences in the variable HR at stage 5 between the DG (dexmedetomidine) and CG (control) differing the median value between them. No significant changes were observed in the late evaluation, making evident the importance of the animal being healthy and monitored during the trans and postoperative period. It is concluded that there were no immediate and late changes regarding the effect of anesthesia in healthy dogs after undergoing elective orchiectomy using pre-anesthetic medication with vasodilator and vasoconstrictor drugs used. |
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Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletivaImmediate and delayed effects of anesthesia on renal function of dogs undergoing elective orchiectomyAnestesiaHipotensãoInjúria renalVasoconstriçãoVasodilataçãoAnesthesiaHypotensionKidney injuryVasoconstrictionVasodilationCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAIn veterinary medicine, the literature on renal injury due to anesthesia is scarce due to the fact that follow-up in the immediate and even late postoperative period is often not performed, even if studies report that this is the time with the greatest risk of complications. Due to the scarcity of scientific material on this subject, renal injury becomes an important consequence, since even anesthetic procedures can favor this complication. The objective of this study was to evaluate dogs submitted to orchiectomy with different anesthetic protocols in order to diagnose immediate or delayed renal injury through diagnostic tests to evaluate renal function. Forty-five healthy male dogs, from five months to five years old, weighing 5 and 15 kilograms were selected and evaluated in the immediate (after 6 hours) and late (after three months) post-anesthetic period after elective orchiectomy. The animals were randomly allocated into three groups, which were control group (CG), dexmedetomidine group (DG) and acepromazine group (AG). For immediate evaluation, collections were performed at the end of the procedure (30 minutes), after 6 hours and 24 hours, with a return after 3 months for late evaluation collection. In the immediate renal evaluation there were no significant changes through the results of erythrogram, leukogram, biochemical examination and urinalysis, with only differences in the variable HR at stage 5 between the DG (dexmedetomidine) and CG (control) differing the median value between them. No significant changes were observed in the late evaluation, making evident the importance of the animal being healthy and monitored during the trans and postoperative period. It is concluded that there were no immediate and late changes regarding the effect of anesthesia in healthy dogs after undergoing elective orchiectomy using pre-anesthetic medication with vasodilator and vasoconstrictor drugs used.Na medicina veterinária, a literatura sobre a lesão renal decorrente da anestesia é escassa, sendo que muitas vezes o acompanhamento no período pós-operatório imediato e até mesmo tardio não é realizado, mesmo que estudos relatem que este é o momento que apresenta maior risco de intercorrências. Pela escassez de material científico a cerca deste assunto, é que a injúria renal se torna uma consequência importante, pois até mesmo procedimentos anestésicos podem favorecer esta intercorrência. Objetivou-se avaliar cães submetidos a orquiectomia com diferentes protocolos anestésicos, a fim de diagnosticar injúria renal imediata ou tardia, através de exames diagnósticos de avaliação da função renal. Quarenta e cinco cães machos, saudáveis, de cinco meses a cinco anos, pesando 5 e 15 quilogramas foram selecionados e avaliados no no período pós-anestésico imediato (após 6 horas) e tardio (após três meses) após orquiectomia eletiva. Os animais foram alocados aleatoriamente em três grupos, sendo eles o grupo controle (GC), grupo dexmedetomidina (GD) e grupo acepromazina (GA). Para avaliação imediata foram realizadas coletas ao final do procedimento (30 minutos), após 6 horas e 24 horas, os quais retornaram 3 meses após para coleta de avaliação tardia. Na avaliação renal de forma imediata não houveram alterações significativas através dos resultados de eritrograma, leucograma, exame bioquímico e urinálise, havendo somente diferença na variável FC no momento 5 entre os GD (dexmedetomidina) e GC (controle) diferindo o valor da mediana entre os mesmos. De forma tardia não foram observadas alterações significativas, deixando evidente a importância do animal estar hígido e da monitorização durante o trans e pós-operatório. Conclui-se que não houveram alterações imediatas e tardias com relação ao efeito da anestesia em cães hígidos após passarem por orquiectomia eletiva utilizando medicação pré-anestésica com fármacos vasodilatadores e vasoconstritores utilizados.Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências RuraisSoares, André Vasconceloshttp://lattes.cnpq.br/1413221301096456Floriano, Beatriz PerezOliveira, Marília Teresa deSilva, Janine Giovanini da2023-05-16T10:52:57Z2023-05-16T10:52:57Z2023-03-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://repositorio.ufsm.br/handle/1/29091ark:/26339/001300000d722porAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2023-05-16T10:52:58Zoai:repositorio.ufsm.br:1/29091Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2023-05-16T10:52:58Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false |
dc.title.none.fl_str_mv |
Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva Immediate and delayed effects of anesthesia on renal function of dogs undergoing elective orchiectomy |
title |
Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva |
spellingShingle |
Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva Silva, Janine Giovanini da Anestesia Hipotensão Injúria renal Vasoconstrição Vasodilatação Anesthesia Hypotension Kidney injury Vasoconstriction Vasodilation CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva |
title_full |
Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva |
title_fullStr |
Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva |
title_full_unstemmed |
Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva |
title_sort |
Efeitos imediato e tardio da anestesia na função renal de cães submetidos a orquiectomia eletiva |
author |
Silva, Janine Giovanini da |
author_facet |
Silva, Janine Giovanini da |
author_role |
author |
dc.contributor.none.fl_str_mv |
Soares, André Vasconcelos http://lattes.cnpq.br/1413221301096456 Floriano, Beatriz Perez Oliveira, Marília Teresa de |
dc.contributor.author.fl_str_mv |
Silva, Janine Giovanini da |
dc.subject.por.fl_str_mv |
Anestesia Hipotensão Injúria renal Vasoconstrição Vasodilatação Anesthesia Hypotension Kidney injury Vasoconstriction Vasodilation CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
topic |
Anestesia Hipotensão Injúria renal Vasoconstrição Vasodilatação Anesthesia Hypotension Kidney injury Vasoconstriction Vasodilation CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
In veterinary medicine, the literature on renal injury due to anesthesia is scarce due to the fact that follow-up in the immediate and even late postoperative period is often not performed, even if studies report that this is the time with the greatest risk of complications. Due to the scarcity of scientific material on this subject, renal injury becomes an important consequence, since even anesthetic procedures can favor this complication. The objective of this study was to evaluate dogs submitted to orchiectomy with different anesthetic protocols in order to diagnose immediate or delayed renal injury through diagnostic tests to evaluate renal function. Forty-five healthy male dogs, from five months to five years old, weighing 5 and 15 kilograms were selected and evaluated in the immediate (after 6 hours) and late (after three months) post-anesthetic period after elective orchiectomy. The animals were randomly allocated into three groups, which were control group (CG), dexmedetomidine group (DG) and acepromazine group (AG). For immediate evaluation, collections were performed at the end of the procedure (30 minutes), after 6 hours and 24 hours, with a return after 3 months for late evaluation collection. In the immediate renal evaluation there were no significant changes through the results of erythrogram, leukogram, biochemical examination and urinalysis, with only differences in the variable HR at stage 5 between the DG (dexmedetomidine) and CG (control) differing the median value between them. No significant changes were observed in the late evaluation, making evident the importance of the animal being healthy and monitored during the trans and postoperative period. It is concluded that there were no immediate and late changes regarding the effect of anesthesia in healthy dogs after undergoing elective orchiectomy using pre-anesthetic medication with vasodilator and vasoconstrictor drugs used. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-05-16T10:52:57Z 2023-05-16T10:52:57Z 2023-03-29 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufsm.br/handle/1/29091 |
dc.identifier.dark.fl_str_mv |
ark:/26339/001300000d722 |
url |
http://repositorio.ufsm.br/handle/1/29091 |
identifier_str_mv |
ark:/26339/001300000d722 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria Brasil Medicina Veterinária UFSM Programa de Pós-Graduação em Medicina Veterinária Centro de Ciências Rurais |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria Brasil Medicina Veterinária UFSM Programa de Pós-Graduação em Medicina Veterinária Centro de Ciências Rurais |
dc.source.none.fl_str_mv |
reponame:Manancial - Repositório Digital da UFSM instname:Universidade Federal de Santa Maria (UFSM) instacron:UFSM |
instname_str |
Universidade Federal de Santa Maria (UFSM) |
instacron_str |
UFSM |
institution |
UFSM |
reponame_str |
Manancial - Repositório Digital da UFSM |
collection |
Manancial - Repositório Digital da UFSM |
repository.name.fl_str_mv |
Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM) |
repository.mail.fl_str_mv |
atendimento.sib@ufsm.br||tedebc@gmail.com |
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1815172326071730176 |