Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Manancial - Repositório Digital da UFSM |
Texto Completo: | http://repositorio.ufsm.br/handle/1/12819 |
Resumo: | Posttraumatic stress disorder (PTSD) is triggered after exposure to a traumatic event (experienced or witnessed) and its main symptomatology is composed of groups of avoidant, intrusive and hyperexcitability symptoms. It is estimated that 60.7% of men and 51.2% of women will experience at least one traumatic event during life and 8% of men and 20% of women will develop the disease. PTSD is associated with personal and economic costs, poor quality of life and about 1/3 of individuals will develop chronic symptoms despite adequate treatment. In January 2013, a fire of great proportions in a nightclub in Santa Maria-RS, known as KISS Nightclub, killed 242 young people and left hundreds with physical and psychological sequels. The great impact of this event caused an increase in the prevalence of several psychiatric disorders, among them PTSD. Given this, and the lack of effectiveness of standard treatment, other treatment strategies are necessary. Noninvasive neuromodulation techniques, such as Transcranial Direct Current Stimulation (tDCS), have been shown to be promising in the treatment of neuropsychiatric disorders. tDCS consists of the passage of small intensity electric current through the brain through electrodes, in order to modulate cortical excitability. It is an open experimental study with 8 patients whose primary objective was to evaluate the tDCS effect on PTSD symptoms, with exploratory analyzes to evaluate the effects on cognition and depressive and anxious symptoms. After treatment, there was improvement in PTSD symptoms, depression and anxiety, and these effects were maintained throughout the first month after treatment. The positive effects on cognition started slowly and progressively and were significant when assessed after 30 days of treatment. |
id |
UFSM_9e7877d10c7e7e45f5ef88d1087a1720 |
---|---|
oai_identifier_str |
oai:repositorio.ufsm.br:1/12819 |
network_acronym_str |
UFSM |
network_name_str |
Manancial - Repositório Digital da UFSM |
repository_id_str |
|
spelling |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumáticoEffects of transcranial direct-current stimulation in patients with post-traumatic stress disorderTranstorno do estresse pós-traumáticoNeuroestimulaçãoEstimulação transcraniana por corrente contínuaETCCPosttraumatic stress disorderPTSDNeuromodulationTranscranial direct current stimulationCNPQ::CIENCIAS DA SAUDEPosttraumatic stress disorder (PTSD) is triggered after exposure to a traumatic event (experienced or witnessed) and its main symptomatology is composed of groups of avoidant, intrusive and hyperexcitability symptoms. It is estimated that 60.7% of men and 51.2% of women will experience at least one traumatic event during life and 8% of men and 20% of women will develop the disease. PTSD is associated with personal and economic costs, poor quality of life and about 1/3 of individuals will develop chronic symptoms despite adequate treatment. In January 2013, a fire of great proportions in a nightclub in Santa Maria-RS, known as KISS Nightclub, killed 242 young people and left hundreds with physical and psychological sequels. The great impact of this event caused an increase in the prevalence of several psychiatric disorders, among them PTSD. Given this, and the lack of effectiveness of standard treatment, other treatment strategies are necessary. Noninvasive neuromodulation techniques, such as Transcranial Direct Current Stimulation (tDCS), have been shown to be promising in the treatment of neuropsychiatric disorders. tDCS consists of the passage of small intensity electric current through the brain through electrodes, in order to modulate cortical excitability. It is an open experimental study with 8 patients whose primary objective was to evaluate the tDCS effect on PTSD symptoms, with exploratory analyzes to evaluate the effects on cognition and depressive and anxious symptoms. After treatment, there was improvement in PTSD symptoms, depression and anxiety, and these effects were maintained throughout the first month after treatment. The positive effects on cognition started slowly and progressively and were significant when assessed after 30 days of treatment.O Transtorno do Estresse pós-Traumático (TEPT) é desencadeado após a exposição a um evento traumático (vivenciado ou testemunhado) e sua principal sintomatologia é composta por grupos de sintomas evitativos, intrusivos e de hiperexcitabilidade. Estima-se que 60,7% dos homens e 51,2% das mulheres experienciarão pelo menos um evento traumático durante a vida e que 8% dos homens e 20% das mulheres desenvolverão a doença. O TEPT está associado a custos pessoais e econômicos, qualidade de vida pobre e cerca de 1/3 dos indivíduos desenvolverão sintomas crônicos apesar do tratamento adequado. Em janeiro de 2013, um incêndio de grandes proporções em uma casa noturna em Santa Maria-RS, conhecida como Boate KISS, matou 242 jovens e deixou outras centenas com sequelas físicas e psicológicas. O grande impacto desse evento ocasionou aumento da prevalência de diversas patologias psiquiátricas, entre elas o TEPT. Diante disso, e da pouca efetividade do tratamento padrão, outras estratégias de tratamento se fazem necessárias. As técnicas de neuromodulação não invasiva, entre elas a Estimulação Transcraniana por Corrente Contínua (ETCC) têm se mostrado promissoras no tratamento de transtornos neuropsiquiátricos. A ETCC consiste na passagem de corrente elétrica de pequena intensidade pelo cérebro, através de eletrodos, com a finalidade de modular a excitabilidade cortical. Trata-se de um estudo experimental aberto com 8 pacientes cujo objetivo primário foi avaliar o efeito da ETCC nos sintomas de TEPT, com análises exploratórias para avaliar os efeitos em cognição e sintomas depressivos e ansiosos. Após o tratamento, houve melhora dos sintomas de TEPT, de depressão e de ansiedade, e esses efeitos se mantiveram durante todo o 1º mês após o tratamento. Os efeitos positivos na cognição iniciaram-se lenta e progressivamente e foram significativos quando avaliados após 30 dias do tratamento.Universidade Federal de Santa MariaBrasilCiências da SaúdeUFSMPrograma de Pós-Graduação em Ciências da SaúdeCentro de Ciências da SaúdeCunha, Angelo Batista Miralha dahttp://lattes.cnpq.br/1705812173977196Ribeiro, Tiango Aguiarhttp://lattes.cnpq.br/5738745231283624Pereira, Joanna Tatithhttp://lattes.cnpq.br/5641736415725738Barbosa, Mirian Hauboldhttp://lattes.cnpq.br/4000951779037880Marcolin, Kathy Aleixo dos Santos Ferreira2018-03-27T13:35:44Z2018-03-27T13:35:44Z2017-04-13info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://repositorio.ufsm.br/handle/1/12819porAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2018-03-27T13:35:44Zoai:repositorio.ufsm.br:1/12819Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2018-03-27T13:35:44Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false |
dc.title.none.fl_str_mv |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático Effects of transcranial direct-current stimulation in patients with post-traumatic stress disorder |
title |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático |
spellingShingle |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático Marcolin, Kathy Aleixo dos Santos Ferreira Transtorno do estresse pós-traumático Neuroestimulação Estimulação transcraniana por corrente contínua ETCC Posttraumatic stress disorder PTSD Neuromodulation Transcranial direct current stimulation CNPQ::CIENCIAS DA SAUDE |
title_short |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático |
title_full |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático |
title_fullStr |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático |
title_full_unstemmed |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático |
title_sort |
Efeito da estimulação transcraniana por corrente contínua em pacientes com transtorno do estresse pós-traumático |
author |
Marcolin, Kathy Aleixo dos Santos Ferreira |
author_facet |
Marcolin, Kathy Aleixo dos Santos Ferreira |
author_role |
author |
dc.contributor.none.fl_str_mv |
Cunha, Angelo Batista Miralha da http://lattes.cnpq.br/1705812173977196 Ribeiro, Tiango Aguiar http://lattes.cnpq.br/5738745231283624 Pereira, Joanna Tatith http://lattes.cnpq.br/5641736415725738 Barbosa, Mirian Haubold http://lattes.cnpq.br/4000951779037880 |
dc.contributor.author.fl_str_mv |
Marcolin, Kathy Aleixo dos Santos Ferreira |
dc.subject.por.fl_str_mv |
Transtorno do estresse pós-traumático Neuroestimulação Estimulação transcraniana por corrente contínua ETCC Posttraumatic stress disorder PTSD Neuromodulation Transcranial direct current stimulation CNPQ::CIENCIAS DA SAUDE |
topic |
Transtorno do estresse pós-traumático Neuroestimulação Estimulação transcraniana por corrente contínua ETCC Posttraumatic stress disorder PTSD Neuromodulation Transcranial direct current stimulation CNPQ::CIENCIAS DA SAUDE |
description |
Posttraumatic stress disorder (PTSD) is triggered after exposure to a traumatic event (experienced or witnessed) and its main symptomatology is composed of groups of avoidant, intrusive and hyperexcitability symptoms. It is estimated that 60.7% of men and 51.2% of women will experience at least one traumatic event during life and 8% of men and 20% of women will develop the disease. PTSD is associated with personal and economic costs, poor quality of life and about 1/3 of individuals will develop chronic symptoms despite adequate treatment. In January 2013, a fire of great proportions in a nightclub in Santa Maria-RS, known as KISS Nightclub, killed 242 young people and left hundreds with physical and psychological sequels. The great impact of this event caused an increase in the prevalence of several psychiatric disorders, among them PTSD. Given this, and the lack of effectiveness of standard treatment, other treatment strategies are necessary. Noninvasive neuromodulation techniques, such as Transcranial Direct Current Stimulation (tDCS), have been shown to be promising in the treatment of neuropsychiatric disorders. tDCS consists of the passage of small intensity electric current through the brain through electrodes, in order to modulate cortical excitability. It is an open experimental study with 8 patients whose primary objective was to evaluate the tDCS effect on PTSD symptoms, with exploratory analyzes to evaluate the effects on cognition and depressive and anxious symptoms. After treatment, there was improvement in PTSD symptoms, depression and anxiety, and these effects were maintained throughout the first month after treatment. The positive effects on cognition started slowly and progressively and were significant when assessed after 30 days of treatment. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-04-13 2018-03-27T13:35:44Z 2018-03-27T13:35:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufsm.br/handle/1/12819 |
url |
http://repositorio.ufsm.br/handle/1/12819 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria Brasil Ciências da Saúde UFSM Programa de Pós-Graduação em Ciências da Saúde Centro de Ciências da Saúde |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria Brasil Ciências da Saúde UFSM Programa de Pós-Graduação em Ciências da Saúde Centro de Ciências da Saúde |
dc.source.none.fl_str_mv |
reponame:Manancial - Repositório Digital da UFSM instname:Universidade Federal de Santa Maria (UFSM) instacron:UFSM |
instname_str |
Universidade Federal de Santa Maria (UFSM) |
instacron_str |
UFSM |
institution |
UFSM |
reponame_str |
Manancial - Repositório Digital da UFSM |
collection |
Manancial - Repositório Digital da UFSM |
repository.name.fl_str_mv |
Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM) |
repository.mail.fl_str_mv |
atendimento.sib@ufsm.br||tedebc@gmail.com |
_version_ |
1805922158444019712 |