Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS

Detalhes bibliográficos
Autor(a) principal: Marquezan, Patricia Kolling
Data de Publicação: 2021
Tipo de documento: Tese
Idioma: por
Título da fonte: Manancial - Repositório Digital da UFSM
Texto Completo: http://repositorio.ufsm.br/handle/1/22116
Resumo: This thesis is composed of three scientific articles whose objectives were to assess the prevalence, extent, risk indicators and intraoral distribution of underlying dentin shadows (UDS) (ICDAS 4 caries lesions) in a representative sample of 15-19-year-old adolescents from southern Brazil (Article I), to evaluate the association between UDS and oral health-related quality of life (OHRQoL) in the same sample of adolescents aged 15-19 years (Article II) and to study the progression of (UDS) in permanent posterior teeth over 1-2 years (Article III). Articles I and II derived from a population-based epidemiological study that evaluated a representative sample of the population of adolescents aged 15-19 years from Santa Maria, RS. Adolescents were clinically examined at the school environment for clinical characteristics and the OHRQoL was assessed using the OHIP-14 questionnaire. Article III was a prospective cohort stury that followed patients with UDS for a period of 1-2 years. Data analysis was performed in Articles I and II using multilevel Poisson regression models, whereas in Article III negative binomial regression models with generalized estimating equations were used due to the presence of clustered data. In Article I, the prevalence of UDS was low (8.8%), corresponding to 106 students. On average, this population had 0.13 lesions. The most affected teeth were the lower first molars followed by the upper first molars. The adjusted model showed that caries activity, age (≥17 years) and family income were significantly associated with the occurrence of UDS. In Article II, it was observed that UDS were negatively associated with OHRQoL in adolescents aged 15-19 years, being this effect dependent on the number of lesions. Adolescents who had 3-4 UDS lesions had a mean OHIP-14 score 35% higher than those without UDS, indicating poorer OHRQoL. Of the 7 domains, UDS were associated with the physical disability, psychological disability, social disability and handicap domains in the adolescent population under investigation (15-19 years). In relation to Article III, low progression rates were observed, being only 7% after 1 year (8/115) and 16.2% after 2 years (12/74). The risk analysis demonstrated that the subjects' skin color (non-white) and the presence of radiolucency at baseline were associated with lesion progression. The results presented in these articles show the low rates of prevalence/extent of UDS in the evaluated population and its association with caries activity and socio-demographic variables (Article I), its potential negative impact on HRQoL (Article II) and the low rates of progression of this type of lesion over 1-2 years, being associated with the individual's skin color and the presence of radiolucency on the baseline radiograph (Article III).
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spelling Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RSUnderlying dentin shadows (ICDAS 4) in adolescents and young adults in Santa Maria, RSCárie dentáriaDentição permanenteEstudo transversalEstudo de coortePrevalênciaProgressãoAvaliação de riscoQualidade de vidaDental cariesPermanent dentitionCross-sectional studyCohort studyPrevalenceDisease progressionRisk assessmentQuality of lifeCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIAThis thesis is composed of three scientific articles whose objectives were to assess the prevalence, extent, risk indicators and intraoral distribution of underlying dentin shadows (UDS) (ICDAS 4 caries lesions) in a representative sample of 15-19-year-old adolescents from southern Brazil (Article I), to evaluate the association between UDS and oral health-related quality of life (OHRQoL) in the same sample of adolescents aged 15-19 years (Article II) and to study the progression of (UDS) in permanent posterior teeth over 1-2 years (Article III). Articles I and II derived from a population-based epidemiological study that evaluated a representative sample of the population of adolescents aged 15-19 years from Santa Maria, RS. Adolescents were clinically examined at the school environment for clinical characteristics and the OHRQoL was assessed using the OHIP-14 questionnaire. Article III was a prospective cohort stury that followed patients with UDS for a period of 1-2 years. Data analysis was performed in Articles I and II using multilevel Poisson regression models, whereas in Article III negative binomial regression models with generalized estimating equations were used due to the presence of clustered data. In Article I, the prevalence of UDS was low (8.8%), corresponding to 106 students. On average, this population had 0.13 lesions. The most affected teeth were the lower first molars followed by the upper first molars. The adjusted model showed that caries activity, age (≥17 years) and family income were significantly associated with the occurrence of UDS. In Article II, it was observed that UDS were negatively associated with OHRQoL in adolescents aged 15-19 years, being this effect dependent on the number of lesions. Adolescents who had 3-4 UDS lesions had a mean OHIP-14 score 35% higher than those without UDS, indicating poorer OHRQoL. Of the 7 domains, UDS were associated with the physical disability, psychological disability, social disability and handicap domains in the adolescent population under investigation (15-19 years). In relation to Article III, low progression rates were observed, being only 7% after 1 year (8/115) and 16.2% after 2 years (12/74). The risk analysis demonstrated that the subjects' skin color (non-white) and the presence of radiolucency at baseline were associated with lesion progression. The results presented in these articles show the low rates of prevalence/extent of UDS in the evaluated population and its association with caries activity and socio-demographic variables (Article I), its potential negative impact on HRQoL (Article II) and the low rates of progression of this type of lesion over 1-2 years, being associated with the individual's skin color and the presence of radiolucency on the baseline radiograph (Article III).A presente tese é composta por três artigos científicos cujos objetivos foram avaliar a prevalência, extensão, os indicadores de risco e a distribuição intraoral das lesões de sombreamento em dentina (ICDAS 4) em uma amostra representativa de adolescentes de 15-19 anos do sul do Brasil (Artigo I), avaliar a associação entre lesões de sombreamento em dentina e qualidade de vida relacionada à saúde bucal (QVRSB) na mesma amostra de adolescentes de 15-19 anos (Artigo II) e estudar a progressão das lesões de sombreamento em dentina em dentes permanentes posteriores ao longo de 1-2 anos (Artigo III). Os artigos I e II derivam de um estudo epidemiológico de base populacional que avaliou uma amostra representativa da população de adolescentes de 15-19 de Santa Maria, RS. Os adolescentes foram examinados clinicamente em ambiente escolar em relação a características clínicas e a QVRSB foi avaliada através do questionário OHIP-14. O artigo III foi uma coorte prospectiva que acompanhou pacientes portadores de lesões de sombreamento por um período de 1-2 anos. A análise dos dados foi realizada nos Artigos I e II através de modelos multinível de regressão de Poisson enquanto no Artigo III foram utilizados modelos de regressão binomial negativa com equações de estimativas generalizas devido à presença de dados aglomerados. No artigo I, a prevalência de lesões de sombreamento foi baixa (8,8%), correspondendo a 106 escolares. Em média, esta população apresentou 0,13 lesões. Os dentes mais afetados foram os primeiros molares inferiores seguidos dos primeiros molares superiores. O modelo ajustado mostrou que atividade de cárie, idade (≥17 anos) e renda familiar foram significativamente associadas à ocorrência de sombreamentos em dentina. No Artigo II, observou-se que lesões de sombreamento em dentina foram negativamente associadas à QVRSB em adolescentes de 15-19 anos, sendo este efeito dependente no número de lesões. Adolescentes que possuíam 3-4 lesões de sombreamento apresentaram um escore médio do OHIP-14 35% maior do que aqueles sem lesões de sombreamento, indicando pior QVRSB. Dos 7 domínios, as lesões de sombreamento em dentina foram associadas com incapacidade física, incapacidade psicológica, incapacidade social e deficiência na população de adolescentes avaliada (15-19 anos). Em relação ao Artigo III, foram observadas baixas taxas de progressão, sendo somente 7% após 1 ano (8/115) e 16,2% após 2 anos (12/74). A análise de risco demonstrou que cor da pele (não branca) e imagem radiográfica na linha de base foram associados à progressão das lesões. Os resultados apresentados nestes artigos demonstram as baixas taxas de prevalência/extensão das lesões de sombreamento em dentina na população avaliada e sua associação com atividade de cárie e variáveis sócio-demográficas (Artigo I), seu potencial impacto negativo na QVRSB (Artigo II) e as baixas taxas de progressão desse tipo de lesão por 1-2 anos, estando associadas à cor da pele e presença de radiolucidez na radiografia inicial (Artigo III).Universidade Federal de Santa MariaBrasilOdontologiaUFSMPrograma de Pós-Graduação em Ciências OdontológicasCentro de Ciências da SaúdeZenkner, Júlio Eduardo do Amaralhttp://lattes.cnpq.br/8925619929042266Pinto, Alice SouzaDalla Nora , ÂngelaMoreira, Carlos Heitor CunhaCasagrande, LucianoMarquezan, Patricia Kolling2021-08-31T13:24:08Z2021-08-31T13:24:08Z2021-07-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdfhttp://repositorio.ufsm.br/handle/1/22116porAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2021-09-01T06:03:10Zoai:repositorio.ufsm.br:1/22116Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2021-09-01T06:03:10Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS
Underlying dentin shadows (ICDAS 4) in adolescents and young adults in Santa Maria, RS
title Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS
spellingShingle Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS
Marquezan, Patricia Kolling
Cárie dentária
Dentição permanente
Estudo transversal
Estudo de coorte
Prevalência
Progressão
Avaliação de risco
Qualidade de vida
Dental caries
Permanent dentition
Cross-sectional study
Cohort study
Prevalence
Disease progression
Risk assessment
Quality of life
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
title_short Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS
title_full Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS
title_fullStr Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS
title_full_unstemmed Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS
title_sort Lesões cariosas com sombreamento em dentina (ICDAS 4) em adolescentes e adultos jovens de Santa Maria, RS
author Marquezan, Patricia Kolling
author_facet Marquezan, Patricia Kolling
author_role author
dc.contributor.none.fl_str_mv Zenkner, Júlio Eduardo do Amaral
http://lattes.cnpq.br/8925619929042266
Pinto, Alice Souza
Dalla Nora , Ângela
Moreira, Carlos Heitor Cunha
Casagrande, Luciano
dc.contributor.author.fl_str_mv Marquezan, Patricia Kolling
dc.subject.por.fl_str_mv Cárie dentária
Dentição permanente
Estudo transversal
Estudo de coorte
Prevalência
Progressão
Avaliação de risco
Qualidade de vida
Dental caries
Permanent dentition
Cross-sectional study
Cohort study
Prevalence
Disease progression
Risk assessment
Quality of life
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
topic Cárie dentária
Dentição permanente
Estudo transversal
Estudo de coorte
Prevalência
Progressão
Avaliação de risco
Qualidade de vida
Dental caries
Permanent dentition
Cross-sectional study
Cohort study
Prevalence
Disease progression
Risk assessment
Quality of life
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
description This thesis is composed of three scientific articles whose objectives were to assess the prevalence, extent, risk indicators and intraoral distribution of underlying dentin shadows (UDS) (ICDAS 4 caries lesions) in a representative sample of 15-19-year-old adolescents from southern Brazil (Article I), to evaluate the association between UDS and oral health-related quality of life (OHRQoL) in the same sample of adolescents aged 15-19 years (Article II) and to study the progression of (UDS) in permanent posterior teeth over 1-2 years (Article III). Articles I and II derived from a population-based epidemiological study that evaluated a representative sample of the population of adolescents aged 15-19 years from Santa Maria, RS. Adolescents were clinically examined at the school environment for clinical characteristics and the OHRQoL was assessed using the OHIP-14 questionnaire. Article III was a prospective cohort stury that followed patients with UDS for a period of 1-2 years. Data analysis was performed in Articles I and II using multilevel Poisson regression models, whereas in Article III negative binomial regression models with generalized estimating equations were used due to the presence of clustered data. In Article I, the prevalence of UDS was low (8.8%), corresponding to 106 students. On average, this population had 0.13 lesions. The most affected teeth were the lower first molars followed by the upper first molars. The adjusted model showed that caries activity, age (≥17 years) and family income were significantly associated with the occurrence of UDS. In Article II, it was observed that UDS were negatively associated with OHRQoL in adolescents aged 15-19 years, being this effect dependent on the number of lesions. Adolescents who had 3-4 UDS lesions had a mean OHIP-14 score 35% higher than those without UDS, indicating poorer OHRQoL. Of the 7 domains, UDS were associated with the physical disability, psychological disability, social disability and handicap domains in the adolescent population under investigation (15-19 years). In relation to Article III, low progression rates were observed, being only 7% after 1 year (8/115) and 16.2% after 2 years (12/74). The risk analysis demonstrated that the subjects' skin color (non-white) and the presence of radiolucency at baseline were associated with lesion progression. The results presented in these articles show the low rates of prevalence/extent of UDS in the evaluated population and its association with caries activity and socio-demographic variables (Article I), its potential negative impact on HRQoL (Article II) and the low rates of progression of this type of lesion over 1-2 years, being associated with the individual's skin color and the presence of radiolucency on the baseline radiograph (Article III).
publishDate 2021
dc.date.none.fl_str_mv 2021-08-31T13:24:08Z
2021-08-31T13:24:08Z
2021-07-28
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufsm.br/handle/1/22116
url http://repositorio.ufsm.br/handle/1/22116
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Odontologia
UFSM
Programa de Pós-Graduação em Ciências Odontológicas
Centro de Ciências da Saúde
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Odontologia
UFSM
Programa de Pós-Graduação em Ciências Odontológicas
Centro de Ciências da Saúde
dc.source.none.fl_str_mv reponame:Manancial - Repositório Digital da UFSM
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Manancial - Repositório Digital da UFSM
collection Manancial - Repositório Digital da UFSM
repository.name.fl_str_mv Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv atendimento.sib@ufsm.br||tedebc@gmail.com
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