Hemoterapia em caninos: análise e indicações de 2.736 casos

Detalhes bibliográficos
Autor(a) principal: Dutra, Lara Seffrin
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Manancial - Repositório Digital da UFSM
Texto Completo: http://repositorio.ufsm.br/handle/1/16767
Resumo: Transfusion therapy aims the transfer of blood or blood products from donor to receptor according to the needs of the last. The use of blood products in veterinary medicine has been increasing in the last years, although more studies and spread of the knowledge regarding hemotherapy is needed. From fresh or stored whole blood (FWB, SWB), it is possible to obtain platelet-rich plasma (PRP), red blood cell concentrate (RBCC), platelet concentrate (PC), fresh, fresh frozen plasma or frozen plasma (P, FFP, FP) and cryoprecipitate (CRYO). The purpose of this study was to identify from the clinical and surgical routine of the Veterinary Teaching Hospital of the Federal University of Santa Maria (VTU-UFSM), canine patients whose clinical condition indicated the need of hemotherapy and to select the appropriate blood product. For that, 9,718 clinical records from the period of January 2015 to July 2018 and, based on clinical and laboratory parameters, 2,736 patients (32,53%) were identified as possible receptors. Of those, 1,692 (61,83%) were only anemic, 766 (28%) anemia and thrombocytopenia and 278, only thrombocytopenia. Indicated hemotherapy for each case were: 1,017 WB; 1,278 RBCC, 278 PRP or PC; 103 P, FP or FF, and in one case, CRYO. Associated clinical conditions related to the need of hemotherapy were: RBCC – secondary to cancer (28%), trauma (15%); WB – trauma (45%), viral infections (15%), hemoparasites (11%), PRC or PC – bone marrow depression associated to chemotherapy (26%), hemoparasites (23%), FP or FFP – viral infections (32%); CRYO – Von Willebrand disease, one case. The need of each blood product is variable depending to the studied regions and to the characteristics of the service. Reference centres for cancer should be prepared to offer a good blood bank service, as well as orthopaedic centres. Hemotherapy is a developing field in veterinary medicine and specific products are needed for particular clinical conditions, what reinforces the importance of a blood processing and storage service in order to offer the most indicated product for each patients need.
id UFSM_ceed7f9e17be77d721b6248dc9ed516d
oai_identifier_str oai:repositorio.ufsm.br:1/16767
network_acronym_str UFSM
network_name_str Manancial - Repositório Digital da UFSM
repository_id_str
spelling Hemoterapia em caninos: análise e indicações de 2.736 casosHemotherapy in canine: analysis and indications of 2.736 casesTransfusãoHemocomponentesCãesAnemiaTrombocitopeniaTransfusionBlood productsDogsThrombocytopeniaCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIATransfusion therapy aims the transfer of blood or blood products from donor to receptor according to the needs of the last. The use of blood products in veterinary medicine has been increasing in the last years, although more studies and spread of the knowledge regarding hemotherapy is needed. From fresh or stored whole blood (FWB, SWB), it is possible to obtain platelet-rich plasma (PRP), red blood cell concentrate (RBCC), platelet concentrate (PC), fresh, fresh frozen plasma or frozen plasma (P, FFP, FP) and cryoprecipitate (CRYO). The purpose of this study was to identify from the clinical and surgical routine of the Veterinary Teaching Hospital of the Federal University of Santa Maria (VTU-UFSM), canine patients whose clinical condition indicated the need of hemotherapy and to select the appropriate blood product. For that, 9,718 clinical records from the period of January 2015 to July 2018 and, based on clinical and laboratory parameters, 2,736 patients (32,53%) were identified as possible receptors. Of those, 1,692 (61,83%) were only anemic, 766 (28%) anemia and thrombocytopenia and 278, only thrombocytopenia. Indicated hemotherapy for each case were: 1,017 WB; 1,278 RBCC, 278 PRP or PC; 103 P, FP or FF, and in one case, CRYO. Associated clinical conditions related to the need of hemotherapy were: RBCC – secondary to cancer (28%), trauma (15%); WB – trauma (45%), viral infections (15%), hemoparasites (11%), PRC or PC – bone marrow depression associated to chemotherapy (26%), hemoparasites (23%), FP or FFP – viral infections (32%); CRYO – Von Willebrand disease, one case. The need of each blood product is variable depending to the studied regions and to the characteristics of the service. Reference centres for cancer should be prepared to offer a good blood bank service, as well as orthopaedic centres. Hemotherapy is a developing field in veterinary medicine and specific products are needed for particular clinical conditions, what reinforces the importance of a blood processing and storage service in order to offer the most indicated product for each patients need.A terapia transfusional visa a transferência de sangue ou hemoderivados do doador para o receptor de acordo com as necessidades deste último. O uso de hemoderivados em medicina veterinária tem aumentado nos últimos anos, embora sejam necessários mais estudos e divulgação do conhecimento sobre a hemoterapia. A partir de sangue total fresco ou armazenado (STF, ST), é possível obter plasma rico em plaquetas (PRP), concentrado de hemácias (CH), concentrado de plaquetas (CP), plasma fresco congelado fresco ou plasma congelado (PFC, PF, PC) e crioprecipitado (CRIO). O objetivo deste estudo foi identificar, a partir da rotina clínica e cirúrgica do Hospital de Clínicas Veterinárias da Universidade Federal de Santa Maria (HVU-UFSM), pacientes caninos cuja condição clínica indicou a necessidade de hemoterapia e selecionar o hemoderivado adequado. Para isso, foram revisados 9.718 prontuários clínicos no período de janeiro de 2015 a julho de 2018 e, com base nos parâmetros clínicos e laboratoriais, foram identificados 2.736 pacientes (32,53%) como possíveis receptores. Destes, 1.692 (61,83%) eram apenas anêmicos, 766 (28%) anêmicos e trombocitopenicos e 278, apenas trombocitopenicos. A hemoterapia indicada para cada caso foi: 1.017 ST; 1.278 CH, 278 PRP ou CP; 103 PFC, PF ou PC, e em um caso, CRIO. Condições clínicas associadas relacionadas à necessidade de hemoterapia foram: CH - secundário ao câncer (28%), trauma (15%); ST - trauma (45%), infecções virais (15%), hemoparasitas (11%), PRP ou CP - depressão da medula óssea associada à quimioterapia (26%), hemoparasitas (23%), PC ou PFC - infecções virais (32 %); CRIO - Doença de Von Willebrand, um caso. A necessidade de cada hemocomponente é variável, dependendo das regiões estudadas e das características do serviço. Os centros de referência para o câncer devem estar preparados para oferecer um bom serviço de banco de sangue, bem como centros ortopédicos. A hemoterapia é um campo em desenvolvimento na medicina veterinária e produtos específicos são necessários para determinadas condições clínicas, o que reforça a importância de um serviço de processamento e armazenamento de sangue, a fim de oferecer o produto mais indicado para cada necessidade do paciente.Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências RuraisKrause, Alexandrehttp://lattes.cnpq.br/7760558908777387Wolkmer, Patriciahttp://lattes.cnpq.br/5142205719893657Amaral, Anne Santos dohttp://lattes.cnpq.br/7867078112940824Dutra, Lara Seffrin2019-06-06T12:57:22Z2019-06-06T12:57:22Z2019-02-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://repositorio.ufsm.br/handle/1/16767porAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2019-06-07T06:01:46Zoai:repositorio.ufsm.br:1/16767Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2019-06-07T06:01:46Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Hemoterapia em caninos: análise e indicações de 2.736 casos
Hemotherapy in canine: analysis and indications of 2.736 cases
title Hemoterapia em caninos: análise e indicações de 2.736 casos
spellingShingle Hemoterapia em caninos: análise e indicações de 2.736 casos
Dutra, Lara Seffrin
Transfusão
Hemocomponentes
Cães
Anemia
Trombocitopenia
Transfusion
Blood products
Dogs
Thrombocytopenia
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Hemoterapia em caninos: análise e indicações de 2.736 casos
title_full Hemoterapia em caninos: análise e indicações de 2.736 casos
title_fullStr Hemoterapia em caninos: análise e indicações de 2.736 casos
title_full_unstemmed Hemoterapia em caninos: análise e indicações de 2.736 casos
title_sort Hemoterapia em caninos: análise e indicações de 2.736 casos
author Dutra, Lara Seffrin
author_facet Dutra, Lara Seffrin
author_role author
dc.contributor.none.fl_str_mv Krause, Alexandre
http://lattes.cnpq.br/7760558908777387
Wolkmer, Patricia
http://lattes.cnpq.br/5142205719893657
Amaral, Anne Santos do
http://lattes.cnpq.br/7867078112940824
dc.contributor.author.fl_str_mv Dutra, Lara Seffrin
dc.subject.por.fl_str_mv Transfusão
Hemocomponentes
Cães
Anemia
Trombocitopenia
Transfusion
Blood products
Dogs
Thrombocytopenia
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
topic Transfusão
Hemocomponentes
Cães
Anemia
Trombocitopenia
Transfusion
Blood products
Dogs
Thrombocytopenia
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description Transfusion therapy aims the transfer of blood or blood products from donor to receptor according to the needs of the last. The use of blood products in veterinary medicine has been increasing in the last years, although more studies and spread of the knowledge regarding hemotherapy is needed. From fresh or stored whole blood (FWB, SWB), it is possible to obtain platelet-rich plasma (PRP), red blood cell concentrate (RBCC), platelet concentrate (PC), fresh, fresh frozen plasma or frozen plasma (P, FFP, FP) and cryoprecipitate (CRYO). The purpose of this study was to identify from the clinical and surgical routine of the Veterinary Teaching Hospital of the Federal University of Santa Maria (VTU-UFSM), canine patients whose clinical condition indicated the need of hemotherapy and to select the appropriate blood product. For that, 9,718 clinical records from the period of January 2015 to July 2018 and, based on clinical and laboratory parameters, 2,736 patients (32,53%) were identified as possible receptors. Of those, 1,692 (61,83%) were only anemic, 766 (28%) anemia and thrombocytopenia and 278, only thrombocytopenia. Indicated hemotherapy for each case were: 1,017 WB; 1,278 RBCC, 278 PRP or PC; 103 P, FP or FF, and in one case, CRYO. Associated clinical conditions related to the need of hemotherapy were: RBCC – secondary to cancer (28%), trauma (15%); WB – trauma (45%), viral infections (15%), hemoparasites (11%), PRC or PC – bone marrow depression associated to chemotherapy (26%), hemoparasites (23%), FP or FFP – viral infections (32%); CRYO – Von Willebrand disease, one case. The need of each blood product is variable depending to the studied regions and to the characteristics of the service. Reference centres for cancer should be prepared to offer a good blood bank service, as well as orthopaedic centres. Hemotherapy is a developing field in veterinary medicine and specific products are needed for particular clinical conditions, what reinforces the importance of a blood processing and storage service in order to offer the most indicated product for each patients need.
publishDate 2019
dc.date.none.fl_str_mv 2019-06-06T12:57:22Z
2019-06-06T12:57:22Z
2019-02-28
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufsm.br/handle/1/16767
url http://repositorio.ufsm.br/handle/1/16767
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
Centro de Ciências Rurais
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
Centro de Ciências Rurais
dc.source.none.fl_str_mv reponame:Manancial - Repositório Digital da UFSM
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Manancial - Repositório Digital da UFSM
collection Manancial - Repositório Digital da UFSM
repository.name.fl_str_mv Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv atendimento.sib@ufsm.br||tedebc@gmail.com
_version_ 1805922142522441728