Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNIFESP |
| Texto Completo: | http://dx.doi.org/10.1128/JCM.00077-11 http://repositorio.unifesp.br/handle/11600/33576 |
Resumo: | The molecular prevalence of human parvovirus B19V (B19V) in bone marrow (BM) samples from 120 cases with cytopenias of unknown etiology was compared with that in samples from 45 BM donors (control group 1) and 120 oncohematological patients (control group 2) to determine the role that B19V genotypes may play in unexplained cytopenias. of the 285 participants, the BM samples of 39 (13.7%) contained B19V DNA (21 with genotype 1, 5 with genotype 2, and 13 with genotype 3). the prevalences of B19V were similar between case and control subjects (15.0% versus 12.7%, respectively). Genotypes 2 and 3 were associated with older age and were detected in similar proportions between case and control group 2 subjects. the results of this study do not support a role for B19V genotype variants in the etiology of unexplained cytopenias. |
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Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control StudyThe molecular prevalence of human parvovirus B19V (B19V) in bone marrow (BM) samples from 120 cases with cytopenias of unknown etiology was compared with that in samples from 45 BM donors (control group 1) and 120 oncohematological patients (control group 2) to determine the role that B19V genotypes may play in unexplained cytopenias. of the 285 participants, the BM samples of 39 (13.7%) contained B19V DNA (21 with genotype 1, 5 with genotype 2, and 13 with genotype 3). the prevalences of B19V were similar between case and control subjects (15.0% versus 12.7%, respectively). Genotypes 2 and 3 were associated with older age and were detected in similar proportions between case and control group 2 subjects. the results of this study do not support a role for B19V genotype variants in the etiology of unexplained cytopenias.Univ São Paulo, Fac Med, Dept Hematol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Translat Med, São Paulo, BrazilUniv São Paulo, Dept Infect Dis, São Paulo, BrazilHemoctr São Paulo, Fundacoes Prosangue, BR-05403000 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Translat Med, São Paulo, BrazilWeb of ScienceBlood Systems Research InstituteFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FAPESP: 06/55708-4CNPq: 136625/2008-8Amer Soc MicrobiologyUniversidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)Hemoctr São PauloGarcia, Sheila de OliveiraKleine Neto, Walter [UNIFESP]Costa, Antonio Charlys da [UNIFESP]Sanabani, Sabri Saeed [UNIFESP]Mendrone, AlfredoPereira, JulianaSabino, Ester Cerdeira2016-01-24T14:06:19Z2016-01-24T14:06:19Z2011-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1578-1580application/pdfhttp://dx.doi.org/10.1128/JCM.00077-11Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 49, n. 4, p. 1578-1580, 2011.10.1128/JCM.00077-11WOS000289080600058.pdf0095-1137http://repositorio.unifesp.br/handle/11600/33576WOS:000289080600058engJournal of Clinical Microbiologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-08T03:38:10Zoai:repositorio.unifesp.br/:11600/33576Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-08T03:38:10Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
| dc.title.none.fl_str_mv |
Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study |
| title |
Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study |
| spellingShingle |
Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study Garcia, Sheila de Oliveira |
| title_short |
Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study |
| title_full |
Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study |
| title_fullStr |
Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study |
| title_full_unstemmed |
Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study |
| title_sort |
Parvovirus among Patients with Cytopenia of Unknown Origin in Brazil: a Case-Control Study |
| author |
Garcia, Sheila de Oliveira |
| author_facet |
Garcia, Sheila de Oliveira Kleine Neto, Walter [UNIFESP] Costa, Antonio Charlys da [UNIFESP] Sanabani, Sabri Saeed [UNIFESP] Mendrone, Alfredo Pereira, Juliana Sabino, Ester Cerdeira |
| author_role |
author |
| author2 |
Kleine Neto, Walter [UNIFESP] Costa, Antonio Charlys da [UNIFESP] Sanabani, Sabri Saeed [UNIFESP] Mendrone, Alfredo Pereira, Juliana Sabino, Ester Cerdeira |
| author2_role |
author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Federal de São Paulo (UNIFESP) Hemoctr São Paulo |
| dc.contributor.author.fl_str_mv |
Garcia, Sheila de Oliveira Kleine Neto, Walter [UNIFESP] Costa, Antonio Charlys da [UNIFESP] Sanabani, Sabri Saeed [UNIFESP] Mendrone, Alfredo Pereira, Juliana Sabino, Ester Cerdeira |
| description |
The molecular prevalence of human parvovirus B19V (B19V) in bone marrow (BM) samples from 120 cases with cytopenias of unknown etiology was compared with that in samples from 45 BM donors (control group 1) and 120 oncohematological patients (control group 2) to determine the role that B19V genotypes may play in unexplained cytopenias. of the 285 participants, the BM samples of 39 (13.7%) contained B19V DNA (21 with genotype 1, 5 with genotype 2, and 13 with genotype 3). the prevalences of B19V were similar between case and control subjects (15.0% versus 12.7%, respectively). Genotypes 2 and 3 were associated with older age and were detected in similar proportions between case and control group 2 subjects. the results of this study do not support a role for B19V genotype variants in the etiology of unexplained cytopenias. |
| publishDate |
2011 |
| dc.date.none.fl_str_mv |
2011-04-01 2016-01-24T14:06:19Z 2016-01-24T14:06:19Z |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1128/JCM.00077-11 Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 49, n. 4, p. 1578-1580, 2011. 10.1128/JCM.00077-11 WOS000289080600058.pdf 0095-1137 http://repositorio.unifesp.br/handle/11600/33576 WOS:000289080600058 |
| url |
http://dx.doi.org/10.1128/JCM.00077-11 http://repositorio.unifesp.br/handle/11600/33576 |
| identifier_str_mv |
Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 49, n. 4, p. 1578-1580, 2011. 10.1128/JCM.00077-11 WOS000289080600058.pdf 0095-1137 WOS:000289080600058 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Journal of Clinical Microbiology |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
1578-1580 application/pdf |
| dc.publisher.none.fl_str_mv |
Amer Soc Microbiology |
| publisher.none.fl_str_mv |
Amer Soc Microbiology |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
| instname_str |
Universidade Federal de São Paulo (UNIFESP) |
| instacron_str |
UNIFESP |
| institution |
UNIFESP |
| reponame_str |
Repositório Institucional da UNIFESP |
| collection |
Repositório Institucional da UNIFESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
| repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
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1814268459407638528 |