Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
dARK ID: | ark:/48912/001300000sb9k |
Texto Completo: | http://dx.doi.org/10.1016/j.jcin.2017.08.039 https://repositorio.unifesp.br/handle/11600/54255 |
Resumo: | OBJECTIVES The aim of this study was to determine whether the association of small label size of the surgical valve with increased mortality after transcatheter valve-in-valve (ViV) implantation is, at least in part, related to pre-existing prosthesis-patient mismatch (PPM) (i.e., a bioprosthesis that is too small in relation to body size). BACKGROUND Transcatheter ViV implantation is an alternative for the treatment of patients with degenerated bioprostheses. Small label size of the surgical valve has been associated with increased mortality after ViV implantation. METHODS Data from 1,168 patients included in the VIVID (Valve-in-Valve International Data) registry were analyzed. Pre-existing PPM of the surgical valve was determined using a reference value of effective orifice area for each given model and size of implanted prosthetic valve indexed for body surface area. Severe PPM was defined according to the criteria proposed by the Valve Academic Research Consortium 2: indexed effective orifice area <0.65 cm(2)/m(2) if body mass index is < 30 kg/m(2) and < 0.6 cm(2)/m(2) if BMI is >= 30 kg/m(2). The primary study endpoint was 1-year mortality. RESULTS Among the 1,168 patients included in the registry, 89 (7.6%) had pre-existing severe PPM. Patients with severe PPM had higher 30-day (10.3%, p = 0.01) and 1-year (unadjusted: 28.6%, p < 0.001 adjusted: 19.3%, p = 0.03) mortality rates compared with patients with no severe PPM (4.3%, 11.9%, and 10.9%, respectively). After adjusting for surgical valve label size, Society of Thoracic Surgeons score, renal failure, diabetes, and stentless surgical valves, presence of pre-existing severe PPM was associated with increased risk for 1-year mortality (odds ratio: 1.88 95% confidence interval: 1.07 to 3.28 p = 0.03). Patients with severe PPM also more frequently harbored high post-procedural gradients (mean gradient >= 20 mm Hg). CONCLUSIONS Pre-existing PPM of the failed surgical valve is strongly and independently associated with increased risk for mortality following ViV implantation. (C) 2018 by the American College of Cardiology Foundation. |
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Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Proceduresprosthesis-patient-mismatchtranscatheter aortic valve replacementvalve-in-valveOBJECTIVES The aim of this study was to determine whether the association of small label size of the surgical valve with increased mortality after transcatheter valve-in-valve (ViV) implantation is, at least in part, related to pre-existing prosthesis-patient mismatch (PPM) (i.e., a bioprosthesis that is too small in relation to body size). BACKGROUND Transcatheter ViV implantation is an alternative for the treatment of patients with degenerated bioprostheses. Small label size of the surgical valve has been associated with increased mortality after ViV implantation. METHODS Data from 1,168 patients included in the VIVID (Valve-in-Valve International Data) registry were analyzed. Pre-existing PPM of the surgical valve was determined using a reference value of effective orifice area for each given model and size of implanted prosthetic valve indexed for body surface area. Severe PPM was defined according to the criteria proposed by the Valve Academic Research Consortium 2: indexed effective orifice area <0.65 cm(2)/m(2) if body mass index is < 30 kg/m(2) and < 0.6 cm(2)/m(2) if BMI is >= 30 kg/m(2). The primary study endpoint was 1-year mortality. RESULTS Among the 1,168 patients included in the registry, 89 (7.6%) had pre-existing severe PPM. Patients with severe PPM had higher 30-day (10.3%, p = 0.01) and 1-year (unadjusted: 28.6%, p < 0.001 adjusted: 19.3%, p = 0.03) mortality rates compared with patients with no severe PPM (4.3%, 11.9%, and 10.9%, respectively). After adjusting for surgical valve label size, Society of Thoracic Surgeons score, renal failure, diabetes, and stentless surgical valves, presence of pre-existing severe PPM was associated with increased risk for 1-year mortality (odds ratio: 1.88 95% confidence interval: 1.07 to 3.28 p = 0.03). Patients with severe PPM also more frequently harbored high post-procedural gradients (mean gradient >= 20 mm Hg). CONCLUSIONS Pre-existing PPM of the failed surgical valve is strongly and independently associated with increased risk for mortality following ViV implantation. (C) 2018 by the American College of Cardiology Foundation.Inst Univ Cardiol & Pneumol Quebec, 2725 Chemin St Foy, Quebec City, PQ G1V 4G5, CanadaEscola Paulista Med UNIFESP, Sao Paulo, BrazilFerraroto Hosp, Catania, ItalyUniv Leipzig, Leipzig, GermanyRabin Med Ctr, Petah Tiqwa, IsraelUniklin Koln Herzzentrum, Cologne, GermanyBelfast Hlth & Social Care Trust, Belfast, Antrim, North IrelandRoyal Brompton Harefield NHS Fdn Trust, London, EnglandUniv Washington, Seattle, WA 98195 USAHumanitas Hosp, Milan, ItalyUniv Senese, Azienda Osped, Siena, ItalyMed Centrum Leeuwarden, Leeuwarden, NetherlandsKerckhoff Klin, Bad Nauheim, GermanyUniv Padua, Padua, ItalyRobert Bosch Krankenhaus, Stuttgart, GermanyTel Aviv Sourasky Med Ctr, Tel Aviv, IsraelNatl Cerebral & Cardiovasc Ctr, Osaka, JapanSt Georges Univ London, London, EnglandFdn Toscana Gabriele Monasterio, Pisa, ItalyDeutsch Herzzentrum Berlin, Berlin, GermanyCtr Cardiol Nord, St Denis, FranceMount Carmel Columbus, Columbus, OH USASpedali Civili Brescia, Brescia, ItalyClin Pasteur, Toulouse, FranceHygeia Hosp, Athens, GreeceHospl Univ Virgen Victoria, Malaga, SpainOspede San Raffaele, Milan, ItalyEscola Paulista Med UNIFESP, Sao Paulo, BrazilWeb of ScienceCanadian Institutes of Health ResearchEdwards LifesciencesMedtronicAbbottCanadian Institutes of Health Research: FDN-143225Elsevier Science Inc2020-07-08T13:09:51Z2020-07-08T13:09:51Z2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion133-141http://dx.doi.org/10.1016/j.jcin.2017.08.039Jacc-Cardiovascular Interventions. New York, v. 11, n. 2, p. 133-141, 2018.10.1016/j.jcin.2017.08.0391936-8798https://repositorio.unifesp.br/handle/11600/54255WOS:000422763200008ark:/48912/001300000sb9kengJacc-Cardiovascular InterventionsNew Yorkinfo:eu-repo/semantics/openAccessPibarot, PhilippeSimonato, Matheus [UNIFESP]Barbanti, MarcoLinke, AxelKornowski, RanRudolph, TanjaSpence, MarkMoat, NeilAldea, GabrielMennuni, MarcoIadanza, AlessandroAmrane, HafidGaia, Diego [UNIFESP]Kim, Won-KeunNapodano, MassimoBaumbach, HardyFinkelstein, ArielKobayashi, JunjiroBrecker, StephenDon, CreightonCerillo, AlfredoUnbehaun, AxelAttias, DavidNejjari, MohammedJones, NoahFiorina, ClaudiaTchetche, DidierPhilippart, RaphaelSpargias, KonstantinosHernandez, Jose-MariaLatib, AzeemDvir, Dannyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2021-10-05T21:43:43Zoai:repositorio.unifesp.br/:11600/54255Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:34:58.363510Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures |
title |
Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures |
spellingShingle |
Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures Pibarot, Philippe prosthesis-patient-mismatch transcatheter aortic valve replacement valve-in-valve |
title_short |
Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures |
title_full |
Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures |
title_fullStr |
Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures |
title_full_unstemmed |
Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures |
title_sort |
Impact of Pre-Existing Prosthesis-Patient Mismatch on Survival Following Aortic Valve-in-Valve Procedures |
author |
Pibarot, Philippe |
author_facet |
Pibarot, Philippe Simonato, Matheus [UNIFESP] Barbanti, Marco Linke, Axel Kornowski, Ran Rudolph, Tanja Spence, Mark Moat, Neil Aldea, Gabriel Mennuni, Marco Iadanza, Alessandro Amrane, Hafid Gaia, Diego [UNIFESP] Kim, Won-Keun Napodano, Massimo Baumbach, Hardy Finkelstein, Ariel Kobayashi, Junjiro Brecker, Stephen Don, Creighton Cerillo, Alfredo Unbehaun, Axel Attias, David Nejjari, Mohammed Jones, Noah Fiorina, Claudia Tchetche, Didier Philippart, Raphael Spargias, Konstantinos Hernandez, Jose-Maria Latib, Azeem Dvir, Danny |
author_role |
author |
author2 |
Simonato, Matheus [UNIFESP] Barbanti, Marco Linke, Axel Kornowski, Ran Rudolph, Tanja Spence, Mark Moat, Neil Aldea, Gabriel Mennuni, Marco Iadanza, Alessandro Amrane, Hafid Gaia, Diego [UNIFESP] Kim, Won-Keun Napodano, Massimo Baumbach, Hardy Finkelstein, Ariel Kobayashi, Junjiro Brecker, Stephen Don, Creighton Cerillo, Alfredo Unbehaun, Axel Attias, David Nejjari, Mohammed Jones, Noah Fiorina, Claudia Tchetche, Didier Philippart, Raphael Spargias, Konstantinos Hernandez, Jose-Maria Latib, Azeem Dvir, Danny |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Pibarot, Philippe Simonato, Matheus [UNIFESP] Barbanti, Marco Linke, Axel Kornowski, Ran Rudolph, Tanja Spence, Mark Moat, Neil Aldea, Gabriel Mennuni, Marco Iadanza, Alessandro Amrane, Hafid Gaia, Diego [UNIFESP] Kim, Won-Keun Napodano, Massimo Baumbach, Hardy Finkelstein, Ariel Kobayashi, Junjiro Brecker, Stephen Don, Creighton Cerillo, Alfredo Unbehaun, Axel Attias, David Nejjari, Mohammed Jones, Noah Fiorina, Claudia Tchetche, Didier Philippart, Raphael Spargias, Konstantinos Hernandez, Jose-Maria Latib, Azeem Dvir, Danny |
dc.subject.por.fl_str_mv |
prosthesis-patient-mismatch transcatheter aortic valve replacement valve-in-valve |
topic |
prosthesis-patient-mismatch transcatheter aortic valve replacement valve-in-valve |
description |
OBJECTIVES The aim of this study was to determine whether the association of small label size of the surgical valve with increased mortality after transcatheter valve-in-valve (ViV) implantation is, at least in part, related to pre-existing prosthesis-patient mismatch (PPM) (i.e., a bioprosthesis that is too small in relation to body size). BACKGROUND Transcatheter ViV implantation is an alternative for the treatment of patients with degenerated bioprostheses. Small label size of the surgical valve has been associated with increased mortality after ViV implantation. METHODS Data from 1,168 patients included in the VIVID (Valve-in-Valve International Data) registry were analyzed. Pre-existing PPM of the surgical valve was determined using a reference value of effective orifice area for each given model and size of implanted prosthetic valve indexed for body surface area. Severe PPM was defined according to the criteria proposed by the Valve Academic Research Consortium 2: indexed effective orifice area <0.65 cm(2)/m(2) if body mass index is < 30 kg/m(2) and < 0.6 cm(2)/m(2) if BMI is >= 30 kg/m(2). The primary study endpoint was 1-year mortality. RESULTS Among the 1,168 patients included in the registry, 89 (7.6%) had pre-existing severe PPM. Patients with severe PPM had higher 30-day (10.3%, p = 0.01) and 1-year (unadjusted: 28.6%, p < 0.001 adjusted: 19.3%, p = 0.03) mortality rates compared with patients with no severe PPM (4.3%, 11.9%, and 10.9%, respectively). After adjusting for surgical valve label size, Society of Thoracic Surgeons score, renal failure, diabetes, and stentless surgical valves, presence of pre-existing severe PPM was associated with increased risk for 1-year mortality (odds ratio: 1.88 95% confidence interval: 1.07 to 3.28 p = 0.03). Patients with severe PPM also more frequently harbored high post-procedural gradients (mean gradient >= 20 mm Hg). CONCLUSIONS Pre-existing PPM of the failed surgical valve is strongly and independently associated with increased risk for mortality following ViV implantation. (C) 2018 by the American College of Cardiology Foundation. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018 2020-07-08T13:09:51Z 2020-07-08T13:09:51Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.jcin.2017.08.039 Jacc-Cardiovascular Interventions. New York, v. 11, n. 2, p. 133-141, 2018. 10.1016/j.jcin.2017.08.039 1936-8798 https://repositorio.unifesp.br/handle/11600/54255 WOS:000422763200008 |
dc.identifier.dark.fl_str_mv |
ark:/48912/001300000sb9k |
url |
http://dx.doi.org/10.1016/j.jcin.2017.08.039 https://repositorio.unifesp.br/handle/11600/54255 |
identifier_str_mv |
Jacc-Cardiovascular Interventions. New York, v. 11, n. 2, p. 133-141, 2018. 10.1016/j.jcin.2017.08.039 1936-8798 WOS:000422763200008 ark:/48912/001300000sb9k |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Jacc-Cardiovascular Interventions |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
133-141 |
dc.coverage.none.fl_str_mv |
New York |
dc.publisher.none.fl_str_mv |
Elsevier Science Inc |
publisher.none.fl_str_mv |
Elsevier Science Inc |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
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1818602511220604928 |