Fat and fiber consumption are associated with peripheral arterial disease in a cross-sectional study of a Japanese-Brazilian population

• Autor(a) principal: Gimeno, Suely Godoy Agostinho [UNIFESP]
• Data de Publicação: 2008
• Outros Autores: Hirai, Amelia Toyomi [UNIFESP], Harima, Helena Aiko [UNIFESP], Kikuchi, Mario Yasuo [UNIFESP], Simony, Rosana Farah [UNIFESP], Barros, Newton de [UNIFESP], Cardoso, Marly A., Ferreira, Sandra Roberta Gouvea, Japanese Brazilian Diab Study Grp
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• dARK ID: ark:/48912/001300001bzrj
• Texto Completo: http://dx.doi.org/10.1253/circj.72.44; http://repositorio.unifesp.br/handle/11600/30245
• topic: diet; fat consumption; fiber consumption; peripheral arterial disease; unsaturated fatty acid

Background the Western diet plays a role for the epidemics of obesity and related diseases. This study examined a possible association between peripheral arterial disease (PAD) and the dietary components of Japanese immigrants living in Brazil.Methods and Results in this cross-sectional study, 1,267 subjects (aged 30 years) with complete dietary, clinical and laboratory data were studied according to a standardized protocol. Ankle-to-brachial index was used to identify subjects with PAD. the overall prevalence of PAD was 14.6%. Subjects with PAD were older, had lower education and higher mean values of blood pressure, triglycerides, and fasting and 2-h plasma glucose levels compared with those without the disease. Among the subjects with PAD, the consumption of fiber from whole grains (3.0 vs 3.4g, p=0.001) and linoleic acids (11.0 vs 11.7g, p=0.017) were lower and intake of total (72.8 vs 69.1 a, p=0.016) and saturated fatty acids (17.4 vs 16.3g, p=0.012) were higher than those without PAD. Results of multiple logistic regression analysis showed a significant association between PAD with high total fat intake, low intake of fiber from fruit and oleic acid, independently of other variables.Conclusions Despite limitations in examining the cause-effect relationship, the data support the notion that diet could be important in reducing the occurrence of PAD.