Clinical efficacy of percutaneous renal revascularization with stent placement in atherosclerotic renovascular disease

• Autor(a) principal: Gonçalves, Janaina Andrea Altemar [UNIFESP]
• Data de Publicação: 2007
• Outros Autores: Amorim, Jorge Eduardo [UNIFESP], Soares Neto, Milton Macedo [UNIFESP], Ribeiro, Artur Beltrame [UNIFESP], Lima, Valter Correa [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0066-782X2007000100014; http://repositorio.unifesp.br/handle/11600/29347
• topic: renovascular hypertension; renal artery; angioplasty

Objective: To evaluate the clinical efficacy of percutaneous renal revascularization with stenting to control hypertension and preserve/restore renal function in patients with atherosclerotic renovascular disease.Methods: From May:11999 to Octoher/2003, 46 patients with atherosclerotic renal artery stenosis (ARAS) underwent revascularization with stenting. the indication for the procedure was hypertension control and/or renal function preservation/restoration. Clinical characteristics: age range: 33-84 years (median = 58.5 +/- 10.7), males: 26 (56.5%), 4 (10%) patients with dia betes mellitus, 21 (46%) patients with coronary artery disease, creatinine < 2.0mg/dl: 39 (60%), 6 patients (14%) with congestive heart failure, 20 (43%) patients with ostial stenosis and 15 (33%) patients with bilateral stenosis. Hypertension control was evaluated by the number of drugs used before the procedure and at follow-up (FU) and by blood pressure (BP) measurement.Results: the minimum follow-up was 7 months (range of 7-52, median: 23, mean: 24.2 +/- 15.2). There were no major complications. No patient experience any cardiovascular event. There was only one non-cadiac death (2%) and one technical failure in the treatment(2%). There was no serious complication in the procedure. None of the patients presented cardiovascular events. the renal function improved or stabilized in 32 patients (82%) and worsened in 4 (10%). the BP control improved in 19144 (43,8%) patients and worsened / stabilized in 6 patients (14%).Conclusion: Angioplasty with renal artery stenting for ARAS showed to be an effective treatment strategy to restore and preserve renal function and to control blood pressure.