Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos

Detalhes bibliográficos
Autor(a) principal: Amar, Ali [UNIFESP]
Data de Publicação: 2004
Outros Autores: Rapoport, Abrão [UNIFESP], Cervantes, Onivaldo [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0034-72992004000100007
http://repositorio.unifesp.br/handle/11600/1953
Resumo: AIM: To assess the results of treatment of bilateral neck metastases in patients with squamous cell carcinoma of upper aerodigestive tract. STUDY DESIGN: Retrospective case-series. MATERIAL AND METHODS: The charts of 855 patients with squamous cell carcinoma of mouth, oropharynx, hypopharynx and larynx who underwent ressection of primary tumor and radical neck dissection were reviewed. Ninety-six patients with histologically proven bilateral neck metastases were selected, 73 underwent bilateral radical neck dissection and 23 unilateral radical neck dissection and developed contralateral recurrence. The free disease survival and neck control rates were evaluated. RESULTS: Between 23 patients who underwent unilateral neck dissection and developed contralateral recurrence, only 18 were salvaged. The neck control after 2 years was achieved in 46% of patients. Between 73 patients who underwent bilateral neck dissection, 12 cases of neck recurrences were diagnosed and only 3 patients were salvaged. The neck control after 2 years was 77%, and the free disease survival was similar between the 2 groups, despite of the difference in neck control rates. CONCLUSION: The bilateral neck dissection in one stage was more effective to control neck disease but no difference of disease-free survival in comparison with two stage procedure was observed. Neck control was reached in most patients, but only 35% of those with bilateral metastases were free of disease after 2 years.
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spelling Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois temposBilateral metastases in squamous cell carcinoma of head and neck: surgical treatment in one or two stagesmetastaseslymph nodesquamous cell carcinomametástaseslinfonodocarcinoma de células escamosasAIM: To assess the results of treatment of bilateral neck metastases in patients with squamous cell carcinoma of upper aerodigestive tract. STUDY DESIGN: Retrospective case-series. MATERIAL AND METHODS: The charts of 855 patients with squamous cell carcinoma of mouth, oropharynx, hypopharynx and larynx who underwent ressection of primary tumor and radical neck dissection were reviewed. Ninety-six patients with histologically proven bilateral neck metastases were selected, 73 underwent bilateral radical neck dissection and 23 unilateral radical neck dissection and developed contralateral recurrence. The free disease survival and neck control rates were evaluated. RESULTS: Between 23 patients who underwent unilateral neck dissection and developed contralateral recurrence, only 18 were salvaged. The neck control after 2 years was achieved in 46% of patients. Between 73 patients who underwent bilateral neck dissection, 12 cases of neck recurrences were diagnosed and only 3 patients were salvaged. The neck control after 2 years was 77%, and the free disease survival was similar between the 2 groups, despite of the difference in neck control rates. CONCLUSION: The bilateral neck dissection in one stage was more effective to control neck disease but no difference of disease-free survival in comparison with two stage procedure was observed. Neck control was reached in most patients, but only 35% of those with bilateral metastases were free of disease after 2 years.OBJETIVO: Avaliar os resultados do tratamento dos pacientes com metástases cervicais bilaterais de carcinoma epidermóide das vias aerodigestivas superiores. FORMA DE ESTUDO: Série de casos retrospectiva. CASUÍSTICA E MÉTODO: Revisão dos prontuários de 855 pacientes com carcinoma epidermóide de boca, orofaringe, hipofaringe e laringe submetidos à ressecção do tumor primário e esvaziamento cervical radical entre 1977 e 1996. Foram selecionados 96 pacientes com metástases bilaterais confirmadas histologicamente, dos quais 73 foram submetidos inicialmente ao esvaziamento cervical bilateral (ECB) e 23 pacientes que se submeteram ao esvaziamento unilateral e, posteriormente, desenvolveram recidiva cervical contralateral. A evolução dos pacientes foi avaliada por meio da sobrevida livre de doença e do controle cervical. RESULTADOS: Entre os 23 pacientes submetidos ao esvaziamento unilateral (pN+) que desenvolveram recidiva contralateral, foram resgatados 18 pacientes. O controle da doença no pescoço em 2 anos foi alcançado em 46% dos pacientes. Entre os 73 pacientes submetidos ao esvaziamento bilateral (pN2c) ocorreram 12 casos de recidivas cervicais, dos quais apenas 3 foram resgatados. O controle da doença no pescoço em dois anos foi alcançado em 77% dos pacientes. A sobrevida livre de doença foi semelhante entre os 2 grupos, apesar da diferença observada na taxa de controle cervical. CONCLUSÃO: O esvaziamento bilateral em tempo único apresentou melhor controle da doença no pescoço, mas não alterou a sobrevida livre de doença neste grupo de pacientes. A despeito do controle da doença cervical ser obtido na maioria dos pacientes, apenas um terço daqueles com metástases bilaterais apresentaram doença controlada após 2 anos.Hospital Heliópolis Departamento de Cirurgia de Cabeça e Pescoço e OtorrinolaringologiaUNIFESP Serviço de Cirurgia de Cabeça e PescoçoUNIFESP, Serviço de Cirurgia de Cabeça e PescoçoSciELOABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-FacialHospital Heliópolis Departamento de Cirurgia de Cabeça e Pescoço e OtorrinolaringologiaUniversidade Federal de São Paulo (UNIFESP)Amar, Ali [UNIFESP]Rapoport, Abrão [UNIFESP]Cervantes, Onivaldo [UNIFESP]2015-06-14T13:30:15Z2015-06-14T13:30:15Z2004-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion42-45application/pdfhttp://dx.doi.org/10.1590/S0034-72992004000100007Revista Brasileira de Otorrinolaringologia. ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, v. 70, n. 1, p. 42-45, 2004.10.1590/S0034-72992004000100007S0034-72992004000100007.pdf0034-7299S0034-72992004000100007http://repositorio.unifesp.br/handle/11600/1953porRevista Brasileira de Otorrinolaringologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T13:41:17Zoai:repositorio.unifesp.br/:11600/1953Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T13:41:17Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos
Bilateral metastases in squamous cell carcinoma of head and neck: surgical treatment in one or two stages
title Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos
spellingShingle Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos
Amar, Ali [UNIFESP]
metastases
lymph node
squamous cell carcinoma
metástases
linfonodo
carcinoma de células escamosas
title_short Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos
title_full Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos
title_fullStr Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos
title_full_unstemmed Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos
title_sort Metástases cervicais bilaterais no carcinoma epidermóide de cabeça e pescoço: tratamento cirúrgico em um ou dois tempos
author Amar, Ali [UNIFESP]
author_facet Amar, Ali [UNIFESP]
Rapoport, Abrão [UNIFESP]
Cervantes, Onivaldo [UNIFESP]
author_role author
author2 Rapoport, Abrão [UNIFESP]
Cervantes, Onivaldo [UNIFESP]
author2_role author
author
dc.contributor.none.fl_str_mv Hospital Heliópolis Departamento de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Amar, Ali [UNIFESP]
Rapoport, Abrão [UNIFESP]
Cervantes, Onivaldo [UNIFESP]
dc.subject.por.fl_str_mv metastases
lymph node
squamous cell carcinoma
metástases
linfonodo
carcinoma de células escamosas
topic metastases
lymph node
squamous cell carcinoma
metástases
linfonodo
carcinoma de células escamosas
description AIM: To assess the results of treatment of bilateral neck metastases in patients with squamous cell carcinoma of upper aerodigestive tract. STUDY DESIGN: Retrospective case-series. MATERIAL AND METHODS: The charts of 855 patients with squamous cell carcinoma of mouth, oropharynx, hypopharynx and larynx who underwent ressection of primary tumor and radical neck dissection were reviewed. Ninety-six patients with histologically proven bilateral neck metastases were selected, 73 underwent bilateral radical neck dissection and 23 unilateral radical neck dissection and developed contralateral recurrence. The free disease survival and neck control rates were evaluated. RESULTS: Between 23 patients who underwent unilateral neck dissection and developed contralateral recurrence, only 18 were salvaged. The neck control after 2 years was achieved in 46% of patients. Between 73 patients who underwent bilateral neck dissection, 12 cases of neck recurrences were diagnosed and only 3 patients were salvaged. The neck control after 2 years was 77%, and the free disease survival was similar between the 2 groups, despite of the difference in neck control rates. CONCLUSION: The bilateral neck dissection in one stage was more effective to control neck disease but no difference of disease-free survival in comparison with two stage procedure was observed. Neck control was reached in most patients, but only 35% of those with bilateral metastases were free of disease after 2 years.
publishDate 2004
dc.date.none.fl_str_mv 2004-01-01
2015-06-14T13:30:15Z
2015-06-14T13:30:15Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0034-72992004000100007
Revista Brasileira de Otorrinolaringologia. ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, v. 70, n. 1, p. 42-45, 2004.
10.1590/S0034-72992004000100007
S0034-72992004000100007.pdf
0034-7299
S0034-72992004000100007
http://repositorio.unifesp.br/handle/11600/1953
url http://dx.doi.org/10.1590/S0034-72992004000100007
http://repositorio.unifesp.br/handle/11600/1953
identifier_str_mv Revista Brasileira de Otorrinolaringologia. ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, v. 70, n. 1, p. 42-45, 2004.
10.1590/S0034-72992004000100007
S0034-72992004000100007.pdf
0034-7299
S0034-72992004000100007
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista Brasileira de Otorrinolaringologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 42-45
application/pdf
dc.publisher.none.fl_str_mv ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
publisher.none.fl_str_mv ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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