Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C

Detalhes bibliográficos
Autor(a) principal: Carvalho-Filho, Roberto José de [UNIFESP]
Data de Publicação: 2012
Outros Autores: Narciso-Schiavon, Janaína Luz [UNIFESP], Lenz Tolentino, Luciano Henrique [UNIFESP], Schiavon, Leonardo de Lucca [UNIFESP], Ferraz, Maria Lucia G. [UNIFESP], Silva, Antonio Eduardo Benedito [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.3748/wjg.v18.i2.188
http://repositorio.unifesp.br/handle/11600/34528
Resumo: Sensory or motor peripheral neuropathy may be observed in a significant proportion of hepatitis C virus (HCV)-infected patients. However, central nervous system (CNS) involvement is uncommon, especially in cryoglobulin-negative subjects. We describe a case of peripheral neuropathy combined with an ischemic CNS event as primary manifestations of chronic HCV infection without cryoglobulinemia. Significant improvement was observed after antiviral therapy. We discuss the spectrum of neurological manifestations of HCV infection and review the literature. (C) 2012 Baishideng. All rights reserved.
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spelling Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis CHepatitis CCentral nervous systemPolyneuropathyInterferon-alphaSensory or motor peripheral neuropathy may be observed in a significant proportion of hepatitis C virus (HCV)-infected patients. However, central nervous system (CNS) involvement is uncommon, especially in cryoglobulin-negative subjects. We describe a case of peripheral neuropathy combined with an ischemic CNS event as primary manifestations of chronic HCV infection without cryoglobulinemia. Significant improvement was observed after antiviral therapy. We discuss the spectrum of neurological manifestations of HCV infection and review the literature. (C) 2012 Baishideng. All rights reserved.Universidade Federal de São Paulo, Hepatitis Sect, Div Gastroenterol, BR-04037003 São Paulo, BrazilUniversidade Federal de São Paulo, Hepatitis Sect, Div Gastroenterol, BR-04037003 São Paulo, BrazilWeb of ScienceBaishideng Publ Grp Co LtdUniversidade Federal de São Paulo (UNIFESP)Carvalho-Filho, Roberto José de [UNIFESP]Narciso-Schiavon, Janaína Luz [UNIFESP]Lenz Tolentino, Luciano Henrique [UNIFESP]Schiavon, Leonardo de Lucca [UNIFESP]Ferraz, Maria Lucia G. [UNIFESP]Silva, Antonio Eduardo Benedito [UNIFESP]2016-01-24T14:17:48Z2016-01-24T14:17:48Z2012-01-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion188-191http://dx.doi.org/10.3748/wjg.v18.i2.188World Journal of Gastroenterology. Beijing: Baishideng Publ Grp Co Ltd, v. 18, n. 2, p. 188-191, 2012.10.3748/wjg.v18.i2.1881007-9327http://repositorio.unifesp.br/handle/11600/34528WOS:000299345600012engWorld Journal of Gastroenterologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2016-02-19T10:40:32Zoai:repositorio.unifesp.br/:11600/34528Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652016-02-19T10:40:32Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C
title Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C
spellingShingle Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C
Carvalho-Filho, Roberto José de [UNIFESP]
Hepatitis C
Central nervous system
Polyneuropathy
Interferon-alpha
title_short Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C
title_full Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C
title_fullStr Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C
title_full_unstemmed Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C
title_sort Central nervous system vasculitis and polyneuropathy as first manifestations of hepatitis C
author Carvalho-Filho, Roberto José de [UNIFESP]
author_facet Carvalho-Filho, Roberto José de [UNIFESP]
Narciso-Schiavon, Janaína Luz [UNIFESP]
Lenz Tolentino, Luciano Henrique [UNIFESP]
Schiavon, Leonardo de Lucca [UNIFESP]
Ferraz, Maria Lucia G. [UNIFESP]
Silva, Antonio Eduardo Benedito [UNIFESP]
author_role author
author2 Narciso-Schiavon, Janaína Luz [UNIFESP]
Lenz Tolentino, Luciano Henrique [UNIFESP]
Schiavon, Leonardo de Lucca [UNIFESP]
Ferraz, Maria Lucia G. [UNIFESP]
Silva, Antonio Eduardo Benedito [UNIFESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Carvalho-Filho, Roberto José de [UNIFESP]
Narciso-Schiavon, Janaína Luz [UNIFESP]
Lenz Tolentino, Luciano Henrique [UNIFESP]
Schiavon, Leonardo de Lucca [UNIFESP]
Ferraz, Maria Lucia G. [UNIFESP]
Silva, Antonio Eduardo Benedito [UNIFESP]
dc.subject.por.fl_str_mv Hepatitis C
Central nervous system
Polyneuropathy
Interferon-alpha
topic Hepatitis C
Central nervous system
Polyneuropathy
Interferon-alpha
description Sensory or motor peripheral neuropathy may be observed in a significant proportion of hepatitis C virus (HCV)-infected patients. However, central nervous system (CNS) involvement is uncommon, especially in cryoglobulin-negative subjects. We describe a case of peripheral neuropathy combined with an ischemic CNS event as primary manifestations of chronic HCV infection without cryoglobulinemia. Significant improvement was observed after antiviral therapy. We discuss the spectrum of neurological manifestations of HCV infection and review the literature. (C) 2012 Baishideng. All rights reserved.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-14
2016-01-24T14:17:48Z
2016-01-24T14:17:48Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.3748/wjg.v18.i2.188
World Journal of Gastroenterology. Beijing: Baishideng Publ Grp Co Ltd, v. 18, n. 2, p. 188-191, 2012.
10.3748/wjg.v18.i2.188
1007-9327
http://repositorio.unifesp.br/handle/11600/34528
WOS:000299345600012
url http://dx.doi.org/10.3748/wjg.v18.i2.188
http://repositorio.unifesp.br/handle/11600/34528
identifier_str_mv World Journal of Gastroenterology. Beijing: Baishideng Publ Grp Co Ltd, v. 18, n. 2, p. 188-191, 2012.
10.3748/wjg.v18.i2.188
1007-9327
WOS:000299345600012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv World Journal of Gastroenterology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 188-191
dc.publisher.none.fl_str_mv Baishideng Publ Grp Co Ltd
publisher.none.fl_str_mv Baishideng Publ Grp Co Ltd
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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