Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor

Detalhes bibliográficos
Autor(a) principal: Mathez, Andreia Latanza Gomes [UNIFESP]
Data de Publicação: 2016
Outros Autores: Moroto, Debora [UNIFESP], Dib, Sergio Atala [UNIFESP], Sa, Joao Roberto de [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1186/s13098-016-0148-2
https://repositorio.unifesp.br/handle/11600/56033
Resumo: A rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trelat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism related to non-islet cell tumor hypoglycemia. Doege-Potter syndrome is the name given to paraneoplastic hypoinsulinemic hypoglycemia in presence of a solitary fibrous tumor. This report describes a case of a patient with hypoinsulinemic hypoglycemia and Leser-Trelat sign associated with a malignant solitary fibrous tumor with IGF2 secretion. Both conditions have improved after tumor excision.
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spelling Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumorInsulin-like growth factor 2HypoglycemiaTumorSeborrheic keratosisA rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trelat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism related to non-islet cell tumor hypoglycemia. Doege-Potter syndrome is the name given to paraneoplastic hypoinsulinemic hypoglycemia in presence of a solitary fibrous tumor. This report describes a case of a patient with hypoinsulinemic hypoglycemia and Leser-Trelat sign associated with a malignant solitary fibrous tumor with IGF2 secretion. Both conditions have improved after tumor excision.Univ Fed Sao Paulo, Div Endocrinol, Escola Paulista Med, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Div Endocrinol, Escola Paulista Med, Sao Paulo, SP, BrazilWeb of ScienceBiomed Central Ltd2020-07-22T13:23:06Z2020-07-22T13:23:06Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion-application/pdfhttp://dx.doi.org/10.1186/s13098-016-0148-2Diabetology & Metabolic Syndrome. London, v. 8, p. -, 2016.10.1186/s13098-016-0148-2WOS000375193500001.pdf1758-5996https://repositorio.unifesp.br/handle/11600/56033WOS:000375193500001engDiabetology & Metabolic SyndromeLondoninfo:eu-repo/semantics/openAccessMathez, Andreia Latanza Gomes [UNIFESP]Moroto, Debora [UNIFESP]Dib, Sergio Atala [UNIFESP]Sa, Joao Roberto de [UNIFESP]reponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-03T09:10:52Zoai:repositorio.unifesp.br/:11600/56033Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-03T09:10:52Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor
title Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor
spellingShingle Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor
Mathez, Andreia Latanza Gomes [UNIFESP]
Insulin-like growth factor 2
Hypoglycemia
Tumor
Seborrheic keratosis
title_short Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor
title_full Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor
title_fullStr Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor
title_full_unstemmed Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor
title_sort Seborrheic keratoses and severe hypoinsulinemic hypoglycemia associated with insulin grow factor 2 secretion by a malignant solitary fibrous tumor
author Mathez, Andreia Latanza Gomes [UNIFESP]
author_facet Mathez, Andreia Latanza Gomes [UNIFESP]
Moroto, Debora [UNIFESP]
Dib, Sergio Atala [UNIFESP]
Sa, Joao Roberto de [UNIFESP]
author_role author
author2 Moroto, Debora [UNIFESP]
Dib, Sergio Atala [UNIFESP]
Sa, Joao Roberto de [UNIFESP]
author2_role author
author
author
dc.contributor.author.fl_str_mv Mathez, Andreia Latanza Gomes [UNIFESP]
Moroto, Debora [UNIFESP]
Dib, Sergio Atala [UNIFESP]
Sa, Joao Roberto de [UNIFESP]
dc.subject.por.fl_str_mv Insulin-like growth factor 2
Hypoglycemia
Tumor
Seborrheic keratosis
topic Insulin-like growth factor 2
Hypoglycemia
Tumor
Seborrheic keratosis
description A rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trelat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism related to non-islet cell tumor hypoglycemia. Doege-Potter syndrome is the name given to paraneoplastic hypoinsulinemic hypoglycemia in presence of a solitary fibrous tumor. This report describes a case of a patient with hypoinsulinemic hypoglycemia and Leser-Trelat sign associated with a malignant solitary fibrous tumor with IGF2 secretion. Both conditions have improved after tumor excision.
publishDate 2016
dc.date.none.fl_str_mv 2016
2020-07-22T13:23:06Z
2020-07-22T13:23:06Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1186/s13098-016-0148-2
Diabetology & Metabolic Syndrome. London, v. 8, p. -, 2016.
10.1186/s13098-016-0148-2
WOS000375193500001.pdf
1758-5996
https://repositorio.unifesp.br/handle/11600/56033
WOS:000375193500001
url http://dx.doi.org/10.1186/s13098-016-0148-2
https://repositorio.unifesp.br/handle/11600/56033
identifier_str_mv Diabetology & Metabolic Syndrome. London, v. 8, p. -, 2016.
10.1186/s13098-016-0148-2
WOS000375193500001.pdf
1758-5996
WOS:000375193500001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Diabetology & Metabolic Syndrome
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv -
application/pdf
dc.coverage.none.fl_str_mv London
dc.publisher.none.fl_str_mv Biomed Central Ltd
publisher.none.fl_str_mv Biomed Central Ltd
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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